Gene Review:
FUT3 - fucosyltransferase 3 (galactoside 3(4)-L...
Homo sapiens
Synonyms:
Blood group Lewis alpha-4-fucosyltransferase, CD174, FT3B, FucT-III, Fucosyltransferase 3, ...
- Expression of human alpha(1,3)fucosyltransferase antisense sequences inhibits selectin-mediated adhesion and liver metastasis of colon carcinoma cells. Weston, B.W., Hiller, K.M., Mayben, J.P., Manousos, G.A., Bendt, K.M., Liu, R., Cusack, J.C. Cancer Res. (1999)
- Peritoneal colonization by human pancreatic cancer cells is inhibited by antisense FUT3 sequence. Aubert, M., Panicot-Dubois, L., Crotte, C., Sbarra, V., Lombardo, D., Sadoulet, M.O., Mas, E. Int. J. Cancer (2000)
- Influence of the combined ABO, FUT2, and FUT3 polymorphism on susceptibility to Norwalk virus attachment. Marionneau, S., Airaud, F., Bovin, N.V., Le Pendu, J., Ruvoën-Clouet, N. J. Infect. Dis. (2005)
- Expression of Le(a) in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. Serpa, J., Mesquita, P., Mendes, N., Oliveira, C., Almeida, R., Santos-Silva, F., Reis, C.A., Lependu, J., David, L. Cancer Lett. (2006)
- Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice. Tighe, H., Chen, P.P., Tucker, R., Kipps, T.J., Roudier, J., Jirik, F.R., Carson, D.A. J. Exp. Med. (1993)
- Analysis of Lewis fucosyltransferase genes from the human gastric mucosa of Lewis-positive and -negative individuals. Koda, Y., Kimura, H., Mekada, E. Blood (1993)
- Monoclonal antibodies against oncofetal mucin M1 antigens associated with precancerous colonic mucosae. Bara, J., Gautier, R., Daher, N., Zaghouani, H., Decaens, C. Cancer Res. (1986)
- Tumor necrosis factor alpha increases the expression of glycosyltransferases and sulfotransferases responsible for the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa. Delmotte, P., Degroote, S., Lafitte, J.J., Lamblin, G., Perini, J.M., Roussel, P. J. Biol. Chem. (2002)
- Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms. Cameron, H.S., Szczepaniak, D., Weston, B.W. J. Biol. Chem. (1995)
- Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19. Reguigne-Arnould, I., Couillin, P., Mollicone, R., Fauré, S., Fletcher, A., Kelly, R.J., Lowe, J.B., Oriol, R. Cytogenet. Cell Genet. (1995)
- Molecular basis of Lewis blood type in Taiwanese. Liu, T.C., Lin, S.F., Yang, T.Y., Perng, L.I., Jaung, S.J., Hu, C.Z., Chang, J.G. The Kaohsiung journal of medical sciences. (2000)
- Molecular genetics of alpha-L-fucosyltransferase genes (H, Se, Le, FUT4, FUT5 and FUT6). Mollicone, R., Candelier, J.J., Reguigne, I., Couillin, P., Fletcher, A., Oriol, R. Transfusion clinique et biologique : journal de la Société française de transfusion sanguine. (1994)
- Influence of Lewis alpha1-3/4-L-fucosyltransferase (FUT3) gene mutations on enzyme activity, erythrocyte phenotyping, and circulating tumor marker sialyl-Lewis a levels. Orntoft, T.F., Vestergaard, E.M., Holmes, E., Jakobsen, J.S., Grunnet, N., Mortensen, M., Johnson, P., Bross, P., Gregersen, N., Skorstengaard, K., Jensen, U.B., Bolund, L., Wolf, H. J. Biol. Chem. (1996)
- Transfection of alpha(1,3)fucosyltransferase antisense sequences impairs the proliferative and tumorigenic ability of human colon carcinoma cells. Hiller, K.M., Mayben, J.P., Bendt, K.M., Manousos, G.A., Senger, K., Cameron, H.S., Weston, B.W. Mol. Carcinog. (2000)
