Chemical Compound Review:
Flomoxef (6R,7R)-7-[2- (difluoromethylsulfanyl) ethan...
Synonyms:
Flomoxefo, Flomoxefum, FMOX, Flomoxef (INN), CHEMBL15413, ...
- In vitro activity of FK037, a new parenteral cephalosporin, against anaerobic bacteria. Kato, N., Kato, H., Tanaka, Y., Bando, K., Watanabe, K., Ueno, K. Antimicrob. Agents Chemother. (1993)
- Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli. Ishii, Y., Ohno, A., Taguchi, H., Imajo, S., Ishiguro, M., Matsuzawa, H. Antimicrob. Agents Chemother. (1995)
- TOC-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant Staphylococcus aureus. Hanaki, H., Akagi, H., Masaru, Y., Otani, T., Hyodo, A., Hiramatsu, K. Antimicrob. Agents Chemother. (1995)
- In vitro and in vivo activities of SCE-2787, a new parenteral cephalosporin with a broad antibacterial spectrum. Iwahi, T., Okonogi, K., Yamazaki, T., Shiki, S., Kondo, M., Miyake, A., Imada, A. Antimicrob. Agents Chemother. (1992)
- In-vitro activity of flomoxef, a new oxacephem group antibiotic, against Nocardia in comparison with other cephalosporins. Yazawa, K., Mikami, Y., Uno, J., Otozai, K., Arai, T. J. Antimicrob. Chemother. (1989)
- In vitro and in vivo antibacterial activities of OPC-20011, a novel parenteral broad-spectrum 2-oxaisocephem antibiotic. Matsumoto, M., Tamaoka, H., Ishikawa, H., Kikuchi, M. Antimicrob. Agents Chemother. (1998)
- beta-Lactamase produced by a highly beta-lactam-resistant strain of Bacteroides fragilis: an obstacle to the chemotherapy of experimental mixed infections. Ajiki, Y., Koga, T., Ohya, S., Takenouchi, T., Yasuda, H., Watanabe, K., Ueno, K. J. Antimicrob. Chemother. (1991)
- Relevance of antimicrobial agent-induced endotoxin release from in vitro cultured Escherichia coli and in vivo experimental infection with Gram-negative bacilli. Tsumura, H., Hiyama, E., Kodama, T., Sueda, T., Yokoyama, T. Int. J. Antimicrob. Agents (2003)
- In vitro activity of flomoxef in comparison to other cephalosporins. Simon, C., Simon, M., Plieth, C. Infection (1988)
- In vitro activity and stability against novel beta-lactamases of investigational beta-lactams (cefepime, cefpirome, flomoxef, SCE2787 and piperacillin plus tazobactam) in comparison with established compounds (cefotaxime, latamoxef and piperacillin). Bauernfeind, A., Schweighart, S., Eberlein, E., Jungwirth, R. Infection (1991)
- Pharmacokinetics and hemostasis following administration of a new, injectable oxacephem (6315-S, flomoxef) in volunteers and in patients with renal insufficiency. Andrassy, K., Koderisch, J., Gorges, K., Sonntag, H., Hirauchi, K. Infection (1991)
- In vitro antibacterial activities of FK037: a new parenteral cephalosporin. Inoue, K., Inoue, E., Mitsuhashi, S. Chemotherapy. (1995)
- Pharmacokinetics of flomoxef in mucosal tissue of the middle ear and mastoid following intravenous administration in humans. Saito, H., Kimura, T., Takeda, T., Kishimoto, S., Oguma, T., Shimamura, K. Chemotherapy. (1990)
- Effect of flomoxef on blood coagulation and alcohol metabolism. Uchida, K., Matsubara, T. Infection (1991)
- Effect of flomoxef on human platelet aggregation. Cazzola, M., Matera, M.G., Gusmitta, A., Rossi, F. Eur. J. Clin. Pharmacol. (1991)
- Perioperative antimicrobial prophylaxis in neurosurgery: clinical trial of systemic flomoxef administration and saline containing gentamicin for irrigation. Yamamoto, M., Jimbo, M., Ide, M., Tanaka, N., Umebara, Y., Hagiwara, S. Neurol. Med. Chir. (Tokyo) (1996)
- Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis. Hayashi, J., Kawarada, Y., Isaji, S., Yokoi, H., Higashiguchi, T. Pancreas (1996)
- Studies on the antibiotic transfer into the bile of canines with different bile duct pressures. Nakata, K., Kinoshita, H., Kubo, S., Igimi, H., Yamamoto, S. Chemotherapy. (1992)
- The meaning of the development of flomoxef and clinical experience in Japan. Ito, M., Ishigami, T. Infection (1991)
- Production of low-affinity penicillin-binding protein by low- and high-resistance groups of methicillin-resistant Staphylococcus aureus. Murakami, K., Nomura, K., Doi, M., Yoshida, T. Antimicrob. Agents Chemother. (1987)
- Effect of water mobility on drug hydrolysis rates in gelatin gels. Yoshioka, S., Aso, Y., Terao, T. Pharm. Res. (1992)
- In vitro and in vivo antibacterial activities of FK037, a new parenteral cephalosporin. Nishino, T., Otsuki, M., Hatano, K., Nishihara, Y. Chemotherapy. (1994)
- The in vitro activity of flomoxef compared to four other cephalosporins and imipenem. Shah, P.M., Knothe, H. Infection (1991)
- Excellent activity of FK037, a novel parenteral broad-spectrum cephalosporin, against methicillin-resistant staphylococci. Mine, Y., Watanabe, Y., Sakamoto, H., Hatano, K., Kuno, K., Kamimura, T., Tawara, S., Matsumoto, Y., Matsumoto, F., Kuwahara, S. J. Antibiot. (1993)
- Treatment of ESBL-producing Klebsiella pneumoniae bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates. Lee, C.H., Su, L.H., Tang, Y.F., Liu, J.W. J. Antimicrob. Chemother. (2006)
- Effects of added antibiotics on the basic properties of anti-washout-type fast-setting calcium phosphate cement. Takechi, M., Miyamoto, Y., Ishikawa, K., Nagayama, M., Kon, M., Asaoka, K., Suzuki, K. J. Biomed. Mater. Res. (1998)
- Diurnal variation in the biliary excretion of flomoxef in patients with percutaneous transhepatic biliary drainage. Hishikawa, S., Kobayashi, E., Sugimoto , K., Miyata, M., Fujimura, A. British journal of clinical pharmacology. (2001)
- Continuous monitoring of unbound flomoxef levels in rat blood using microdialysis and its new pharmacokinetic analysis. Saisho, Y., Umeda, T. Chem. Pharm. Bull. (1991)
- Dosing-time-dependent variation in biliary excretion of flomoxef in rats. Hishikawa, S., Sugimoto, K., Kobayashi, E., Kumagai, Y., Fujimura, A. Chronobiol. Int. (2003)