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Chemical Compound Review

Enkephalin     (2S)-2-[[(2S)-2-[2-[2-[[(2S)- 2-amino-3-(4...

Synonyms: Enkephalins, Enkephalin L, SureCN631959, AG-D-83124, HMDB01045, ...
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Disease relevance of leucine enkephalin


Psychiatry related information on leucine enkephalin


High impact information on leucine enkephalin


Chemical compound and disease context of leucine enkephalin


Biological context of leucine enkephalin


Anatomical context of leucine enkephalin


Associations of leucine enkephalin with other chemical compounds


Gene context of leucine enkephalin


Analytical, diagnostic and therapeutic context of leucine enkephalin


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  4. Serum leucine-enkephalin in bronchial carcinoma and its relation to tumour location. Gosney, J.R., Gosney, M.A., Lye, M. Thorax (1990) [Pubmed]
  5. Different subsets of displaced ganglion cells in the pigeon retina exhibit cholecystokinin-like and enkephalin-like immunoreactivities. Britto, L.R., Hamassaki-Britto, D.E. Neuroscience (1993) [Pubmed]
  6. DPen2-[DPen5]enkephalin, a delta opioid receptor-selective analog of [Leu]enkephalin, impairs avoidance learning in an automated shelf-jump task in rats. Weinberger, S.B., Gehrig, C.A., Martinez, J.L. Regul. Pept. (1989) [Pubmed]
  7. Short-term, intermediate-term, and long-term memories. Rosenzweig, M.R., Bennett, E.L., Colombo, P.J., Lee, D.W., Serrano, P.A. Behav. Brain Res. (1993) [Pubmed]
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  10. Effects of atropine on the changes of pain threshold and contents of leucine-enkephalin and catecholamines of the brain in rats induced by EA. Wang, Y., Wang, S., Wu, J. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine. (1992) [Pubmed]
  11. Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor. Kakidani, H., Furutani, Y., Takahashi, H., Noda, M., Morimoto, Y., Hirose, T., Asai, M., Inayama, S., Nakanishi, S., Numa, S. Nature (1982) [Pubmed]
  12. Impulse activity differentially regulates [Leu]enkephalin and catecholamine characters in the adrenal medulla. LaGamma, E.F., Adler, J.E., Black, I.B. Science (1984) [Pubmed]
  13. [Met]- and [Leu]enkephalin-like immunoreactive cell bodies and nerve fibres in the coeliac ganglion of the cat. Julé, Y., Clerc, N., Niel, J.P., Condamin, M. Neuroscience (1986) [Pubmed]
  14. Altered plasma leucine-enkephalin concentrations in patients with established hypertension may be involved in impaired regulation of blood pressure. Kraft, K., Kokorsch, F., Diehl, J., Kolloch, R., Stumpe, K.O. Journal of hypertension. Supplement : official journal of the International Society of Hypertension. (1989) [Pubmed]
  15. Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli. Matsas, R., Fulcher, I.S., Kenny, A.J., Turner, A.J. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
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  17. Kindling alters the calcium/calmodulin-dependent phosphorylation of synaptic plasma membrane proteins in rat hippocampus. Wasterlain, C.G., Farber, D.B. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  18. Partial characterization of the mRNA that codes for enkephalins in bovine adrenal medulla and human pheochromocytoma. Comb, M., Herbert, E., Crea, R. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  19. Reduced leucine-enkephalin--like immunoreactive substance in hamster basal ganglia after long-term ethanol exposure. Blum, K., Briggs, A.H., Elston, S.F., DeLallo, L., Sheridan, P.J., Sar, M. Science (1982) [Pubmed]
  20. Opioid receptors and endogenous opioids in diverse human and animal cancers. Zagon, I.S., McLaughlin, P.J., Goodman, S.R., Rhodes, R.E. J. Natl. Cancer Inst. (1987) [Pubmed]
  21. Neural control of the sphincter of Oddi. Physiologic role of enkephalins on the regulation of basal sphincter of Oddi motor activity in the cat. Behar, J., Biancani, P. Gastroenterology (1984) [Pubmed]
  22. Influence of opiates on alkali secretion by amphibian gastric and duodenal mucosa in vitro. Rees, W.D., Gibbons, L.C., Turnberg, L.A. Gastroenterology (1986) [Pubmed]
  23. Dynorphin-(1-13), an extraordinarily potent opioid peptide. Goldstein, A., Tachibana, S., Lowney, L.I., Hunkapiller, M., Hood, L. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  24. An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin. Lewis, R.V., Stern, A.S., Kimura, S., Rossier, J., Stein, S., Udenfriend, S. Science (1980) [Pubmed]
  25. Differential processing of prodynorphin and proenkephalin in specific regions of the rat brain. Zamir, N., Weber, E., Palkovits, M., Brownstein, M. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  26. Orientation and conformational preference of leucine-enkephalin at the surface of a hydrated dimyristoylphosphatidylcholine bilayer: NMR and MD simulation. Chandrasekhar, I., van Gunsteren, W.F., Zandomeneghi, G., Williamson, P.T., Meier, B.H. J. Am. Chem. Soc. (2006) [Pubmed]
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  29. Distribution, parabrachial region projection, and coexistence of neuropeptide and catecholamine cells of the nucleus of the solitary tract in the pigeon. Berk, M.L., Smith, S.E., Mullins, L.A. J. Comp. Neurol. (1993) [Pubmed]
  30. Neurotransmitters, receptors, and neuropeptides in the accessory optic system: an immunohistochemical survey in the pigeon (Columba livia). Britto, L.R., Hamassaki, D.E., Keyser, K.T., Karten, H.J. Vis. Neurosci. (1989) [Pubmed]
  31. Immunohistochemical localization of tyrosine hydroxylase, substance P, neuropeptide-Y and leucine-enkephalin in developing human retinal amacrine cells. Jotwani, G., Itoh, K., Wadhwa, S. Brain Res. Dev. Brain Res. (1994) [Pubmed]
  32. Localization of chemical messengers in magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei: an immunohistochemical study using experimental manipulations. Meister, B., Villar, M.J., Ceccatelli, S., Hökfelt, T. Neuroscience (1990) [Pubmed]
  33. Synthesis of enkephalins by adrenal medullary chromaffin cells: reserpine increases incorporation of radiolabeled amino acids. Wilson, S.P., Chang, K.J., Viveros, O.H. Proc. Natl. Acad. Sci. U.S.A. (1980) [Pubmed]
  34. Isolation, sequence analysis, and physiological properties of enkephalins in the nervous tissue of the shore crab Carcinus maenas L. Lüschen, W., Buck, F., Willig, A., Jaros, P.P. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  35. Expression and posttranslational processing of preprodynorphin complementary DNA in the mouse anterior pituitary cell line AtT-20. Devi, L., Gupta, P., Douglass, J. Mol. Endocrinol. (1989) [Pubmed]
  36. Enkephalins in human phaeochromocytomas: localization in immunoreactive, high molecular weight form to the soluble core of chromaffin granules. Parmer, R.J., O'Connor, D.T. J. Hypertens. (1988) [Pubmed]
  37. [Leu]enkephalin enhances active avoidance conditioning in rats and mice. Janak, P.H., Manly, J.J., Martinez, J.L. Neuropsychopharmacology (1994) [Pubmed]
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