Gene Review:
Prg2 - proteoglycan 2, bone marrow
Mus musculus
Synonyms:
BMPG, Bone marrow proteoglycan, MBP, Mbp-1, Proteoglycan 2, ...
- Eosinophils alter colonic epithelial barrier function: role for major basic protein. Furuta, G.T., Nieuwenhuis, E.E., Karhausen, J., Gleich, G., Blumberg, R.S., Lee, J.J., Ackerman, S.J. Am. J. Physiol. Gastrointest. Liver Physiol. (2005)
- Comparative structure, proximal promoter elements, and chromosome location of the human eosinophil major basic protein genes. Plager, D.A., Weiler, D.A., Loegering, D.A., Johnson, W.B., Haley, L., Eddy, R.L., Shows, T.B., Gleich, G.J. Genomics (2001)
- Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis. Sundvall, M., Jirholt, J., Yang, H.T., Jansson, L., Engström, A., Pettersson, U., Holmdahl, R. Nat. Genet. (1995)
- Increased levels of myelin basic protein transcripts in virus-induced demyelination. Kristensson, K., Holmes, K.V., Duchala, C.S., Zeller, N.K., Lazzarini, R.A., Dubois-Dalcq, M. Nature (1986)
- Interstrain cross-reactive idiotypes on monoclonal antibodies to an encephalitogenic myelin basic protein peptide. Zhou, S.R., Whitaker, J.N. Clin. Immunol. Immunopathol. (1992)
- Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Goverman, J., Woods, A., Larson, L., Weiner, L.P., Hood, L., Zaller, D.M. Cell (1993)
- Autoimmune T cells: immune recognition of normal and variant peptide epitopes and peptide-based therapy. Urban, J.L., Horvath, S.J., Hood, L. Cell (1989)
- Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Lehmann, P.V., Forsthuber, T., Miller, A., Sercarz, E.E. Nature (1992)
- A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis. Gautam, A.M., Pearson, C.I., Smilek, D.E., Steinman, L., McDevitt, H.O. J. Exp. Med. (1992)
- The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity. Kean, R.B., Spitsin, S.V., Mikheeva, T., Scott, G.S., Hooper, D.C. J. Immunol. (2000)
- Desferrioxamine suppresses experimental allergic encephalomyelitis induced by MBP in SJL mice. Pedchenko, T.V., LeVine, S.M. J. Neuroimmunol. (1998)
- The murine eosinophil major basic protein gene (Prg2) maps to chromosome 2. Denzler, K.L., Levin, W.J., Quiram, P.A., Lee, N.A., Lee, J.J. Mamm. Genome (1997)
- The identification and cloning of a murine major basic protein gene expressed in eosinophils. Larson, K.A., Horton, M.A., Madden, B.J., Gleich, G.J., Lee, N.A., Lee, J.J. J. Immunol. (1995)
- Eosinophil major basic protein-1 does not contribute to allergen-induced airway pathologies in mouse models of asthma. Denzler, K.L., Farmer, S.C., Crosby, J.R., Borchers, M., Cieslewicz, G., Larson, K.A., Cormier-Regard, S., Lee, N.A., Lee, J.J. J. Immunol. (2000)
- Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation. Krakowski, M.L., Owens, T. Eur. J. Immunol. (2000)
- The thymus plays a role in oral tolerance in experimental autoimmune encephalomyelitis. Song, F., Guan, Z., Gienapp, I.E., Shawler, T., Benson, J., Whitacre, C.C. J. Immunol. (2006)
- Lack of eosinophil peroxidase or major basic protein impairs defense against murine filarial infection. Specht, S., Saeftel, M., Arndt, M., Endl, E., Dubben, B., Lee, N.A., Lee, J.J., Hoerauf, A. Infect. Immun. (2006)
- Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice. Mokhtarian, F., McFarlin, D.E., Raine, C.S. Nature (1984)
- Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Chen, Y., Kuchroo, V.K., Inobe, J., Hafler, D.A., Weiner, H.L. Science (1994)
- Interleukin-5 expression in the bone marrow of sensitized Balb/c mice after allergen challenge. Minshall, E.M., Schleimer, R., Cameron, L., Minnicozzi, M., Egan, R.W., Gutierrez-Ramos, J.C., Eidelman, D.H., Hamid, Q. Am. J. Respir. Crit. Care Med. (1998)
- Induction, distribution and modulation of upper airway allergic inflammation in mice. Hussain, I., Randolph, D., Brody, S.L., Song, S.K., Hsu, A., Kahn, A.M., Chaplin, D.D., Hamilos, D.L. Clin. Exp. Allergy (2001)
- Influence of a dominant cryptic epitope on autoimmune T cell tolerance. Anderton, S.M., Viner, N.J., Matharu, P., Lowrey, P.A., Wraith, D.C. Nat. Immunol. (2002)
- Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis. Zamvil, S.S., Mitchell, D.J., Lee, N.E., Moore, A.C., Waldor, M.K., Sakai, K., Rothbard, J.B., McDevitt, H.O., Steinman, L., Acha-Orbea, H. J. Exp. Med. (1988)
- Identification of a new murine eosinophil major basic protein (mMBP) gene: cloning and characterization of mMBP-2. Macias, M.P., Welch, K.C., Denzler, K.L., Larson, K.A., Lee, N.A., Lee, J.J. J. Leukoc. Biol. (2000)
- Development and functional analysis of eosinophils from murine embryonic stem cells. Hamaguchi-Tsuru, E., Nobumoto, A., Hirose, N., Kataoka, S., Fujikawa-Adachi, K., Furuya, M., Tominaga, A. Br. J. Haematol. (2004)
- Eosinophil major basic protein: first identified natural heparanase-inhibiting protein. Temkin, V., Aingorn, H., Puxeddu, I., Goldshmidt, O., Zcharia, E., Gleich, G.J., Vlodavsky, I., Levi-Schaffer, F. J. Allergy Clin. Immunol. (2004)