Gene Review:
HLA-DQA2 - major histocompatibility complex, class II...
Homo sapiens
Synonyms:
DX alpha chain, DX-ALPHA, HLA class II histocompatibility antigen, DQ alpha 2 chain, HLA class II histocompatibility antigen, DQ(6) alpha chain, HLA-DQA1, ...
- A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus. Khalil, I., d'Auriol, L., Gobet, M., Morin, L., Lepage, V., Deschamps, I., Park, M.S., Degos, L., Galibert, F., Hors, J. J. Clin. Invest. (1990)
- Trans-encoded DQ alpha beta heterodimers confer susceptibility to myasthenia gravis disease. Khalil, I., Berrih-Aknin, S., Lepage, V., Loste, M.N., Gajdos, P., Hors, J., Charron, D., Degos, L. C. R. Acad. Sci. III, Sci. Vie (1993)
- Linkage disequilibrium between the HLA-DQA2 alleles and the HLA/DR/DQ complex. Ratanachaiyavong, S., Bidwell, J.L., Bidwell, E.A., McGregor, A.M. Hum. Immunol. (1991)
- Role of predisposing and protective HLA-DQA and HLA-DQB alleles in Sardinian multiple sclerosis. Marrosu, M.G., Muntoni, F., Murru, M.R., Costa, G., Congia, M., Marrosu, G., Aiello, I., Pirastu, M., Cianchetti, C. Arch. Neurol. (1993)
- Celiac disease is associated with an extended HLA-DR3 haplotype which includes HLA-DPw1. Hall, M.A., Lanchbury, J.S., Bolsover, W.J., Welsh, K.I., Ciclitira, P.J. Hum. Immunol. (1990)
- MHC class II sequences of an HLA-DR2 narcoleptic. Lock, C.B., So, A.K., Welsh, K.I., Parkes, J.D., Trowsdale, J. Immunogenetics (1988)
- Narcolepsy-cataplexy in Israeli Jews is associated exclusively with the HLA DR2 haplotype. A study at the serological and genomic level. Wilner, A., Steinman, L., Lavie, P., Peled, R., Friedmann, A., Brautbar, C. Hum. Immunol. (1988)
- Immunogenetic risk factors of dilated cardiomyopathy. Popovici, M., Groppa, L., Kalinina, L. Blood pressure. Supplement. (1996)
- Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition. Kwok, W.W., Mickelson, E., Masewicz, S., Milner, E.C., Hansen, J., Nepom, G.T. J. Exp. Med. (1990)
- Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. Sollid, L.M., Markussen, G., Ek, J., Gjerde, H., Vartdal, F., Thorsby, E. J. Exp. Med. (1989)
- HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants. Pious, D., Dixon, L., Levine, F., Cotner, T., Johnson, R. J. Exp. Med. (1985)
- HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus. Wang, H., He, R. Chin. Med. Sci. J. (1993)
- Limited polymorphism of the HLA-DQA2 promoter and identification of a variant octamer. Rudy, G., Lew, A.M. Hum. Immunol. (1994)
- A SINE insertion provides information on the divergence of the HLA-DQA1 and HLA-DQA2 genes. Del Pozzo, G., Guardiola, J. Immunogenetics (1990)
- A family study confirms that the HLA-DP associations with celiac disease are the result of an extended HLA-DR3 haplotype. Bolsover, W.J., Hall, M.A., Vaughan, R.W., Welsh, K.I., Ciclitira, P.J. Hum. Immunol. (1991)
- Strong association between DQA1/DQB1 genotype and early-onset IDDM in Chinese: the association is with alleles rather than specific residues. Chang, Y.W., Lam, K.S., Hawkins, B.R. Eur. J. Immunogenet. (1998)
- The cryptic HLA-DQA2 ("DX alpha") gene is expressed in human B cell lines. Yu, L.P., Sheehy, M.J. J. Immunol. (1991)
- Particular HLA-DQ alpha beta heterodimer associated with IDDM susceptibility in both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites. Rønningen, K.S., Gjertsen, H.A., Iwe, T., Spurkland, A., Hansen, T., Thorsby, E. Diabetes (1991)
- Co-amplification of the cystic fibrosis delta F508 mutation with the HLA DQA1 sequence in single cell PCR: implications for improved assessment of polar bodies and blastomeres in preimplantation diagnosis. Wu, R., Cuppens, H., Buyse, I., Decorte, R., Marynen, P., Gordts, S., Cassiman, J.J. Prenat. Diagn. (1993)
- HLA DQ and DP locus mismatches and their effect on MLC in HLA class I- and DRB1-matched unrelated patient/donor pairs waiting for allogeneic bone-marrow transplantation. Partanen, J., Koskimies, S. Scand. J. Immunol. (1994)
- HLA-DQA1 and DQB1 gene polymorphisms in type I diabetic patients from central Italy and their use for risk prediction. Buzzetti, R., Nisticò, L., Osborn, J.F., Giovannini, C., Chersi, A., Sorrentino, R. Diabetes (1993)
- Analysis of HLA-class II DQA1, DQB1, DRB1 and DPB1 in Italian multiple sclerosis patients. Ciusani, E., Allen, M., Sandberg-Wollheim, M., Eoli, M., Salmaggi, A., Milanese, C., Nespolo, A., Gyllensten, U. Eur. J. Immunogenet. (1995)
- Immunologic aspects of scleroderma. White, B. Current opinion in rheumatology. (1994)
- The role of genetic predisposition to type I (insulin-dependent) diabetes mellitus. Deschamps, I., Beressi, J.P., Khalil, I., Robert, J.J., Hors, J. Ann. Med. (1991)
- Distributions of HLA class II alleles in autoantibody subsets among Norwegian patients with systemic lupus erythematosus. Skarsvåg, S., Hansen, K.E., Moen, T., Eggen, B.M. Scand. J. Immunol. (1995)
- T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer. Lundin, K.E., Sollid, L.M., Qvigstad, E., Markussen, G., Gjertsen, H.A., Ek, J., Thorsby, E. J. Immunol. (1990)
- A genetically controlled pairing anomaly between HLA-DQ alpha and HLA-DQ beta chains. Kwok, W.W., Thurtle, P., Nepom, G.T. J. Immunol. (1989)
- Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Rønningen, K.S., Spurkland, A., Iwe, T., Vartdal, F., Thorsby, E. Tissue Antigens (1991)
- Ancient roots for polymorphism at the HLA-DQ alpha locus in primates. Gyllensten, U.B., Erlich, H.A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Olerup, O., Hillert, J. Tissue Antigens (1991)
- Nucleotide sequence, polymorphism, and evolution of ovine MHC class II DQA genes. Scott, P.C., Gogolin-Ewens, K.J., Adams, T.E., Brandon, M.R. Immunogenetics (1991)
- Time-resolved fluorometry based sandwich hybridisation assay for HLA-DQA1 typing. Sjöroos, M., Ilonen, J., Reijonen, H., Lövgren, T. Dis. Markers (1998)
- Influence of post-mortem changes on DNA typing (D1S80, TH01, HLA DQA 1, and PM typing system): case studies for personal identification. Fujita, Y., Kubo, S., Tokunaga, I., Kitamura, O., Gotohda, T., Ishigami, A. Legal medicine (Tokyo, Japan) (2004)
- HLA-DQA1 allele typing by nonisotopic PCR-LIS-SSCP. Abba, M.C., Gómez, M.A., Golijow, C.D. Braz. J. Med. Biol. Res. (2001)