- Role of the Lewis(x) glycan determinant in corneal epithelial cell adhesion and differentiation. Cao, Z., Zhao, Z., Mohan, R., Alroy, J., Stanley, P., Panjwani, N. J. Biol. Chem. (2001)
- Activation of the immune system and systemic immune-complex deposits in Brown Norway rats with dental amalgam restorations. Hultman, P., Lindh, U., Hörsted-Bindslev, P. J. Dent. Res. (1998)
- Neuromagnetic indicators of auditory cortical reorganization of tinnitus. Weisz, N., Wienbruch, C., Dohrmann, K., Elbert, T. Brain (2005)
- The formation of the oncofetal J28 glycotope involves core-2 beta6-N-acetylglucosaminyltransferase and alpha3/4-fucosyltransferase activities. Panicot, L., Mas, E., Pasqualini, E., Zerfaoui, M., Lombardo, D., Sadoulet, M.O., El Battari, A. Glycobiology (1999)
- Biochemical characterization of Silene alba alpha4-fucosyltransferase and Lewis a products. Léonard, R., Lhernould, S., Carlué, M., Fleurat, P., Maftah, A., Costa, G. Glycoconj. J. (2005)
- Non-isosteric C-glycosyl analogues of natural nucleotide diphosphate sugars as glycosyltransferase inhibitors. Vidal, S., Bruyère, I., Malleron, A., Augé, C., Praly, J.P. Bioorg. Med. Chem. (2006)
- Regulation of sialyl-Lewis x epitope expression by TNF-alpha and EGF in an airway carcinoma cell line. Ishibashi, Y., Inouye, Y., Okano, T., Taniguchi, A. Glycoconj. J. (2005)
- Alteration of gibberellin response in transgenic tobacco plants which express a human Lewis fucosyltransferase. Joly, C., Maftah, A., Riou-Khamlichi, C. Plant Physiol. Biochem. (2004)
- Typing for the human lewis blood group system by quantitative fluorescence-activated flow cytometry: large differences in antigen presentation on erythrocytes between A(1), A(2), B, O phenotypes. Larson, G., Svensson, L., Hynsjö, L., Elmgren, A., Rydberg, L. Vox Sang. (1999)
- Cytogenetics, conserved synteny and evolution of chicken fucosyltransferase genes compared to human. Coullin, P., Crooijmans, R.P., Fillon, V., Mollicone, R., Groenen, M.A., Adrien-Dehais, C., Bernheim, A., Zoorob, R., Oriol, R., Candelier, J.J. Cytogenet. Genome Res. (2003)
- FUT4 and FUT9 genes are expressed early in human embryogenesis. Cailleau-Thomas, A., Coullin, P., Candelier, J.J., Balanzino, L., Mennesson, B., Oriol, R., Mollicone, R. Glycobiology (2000)
- Significance of individual point mutations, T202C and C314T, in the human Lewis (FUT3) gene for expression of Lewis antigens by the human alpha(1,3/1,4)-fucosyltransferase, Fuc-TIII. Elmgren, A., Mollicone, R., Costache, M., Börjeson, C., Oriol, R., Harrington, J., Larson, G. J. Biol. Chem. (1997)
- Determination of Lewis FUT3 gene mutations by PCR using sequence-specific primers enables efficient genotyping of clinical samples. Grahn, A., Elmgren, A., Aberg, L., Svensson, L., Jansson, P.A., Lönnroth, P., Larson, G. Hum. Mutat. (2001)
- Different expression levels of alpha3/4 fucosyltransferases and Lewis determinants in ovarian carcinoma tissues and cell lines. Escrevente, C., Machado, E., Brito, C., Reis, C.A., Stoeck, A., Runz, S., Marmé, A., Altevogt, P., Costa, J. Int. J. Oncol. (2006)