Gene Review:
CDC42EP2 - CDC42 effector protein (Rho GTPase binding) 2
Homo sapiens
Synonyms:
BORG1, Binder of Rho GTPases 1, CEP2, Cdc42 effector protein 2
Osada,
Kusuda,
Suzuki,
Sugano,
Hashimoto,
Schou,
Dalsgaard,
Clemmesen,
Dawson,
Yoshiga,
Nielsen,
Gustafsson,
Hildebrandt,
Secher,
Stratford,
Kennedy,
Pagura,
Gollish,
O'Donnell,
Lam,
Webb,
Barst,
McGoon,
McLaughlin,
Tapson,
Rich,
Rubin,
Wasserman,
Oudiz,
Shapiro,
Robbins,
Channick,
Badesch,
Rayburn,
Flinchbaugh,
Sigman,
Arneson,
Jeffs,
Gomberg-Maitland,
Tapson,
Benza,
McLaughlin,
Krichman,
Widlitz,
Barst,
Eckert,
Catcheside,
Smith,
Frith,
McEvoy,
O'Connor,
Cook,
Plaza,
Giner,
Picado,
Sureda,
Serrano,
Casan,
Pablo,
Sanchis,
Tapson,
Gomberg-Maitland,
McLaughlin,
Benza,
Widlitz,
Krichman,
Barst,
Salome,
Reddel,
Ware,
Roberts,
Jenkins,
Marks,
Woolcock,
O'Donnell,
Lam,
Webb,
Badesch,
Tapson,
McGoon,
Brundage,
Rubin,
Wigley,
Rich,
Barst,
Barrett,
Kral,
Jöbsis,
Loyd,
Murali,
Frost,
Girgis,
Bourge,
Ralph,
Elliott,
Hill,
Langleben,
Schilz,
McLaughlin,
Robbins,
Groves,
Shapiro,
Medsger,
Channick,
Simonneau,
Sitbon,
Robbins,
Frost,
Tapson,
Badesch,
Roux,
Rainisio,
Bodin,
Rubin,
O'Donnell,
D'Arsigny,
Webb,
- Chemosensitivity and perception of dyspnea in patients with a history of near-fatal asthma. Kikuchi, Y., Okabe, S., Tamura, G., Hida, W., Homma, M., Shirato, K., Takishima, T. N. Engl. J. Med. (1994)
- Impaired chemosensitivity and perception of dyspnoea in Parkinson's disease. Onodera, H., Okabe, S., Kikuchi, Y., Tsuda, T., Itoyama, Y. Lancet (2000)
- Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders. Hamilton, A.L., Killian, K.J., Summers, E., Jones, N.L. Am. J. Respir. Crit. Care Med. (1995)
- Diagnosis of Chlamydia trachomatis cervical infection by detection of amplified DNA with an enzyme immunoassay. Bobo, L., Coutlee, F., Yolken, R.H., Quinn, T., Viscidi, R.P. J. Clin. Microbiol. (1990)
- Long-term controlled trial of nocturnal nasal positive pressure ventilation in patients with severe COPD. Casanova, C., Celli, B.R., Tost, L., Soriano, E., Abreu, J., Velasco, V., Santolaria, F. Chest (2000)
- Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise. Blomstrand, E., Hassmén, P., Ek, S., Ekblom, B., Newsholme, E.A. Acta Physiol. Scand. (1997)
- Control of ventilation, breathlessness perception and alexithymia in near-fatal asthma. Plaza, V., Giner, J., Picado, C., Sureda, B., Serrano, J., Casan, P., Pablo, J.D., Sanchis, J. The Journal of asthma : official journal of the Association for the Care of Asthma. (2006)
- Ratings of perceived exertion and energy expenditure during light to moderate activity. Goss, F., Robertson, R., DaSilva, S., Suminski, R., Kang, J., Metz, K. Perceptual and motor skills. (2003)
- Sleep deprivation and cardiorespiratory function. Influence of intermittent submaximal exercise. Plyley, M.J., Shephard, R.J., Davis, G.M., Goode, R.C. European journal of applied physiology and occupational physiology. (1987)
- Borg proteins control septin organization and are negatively regulated by Cdc42. Joberty, G., Perlungher, R.R., Sheffield, P.J., Kinoshita, M., Noda, M., Haystead, T., Macara, I.G. Nat. Cell Biol. (2001)
- Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Channick, R.N., Simonneau, G., Sitbon, O., Robbins, I.M., Frost, A., Tapson, V.F., Badesch, D.B., Roux, S., Rainisio, M., Bodin, F., Rubin, L.J. Lancet (2001)
- Acute unloading of the work of breathing extends exercise duration in patients with heart failure. Mancini, D., Donchez, L., Levine, S. J. Am. Coll. Cardiol. (1997)
- Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension. Gomberg-Maitland, M., Tapson, V.F., Benza, R.L., McLaughlin, V.V., Krichman, A., Widlitz, A.C., Barst, R.J. Am. J. Respir. Crit. Care Med. (2005)
- Hypoxia suppresses symptom perception in asthma. Eckert, D.J., Catcheside, P.G., Smith, J.H., Frith, P.A., McEvoy, R.D. Am. J. Respir. Crit. Care Med. (2004)
- Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Badesch, D.B., Tapson, V.F., McGoon, M.D., Brundage, B.H., Rubin, L.J., Wigley, F.M., Rich, S., Barst, R.J., Barrett, P.S., Kral, K.M., Jöbsis, M.M., Loyd, J.E., Murali, S., Frost, A., Girgis, R., Bourge, R.C., Ralph, D.D., Elliott, C.G., Hill, N.S., Langleben, D., Schilz, R.J., McLaughlin, V.V., Robbins, I.M., Groves, B.M., Shapiro, S., Medsger, T.A. Ann. Intern. Med. (2000)
