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Akr1c18  -  aldo-keto reductase family 1, member C18

Mus musculus

Synonyms: 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 20alpha-HSD, 20alpha-hydroxysteroid dehydrogenase, AW146047, ...
 
 
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Disease relevance of Akr1c18

 

High impact information on Akr1c18

 

Biological context of Akr1c18

 

Anatomical context of Akr1c18

 

Associations of Akr1c18 with chemical compounds

 

Other interactions of Akr1c18

 

Analytical, diagnostic and therapeutic context of Akr1c18

References

  1. Influence of genotype and the organ of origin on the subtype of T-cell in Moloney lymphomas induced by transfer of preleukemic cells from athymic and thymus-bearing mice. Asjö, B., Skoog, L., Palminger, I., Wiener, F., Isaak, D., Cerny, J., Fenyö, E.M. Cancer Res. (1985) [Pubmed]
  2. Establishment of continuous cultures of thy1.2+, Lyt1+, 2-T cells with purified interleukin 3. Hapel, A.J., Lee, J.C., Farrar, W.L., Ihle, J.N. Cell (1981) [Pubmed]
  3. In vivo T-lymphocyte response against spontaneous reticulum cell neoplasms in SJL/J mice. Weinstein, Y., Okon, E. J. Natl. Cancer Inst. (1980) [Pubmed]
  4. Prostaglandin F2alpha-induced expression of 20alpha-hydroxysteroid dehydrogenase involves the transcription factor NUR77. Stocco, C.O., Zhong, L., Sugimoto, Y., Ichikawa, A., Lau, L.F., Gibori, G. J. Biol. Chem. (2000) [Pubmed]
  5. Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase. Piekorz, R.P., Gingras, S., Hoffmeyer, A., Ihle, J.N., Weinstein, Y. Mol. Endocrinol. (2005) [Pubmed]
  6. Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene. Ishida, M., Hirabayashi, K., Suzuki, M., Yamanouchi, K., Nishihara, M. J. Reprod. Dev. (2003) [Pubmed]
  7. Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene. Hirabayashi, K., Ishida, M., Suzuki, M., Yamanouchi, K., Nishihara, M. Biochem. J. (2004) [Pubmed]
  8. Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization. Pelletier, G., Luu-The, V., Li, S., Labrie, F. Brain Res. Mol. Brain Res. (2004) [Pubmed]
  9. Expression of 20-alpha-hydroxysteroid dehydrogenase in mouse macrophages, hemopoietic cells, and cell lines and its induction by colony-stimulating factors. Hapel, A.J., Osborne, J.M., Fung, M.C., Young, I.G., Allan, W., Hume, D.A. J. Immunol. (1985) [Pubmed]
  10. 20 alpha hydroxysteroid dehydrogenase (20 alpha SDH) activity in New Zealand mice T lymphocytes and bone marrow cells: effect of age, sex, and castration. Fuks, A.S., Weinstein, Y. J. Immunol. (1979) [Pubmed]
  11. Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from athymic mice by a unique lymphokine. Ihle, J.N., Pepersack, L., Rebar, L. J. Immunol. (1981) [Pubmed]
  12. 20 alpha-hydroxysteroid dehydrogenase expression in hemopoietic cell cultures and its relationship to interleukin 3. Garland, J.M., Dexter, T.M. Eur. J. Immunol. (1982) [Pubmed]
  13. Characterization of a human 20alpha-hydroxysteroid dehydrogenase. Zhang, Y., Dufort, I., Rheault, P., Luu-The, V. J. Mol. Endocrinol. (2000) [Pubmed]
  14. Characteristics and inhibition by flavonoids of 20alpha-hydroxysteroid dehydrogenase activity in mouse tissues. Shimada, H., Miura, K., Imamura, Y. Life Sci. (2006) [Pubmed]
  15. Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone. Hershkovitz, L., Beuschlein, F., Klammer, S., Krup, M., Weinstein, Y. Endocrinology (2007) [Pubmed]
  16. Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family. Liu, H., Bellemare, V., Labrie, F., Luu-The, V. J. Steroid Biochem. Mol. Biol. (2007) [Pubmed]
  17. Immunosteroid as a regulator for Th1/Th2 balance: its possible role in autoimmune diseases. Matsuzaki, J., Tsuji, T., Imazeki, I., Ikeda, H., Nishimura, T. Autoimmunity (2005) [Pubmed]
  18. T cell recognition of Moloney leukemia virus proteins. III. T cell proliferative responses against gp70 are associated with the production of a lymphokine inducing 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes. Ihle, J.N., Lee, J.C., Rebar, L. J. Immunol. (1981) [Pubmed]
 
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