Gene Review:
Mc3r - melanocortin 3 receptor
Rattus norvegicus
Synonyms:
MC3-R, Melanocortin receptor 3
- Melanocortin antagonists define two distinct pathways of cardiovascular control by alpha- and gamma-melanocyte-stimulating hormones. Li, S.J., Varga, K., Archer, P., Hruby, V.J., Sharma, S.D., Kesterson, R.A., Cone, R.D., Kunos, G. J. Neurosci. (1996)
- Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding. Harrold, J.A., Widdowson, P.S., Williams, G. Diabetes (1999)
- Different cardiovascular profiles of three melanocortins in conscious rats; evidence for antagonism between gamma 2-MSH and ACTH-(1-24). Van Bergen, P., Kleijne, J.A., De Wildt, D.J., Versteeg, D.H. Br. J. Pharmacol. (1997)
- Role of central melanocortins in endotoxin-induced anorexia. Huang, Q.H., Hruby, V.J., Tatro, J.B. Am. J. Physiol. (1999)
- ACTH enhances chondrogenesis in multipotential progenitor cells and matrix production in chondrocytes. Evans, J.F., Niu, Q.T., Canas, J.A., Shen, C.L., Aloia, J.F., Yeh, J.K. Bone (2004)
- Melanocortin-4 receptor messenger RNA expression is up-regulated in the non-damaged striatum following unilateral hypoxic-ischaemic brain injury. Mountjoy, K.G., Guan, J., Elia, C.J., Sirimanne, E.S., Williams, C.E. Neuroscience (1999)
- Postnatal expression of melanocortin-3 receptor in rat diencephalon and mesencephalon. Xia, Y., Wikberg, J.E. Neuropharmacology (1997)
- Evidence that the effect of melanocortins on female sexual behavior in preoptic area is mediated by the MC3 receptor; Participation of nitric oxide. Nocetto, C., Cragnolini, A.B., Schiöth, H.B., Scimonelli, T.N. Behav. Brain Res. (2004)
- Investigation of the melanocyte stimulating hormones on food intake. Lack Of evidence to support a role for the melanocortin-3-receptor. Abbott, C.R., Rossi, M., Kim, M., AlAhmed, S.H., Taylor, G.M., Ghatei, M.A., Smith, D.M., Bloom, S.R. Brain Res. (2000)
- Expression of Melanocortin MC3 and MC4 Receptor mRNAs by Neuropeptide Y Neurons in the Rat Arcuate Nucleus. Mounien, L., Bizet, P., Boutelet, I., Vaudry, H., Jégou, S. Neuroendocrinology (2005)
- Evidence for the interaction of protein kinase C and melanocortin 3-receptor signaling pathways. Wachira, S.J., Hughes-Darden, C.A., Taylor, C.V., Ochillo, R., Robinson, T.J. Neuropeptides (2003)
- Neural melanocortin receptors are differentially expressed and regulated by stress in rat hypothalamic-pituitary-adrenal axis. Wachira, S.J., Hughes-Darden, C.A., Nicholas, H.B., Taylor, C.V., Robinson, T.J. Cell. Mol. Biol. (Noisy-le-grand) (2004)
- Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists. Ni, X.P., Kesterson, R.A., Sharma, S.D., Hruby, V.J., Cone, R.D., Wiedemann, E., Humphreys, M.H. Am. J. Physiol. (1998)
- Different developmental patterns of melanocortin MC3 and MC4 receptor mRNA: predominance of Mc4 in fetal rat nervous system. Kistler-Heer, V., Lauber, M.E., Lichtensteiger, W. J. Neuroendocrinol. (1998)
- Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain. Bagnol, D., Lu, X.Y., Kaelin, C.B., Day, H.E., Ollmann, M., Gantz, I., Akil, H., Barsh, G.S., Watson, S.J. J. Neurosci. (1999)
- Melanocortin-3 receptor mRNA expression in pro-opiomelanocortin neurones of the rat arcuate nucleus. Jégou, S., Boutelet, I., Vaudry, H. J. Neuroendocrinol. (2000)
- Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat. Haskell-Luevano, C., Chen, P., Li, C., Chang, K., Smith, M.S., Cameron, J.L., Cone, R.D. Endocrinology (1999)
- Evaluation of the role of melanocortin 3 and 4 receptors in leptin-stimulated and spontaneous growth hormone secretion in rats. Watanobe, H., Yoneda, M. Neuroendocrinology (2003)
- The role of central melanocortin receptors in the activation of the hypothalamus-pituitary-adrenal-axis and the induction of excessive grooming. Von Frijtag, J.C., Croiset, G., Gispen, W.H., Adan, R.A., Wiegant, V.M. Br. J. Pharmacol. (1998)
- Detection of melanocortin-3 receptor mRNA in immature rat pituitary: functional relation to gamma3-MSH-induced changes in intracellular Ca2+ concentration? Lorsignol, A., Vande Vijver, V., Ramaekers, D., Vankelecom, H., Denef, C. J. Neuroendocrinol. (1999)
- Modulation by dietary sodium intake of melanocortin 3 receptor mRNA and protein abundance in the rat kidney. Ni, X.P., Bhargava, A., Pearce, D., Humphreys, M.H. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2006)