- Beraprost therapy for pulmonary arterial hypertension. Barst, R.J., McGoon, M., McLaughlin, V., Tapson, V., Rich, S., Rubin, L., Wasserman, K., Oudiz, R., Shapiro, S., Robbins, I.M., Channick, R., Badesch, D., Rayburn, B.K., Flinchbaugh, R., Sigman, J., Arneson, C., Jeffs, R. J. Am. Coll. Cardiol. (2003)
- Near-fatal asthma: clinical and physiologic features, perception of bronchoconstriction, and psychologic profile. Boulet, L.P., Deschesnes, F., Turcotte, H., Gignac, F. J. Allergy Clin. Immunol. (1991)
- Does inhaled albuterol improve diaphragmatic contractility in patients with chronic obstructive pulmonary disease? Hatipoğlu, U., Laghi, F., Tobin, M.J. Am. J. Respir. Crit. Care Med. (1999)
- Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. O'Donnell, D.E., Lam, M., Webb, K.A. Am. J. Respir. Crit. Care Med. (1999)
- Reference equations for the six-minute walk in healthy adults. Enright, P.L., Sherrill, D.L. Am. J. Respir. Crit. Care Med. (1998)
- Perception of induced bronchoconstriction in a community sample of adolescents. Wamboldt, M.Z., Bihun, J.T., Szefler, S., Hewitt, J. J. Allergy Clin. Immunol. (2000)
- Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease. O'Donnell, D.E., Lam, M., Webb, K.A. Am. J. Respir. Crit. Care Med. (1998)
- Effects of hyperoxia on ventilatory limitation during exercise in advanced chronic obstructive pulmonary disease. O'Donnell, D.E., D'Arsigny, C., Webb, K.A. Am. J. Respir. Crit. Care Med. (2001)
- Association of anxiety with perception of histamine induced bronchoconstriction in patients with asthma. Spinhoven, P., van Peski-Oosterbaan, A.S., Van der Does, A.J., Willems, L.N., Sterk, P.J. Thorax (1997)
- Effect of budesonide on the perception of induced airway narrowing in subjects with asthma. Salome, C.M., Reddel, H.K., Ware, S.I., Roberts, A.M., Jenkins, C.R., Marks, G.B., Woolcock, A.J. Am. J. Respir. Crit. Care Med. (2002)
- Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial. Tapson, V.F., Gomberg-Maitland, M., McLaughlin, V.V., Benza, R.L., Widlitz, A.C., Krichman, A., Barst, R.J. Chest (2006)
- Validation of the Hong Kong Chinese version of the St. George Respiratory Questionnaire in patients with bronchiectasis. Chan, S.L., Chan-Yeung, M.M., Ooi, G.C., Lam, C.L., Cheung, T.F., Lam, W.K., Tsang, K.W. Chest (2002)
- Moderate-intensity muscle pain can be produced and sustained during cycle ergometry. O'Connor, P.J., Cook, D.B. Medicine and science in sports and exercise. (2001)
- Kidneys extract BNP and NT-proBNP in healthy young men. Schou, M., Dalsgaard, M.K., Clemmesen, O., Dawson, E.A., Yoshiga, C.C., Nielsen, H.B., Gustafsson, F., Hildebrandt, P.R., Secher, N.H. J. Appl. Physiol. (2005)
- Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation. O'Donnell, D.E., Bain, D.J., Webb, K.A. Am. J. Respir. Crit. Care Med. (1997)
- Effects of regular salmeterol on lung function and exercise capacity in patients with chronic obstructive airways disease. Grove, A., Lipworth, B.J., Reid, P., Smith, R.P., Ramage, L., Ingram, C.G., Jenkins, R.J., Winter, J.H., Dhillon, D.P. Thorax (1996)
- Sequence analysis, gene expression, and chromosomal assignment of mouse Borg4 gene and its human orthologue. Osada, N., Kusuda, J., Suzuki, Y., Sugano, S., Hashimoto, K. J. Hum. Genet. (2000)
- The relationship between self-report and performance-related measures: questioning the content validity of timed tests. Stratford, P.W., Kennedy, D., Pagura, S.M., Gollish, J.D. Arthritis Rheum. (2003)
- Effects of dihydrocodeine on chemosensitivity and exercise tolerance in patients with chronic heart failure. Chua, T.P., Harrington, D., Ponikowski, P., Webb-Peploe, K., Poole-Wilson, P.A., Coats, A.J. J. Am. Coll. Cardiol. (1997)
- Evidence of reduced respiratory muscle endurance in patients with heart failure. Mancini, D.M., Henson, D., LaManca, J., Levine, S. J. Am. Coll. Cardiol. (1994)
- Language of dyspnea in assessment of patients with acute asthma treated with nebulized albuterol. Moy, M.L., Lantin, M.L., Harver, A., Schwartzstein, R.M. Am. J. Respir. Crit. Care Med. (1998)
- Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease. Belman, M.J., Botnick, W.C., Shin, J.W. Am. J. Respir. Crit. Care Med. (1996)