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Chemical Compound Review

AC1NSJT5     (2S)-6-amino-2-[[(2S)-1- [(2S)-2-[[(2S)-6...

Synonyms: 69671-17-6, NCGC00163208-01, alpha-Neoendorphin, Alpha Neo Endorphin
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Disease relevance of Alpha Neo Endorphin


High impact information on Alpha Neo Endorphin


Biological context of Alpha Neo Endorphin


Anatomical context of Alpha Neo Endorphin


Associations of Alpha Neo Endorphin with other chemical compounds


Gene context of Alpha Neo Endorphin


Analytical, diagnostic and therapeutic context of Alpha Neo Endorphin


  1. Expression in Escherichia coli of chemically synthesized gene for a novel opiate peptide alpha-neo-endorphin. Tanaka, S., Oshima, T., Ohsue, K., Ono, T., Oikawa, S., Takano, I., Noguchi, T., Kangawa, K., Minamino, N., Matsuo, H. Nucleic Acids Res. (1982) [Pubmed]
  2. Sequence and expression of the rat prodynorphin gene. Civelli, O., Douglass, J., Goldstein, A., Herbert, E. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  3. Immunohistochemical distribution of alpha-neo-endorphin/dynorphin neuronal systems in rat brain: evidence for colocalization. Weber, E., Roth, K.A., Barchas, J.D. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  4. Isolation and characterization of an endogenous C-terminal fragment of the alpha-neo-endorphin/dynorphin precursor from bovine caudate nucleus. Evans, C.J., Barchas, J.D., Esch, F.S., Böhlen, P., Weber, E. J. Neurosci. (1985) [Pubmed]
  5. The distribution of immunoreactive alpha-neo-endorphin in the central nervous system of the rat. Zamir, N., Palkovits, M., Brownstein, M.J. J. Neurosci. (1984) [Pubmed]
  6. Dynorphin-selective inhibition of adenylyl cyclase in guinea pig cerebellum membranes. Konkoy, C.S., Childers, S.R. Mol. Pharmacol. (1989) [Pubmed]
  7. Kappa opioid binding sites on the R1.1 murine lymphoma cell line: sensitivity to cations and guanine nucleotides. Lawrence, D.M., Bidlack, J.M. J. Neuroimmunol. (1992) [Pubmed]
  8. Enhancement of phagocytosis by dynorphin A in mouse peritoneal macrophages. Ichinose, M., Asai, M., Sawada, M. J. Neuroimmunol. (1995) [Pubmed]
  9. The complete amino acid sequence of alpha-neo-endorphin. Kangawa, K., Minamino, N., Chino, N., Sakakibara, S., Matsuo, H. Biochem. Biophys. Res. Commun. (1981) [Pubmed]
  10. Distribution of immunoreactive beta-neo-endorphin in discrete areas of the rat brain and pituitary gland: comparison with alpha-neo-endorphin. Zamir, N., Palkovits, M., Brownstein, M.J. J. Neurosci. (1984) [Pubmed]
  11. Evidence for a selective processing of proenkephalin B into different opioid peptide forms in particular regions of rat brain and pituitary. Seizinger, B.R., Grimm, C., Höllt, V., Herz, A. J. Neurochem. (1984) [Pubmed]
  12. Soluble metalloendopeptidase from rat brain: action on enkephalin-containing peptides and other bioactive peptides. Chu, T.G., Orlowski, M. Endocrinology (1985) [Pubmed]
  13. Ontogeny and regional distribution of proenkephalin- and prodynorphin-derived peptides and opioid receptors in rat hippocampus. Zamir, N., Quirion, R., Segal, M. Neuroscience (1985) [Pubmed]
  14. Mouse insulinoma beta TC3 cells express prodynorphin messenger ribonucleic acid and derived peptides: a unique cellular model for the study of prodynorphin biosynthesis and processing. Vieau, D., Seidah, N.G., Day, R. Endocrinology (1995) [Pubmed]
  15. Opioid-like immunoreactive neurons in secretomotor pathways of the guinea-pig ileum. Steele, P.A., Costa, M. Neuroscience (1990) [Pubmed]
  16. Characterization and localization of immunoreactive dynorphin, alpha-neo-endorphin, Met-enkephalin and substance P in human spinal cord. Przewłocki, R., Gramsch, C., Pasi, A., Herz, A. Brain Res. (1983) [Pubmed]
  17. Regulation of striatonigral prodynorphin peptides by dopaminergic agents. Trujillo, K.A., Day, R., Akil, H. Brain Res. (1990) [Pubmed]
  18. alpha-Neo-endorphin: receptor binding properties of the tritiated ligand. Houghten, R.A., Bartlett, S.M., Ostresh, J.M. Life Sci. (1983) [Pubmed]
  19. Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity. Day, R., Lazure, C., Basak, A., Boudreault, A., Limperis, P., Dong, W., Lindberg, I. J. Biol. Chem. (1998) [Pubmed]
  20. Characterization of proenkephalin B-derived opioid peptides in the human hypothalamo-neurohypophyseal axis. Arendt, R.M., Seizinger, B.R., Pasi, A., Mehraein, P., Herz, A. Brain Res. (1985) [Pubmed]
  21. Expression of chemically synthesized alpha-neo-endorphin gene fused to E. coli alkaline phosphatase. Ohsuye, K., Nomura, M., Tanaka, S., Kubota, I., Nakazato, H., Shinagawa, H., Nakata, A., Noguchi, T. Nucleic Acids Res. (1983) [Pubmed]
  22. Corelease of dynorphin-like immunoreactivity, luteinizing hormone, and follicle-stimulating hormone from rat adenohypophysis in vitro. Knepel, W., Schwaninger, M., Döhler, K.D. Endocrinology (1985) [Pubmed]
  23. Enterochromaffin (EC-) cells of the mammalian gastro-entero-pancreatic (GEP) endocrine system: cellular source of pro-dynorphin-derived peptides. Cetin, Y. Cell Tissue Res. (1988) [Pubmed]
  24. Immunohistochemical distribution of dynorphin B in rat brain: relation to dynorphin A and alpha-neo-endorphin systems. Weber, E., Barchas, J.D. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  25. Purification, sequence analysis, and cellular localization of a prodynorphin-derived peptide related to the alpha-neo-endorphin in the rhynchobdellid leech Theromyzon tessulatum. Salzet, M., Verger-Bocquet, M., Bulet, P., Beauvillain, J.C., Malecha, J. J. Biol. Chem. (1996) [Pubmed]
  26. Detection of prodynorphin end products in lizard, turtle, and alligator brain extracts. Goldsmith, A.M., Sei, C.A., Lance, V., Dores, R.M. Peptides (1992) [Pubmed]
  27. Alpha-neo-endorphin-like immunoreactivity in the cat brain stem. Marcos, P., Coveñas, R., Narváez, J.A., Tramu, G., Aguirre, J.A., González-Barón, S. Peptides (1993) [Pubmed]
  28. Precursors of molecules related to mammalian opioid peptides in brain of a marine worm. Dugimont, T., Guissi-Kadri, S., Curgy, J.J. Int. J. Pept. Protein Res. (1992) [Pubmed]
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