Gene Review:
HCK - HCK proto-oncogene, Src family tyrosine...
Homo sapiens
Synonyms:
Hematopoietic cell kinase, Hemopoietic cell kinase, JTK9, Tyrosine-protein kinase HCK, p59-HCK/p60-HCK, ...
Donato,
Wu,
Stapley,
Gallick,
Lin,
Arlinghaus,
Talpaz,
Piccardoni,
Sideri,
Manarini,
Piccoli,
Martelli,
de Gaetano,
Cerletti,
Evangelista,
- Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells. Quintrell, N., Lebo, R., Varmus, H., Bishop, J.M., Pettenati, M.J., Le Beau, M.M., Diaz, M.O., Rowley, J.D. Mol. Cell. Biol. (1987)
- BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571. Donato, N.J., Wu, J.Y., Stapley, J., Gallick, G., Lin, H., Arlinghaus, R., Talpaz, M. Blood (2003)
- RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Arold, S., O'Brien, R., Franken, P., Strub, M.P., Hoh, F., Dumas, C., Ladbury, J.E. Biochemistry (1998)
- Corneal epithelial cells and stromal keratocytes efficently produce CC chemokine-ligand 20 (CCL20) and attract cells expressing its receptor CCR6 in mouse herpetic stromal keratitis. Shirane, J., Nakayama, T., Nagakubo, D., Izawa, D., Hieshima, K., Shimomura, Y., Yoshie, O. Curr. Eye Res. (2004)
- Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae. Robbins, S.M., Quintrell, N.A., Bishop, J.M. Mol. Cell. Biol. (1995)
- Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]. Mahajan, S., Ghosh, S., Sudbeck, E.A., Zheng, Y., Downs, S., Hupke, M., Uckun, F.M. J. Biol. Chem. (1999)
- The transcription factor Sp1 regulates the myeloid-specific expression of the human hematopoietic cell kinase (HCK) gene through binding to two adjacent GC boxes within the HCK promoter-proximal region. Hauses, M., Tönjes, R.R., Grez, M. J. Biol. Chem. (1998)
- Platelet/polymorphonuclear leukocyte adhesion: a new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin. Piccardoni, P., Sideri, R., Manarini, S., Piccoli, A., Martelli, N., de Gaetano, G., Cerletti, C., Evangelista, V. Blood (2001)
- Human protein-tyrosine kinase gene HCK: expression and structural analysis of the promoter region. Lichtenberg, U., Quintrell, N., Bishop, J.M. Oncogene (1992)
- Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF). Kubo, E., Fatma, N., Sharma, P., Shinohara, T., Chylack, L.T., Akagi, Y., Singh, D.P. J. Mol. Biol. (2002)
- Identification of three RFLPs at the HCK locus on chromosome 20. Hollings, P.E., Morrison, M.J., Wells, E., Crossen, P.E. Hum. Genet. (1994)
- Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes. Islam, S., Kermode, T., Sultana, D., Moskowitz, R.W., Mukhtar, H., Malemud, C.J., Goldberg, V.M., Haqqi, T.M. Osteoarthr. Cartil. (2001)
- Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin. Lu, H., Chang, D.J., Baratte, B., Meijer, L., Schulze-Gahmen, U. J. Med. Chem. (2005)
- The genomic locus of the human hemopoietic-specific cell protein tyrosine kinase (PTK)-encoding gene (HCK) confirms conservation of exon-intron structure among human PTKs of the src family. Hradetzky, D., Strebhardt, K., Rübsamen-Waigmann, H. Gene (1992)