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Chemical Compound Review

Tocris-0573     2-(3H-imidazol-4-yl)-N- methyl-ethanamine

Synonyms: CHEMBL268490, SureCN119179, SureCN1908723, AC1Q4WOK, LS-78780, ...
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Disease relevance of N-methyl-histamine


High impact information on N-methyl-histamine


Chemical compound and disease context of N-methyl-histamine


Biological context of N-methyl-histamine


Anatomical context of N-methyl-histamine


Associations of N-methyl-histamine with other chemical compounds


Gene context of N-methyl-histamine


Analytical, diagnostic and therapeutic context of N-methyl-histamine


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  2. Is urine methylhistamine a useful marker for interstitial cystitis? Erickson, D.R., Kunselman, A.R., Bentley, C.M., Peters, K.M., Rovner, E.S., Demers, L.M., Tomaszewski, J.E. J. Urol. (2004) [Pubmed]
  3. Urinary excretion of N-methylhistamine as a marker of disease activity in inflammatory bowel disease. Winterkamp, S., Weidenhiller, M., Otte, P., Stolper, J., Schwab, D., Hahn, E.G., Raithel, M. Am. J. Gastroenterol. (2002) [Pubmed]
  4. Value of urinary N-methylhistamine measurements in childhood mastocytosis. Van Gysel, D., Oranje, A.P., Vermeiden, I., de Lijster de Raadt, J., Mulder, P.G., van Toorenenbergen, A.W. J. Am. Acad. Dermatol. (1996) [Pubmed]
  5. Long-term follow-up of indolent mastocytosis in adults. Kors, J.W., Van Doormaal, J.J., Breukelman, H., Van Voorst Vader, P.C., De Monchy, J.G. J. Intern. Med. (1996) [Pubmed]
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  13. Urinary N-methylhistamine as an indicator of bone marrow involvement in mastocytosis. Oranje, A.P., Mulder, P.G., Heide, R., Tank, B., Riezebos, P., van Toorenenbergen, A.W. Clin. Exp. Dermatol. (2002) [Pubmed]
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  19. Airway inflammation following exposure to diesel exhaust: a study of time kinetics using induced sputum. Nordenhäll, C., Pourazar, J., Blomberg, A., Levin, J.O., Sandström, T., Adelroth, E. Eur. Respir. J. (2000) [Pubmed]
  20. Increased levels of prostaglandin D(2) suggest macrophage activation in patients with primary pulmonary hypertension. Robbins, I.M., Barst, R.J., Rubin, L.J., Gaine, S.P., Price, P.V., Morrow, J.D., Christman, B.W. Chest (2001) [Pubmed]
  21. A highly potent and selective H3 agonist relaxes rabbit middle cerebral artery, in vitro. Ea-Kim, L., Oudart, N. Eur. J. Pharmacol. (1988) [Pubmed]
  22. Imatinib mesylate in the treatment of systemic mastocytosis: a phase II trial. Droogendijk, H.J., Kluin-Nelemans, H.J., van Doormaal, J.J., Oranje, A.P., van de Loosdrecht, A.A., van Daele, P.L. Cancer (2006) [Pubmed]
  23. Do the National Institute of Diabetes and Digestive and Kidney Diseases cystoscopic criteria associate with other clinical and objective features of interstitial cystitis? Erickson, D.R., Tomaszewski, J.E., Kunselman, A.R., Bentley, C.M., Peters, K.M., Rovner, E.S., Demers, L.M., Wheeler, M.A., Keay, S.K. J. Urol. (2005) [Pubmed]
  24. Urinary metabolites of histamine and leukotrienes before and after placebo-controlled challenge with ASA and food additives in chronic urticaria patients. Di Lorenzo, G., Pacor, M.L., Vignola, A.M., Profita, M., Esposito-Pellitteri, M., Biasi, D., Corrocher, R., Caruso, C. Allergy (2002) [Pubmed]
  25. Neutrophil adhesion to histamine stimulated cultured endothelial cells is primarily mediated via activation of phospholipase C and nitric oxide synthase isozymes. Schaefer, U., Schneider, A., Rixen, D., Neugebauer, E. Inflamm. Res. (1998) [Pubmed]
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  27. The intradermal effects of the H3 receptor agonist R alpha methylhistamine in human skin. Kavanagh, G.M., Sabroe, R.A., Greaves, M.W., Archer, C.B. Br. J. Dermatol. (1998) [Pubmed]
  28. The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in Parkinson's disease. Youdim, M.B., Riederer, P. Mov. Disord. (1993) [Pubmed]
  29. Involvement of histamine in suckling-induced release of oxytocin, prolactin and adrenocorticotropin in lactating rats. Schagen, F.H., Knigge, U., Kjaer, A., Larsen, P.J., Warberg, J. Neuroendocrinology (1996) [Pubmed]
  30. Quantification of inflammatory mediators in stool samples of patients with inflammatory bowel disorders and controls. Bischoff, S.C., Grabowsky, J., Manns, M.P. Dig. Dis. Sci. (1997) [Pubmed]
  31. No correlation between wine intolerance and histamine content of wine. Kanny, G., Gerbaux, V., Olszewski, A., Frémont, S., Empereur, F., Nabet, F., Cabanis, J.C., Moneret-Vautrin, D.A. J. Allergy Clin. Immunol. (2001) [Pubmed]
  32. Histamine measurement in whole blood and cell supernatants. A comparative study of two different radioimmunoassays. Rotz, B., Savaser, A., Werthmann, I., Lau, S., Wahn, U. Allergy (1991) [Pubmed]
  33. Activity of histamine metabolizing and catabolizing enzymes during reperfusion of isolated, globally ischemic rat hearts. Valen, G., Kaszaki, J., Szabo, I., Nagy, S., Vaage, J. Inflamm. Res. (1996) [Pubmed]
  34. Rapid and simple determination of histamine-N-methyl transferase activity by high-performance liquid chromatography with UV detection. Inoue, H., Hisamatsu, K.I., Yamauchi, M., Kumagai, N. Mediators of inflammation. (2001) [Pubmed]
  35. Urinary excretion of histamine, methylhistamine (1-MeHi) and methylimidazoleacetic acid (MeImAA) in mastocytosis: comparison of new HPLC methods with other present methods. Granerus, G., Wass, U. Agents Actions (1984) [Pubmed]
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