Gene Review:
HSD17B4 - hydroxysteroid (17-beta) dehydrogenase 4
Homo sapiens
Synonyms:
17-beta-HSD 4, 17-beta-hydroxysteroid dehydrogenase 4, D-bifunctional protein, DBP, EDH17B4, ...
- D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: a newly identified peroxisomal disorder. Suzuki, Y., Jiang, L.L., Souri, M., Miyazawa, S., Fukuda, S., Zhang, Z., Une, M., Shimozawa, N., Kondo, N., Orii, T., Hashimoto, T. Am. J. Hum. Genet. (1997)
- Clinical and biochemical spectrum of D-bifunctional protein deficiency. Ferdinandusse, S., Denis, S., Mooyer, P.A., Dekker, C., Duran, M., Soorani-Lunsing, R.J., Boltshauser, E., Macaya, A., Gärtner, J., Majoie, C.B., Barth, P.G., Wanders, R.J., Poll-The, B.T. Ann. Neurol. (2006)
- Racial disparities in the association between birth weight in the term infant and blood pressure at age 7 years: results from the collaborative perinatal project. Hemachandra, A.H., Klebanoff, M.A., Furth, S.L. J. Am. Soc. Nephrol. (2006)
- Delapril/manidipine. McCormack, P.L., Keating, G.M. Drugs (2006)
- Effects of phthalate esters on the sensitization phase of contact hypersensitivity induced by fluorescein isothiocyanate. Imai, Y., Kondo, A., Iizuka, H., Maruyama, T., Kurohane, K. Clin. Exp. Allergy (2006)
- Is high job strain associated with hypertension genesis? Ducher, M., Cerutti, C., Chatellier, G., Fauvel, J.P. Am. J. Hypertens. (2006)
- Degradation of di-n-butyl phthalate using photoreactor packed with TiO(2) immobilized on glass beads. Chiou, C.S., Shie, J.L., Chang, C.Y., Liu, C.C., Chang, C.T. J. Hazard. Mater. (2006)
- Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency. van Grunsven, E.G., van Berkel, E., Ijlst, L., Vreken, P., de Klerk, J.B., Adamski, J., Lemonde, H., Clayton, P.T., Cuebas, D.A., Wanders, R.J. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Enoyl-CoA hydratase deficiency: identification of a new type of D-bifunctional protein deficiency. van Grunsven, E.G., Mooijer, P.A., Aubourg, P., Wanders, R.J. Hum. Mol. Genet. (1999)
- Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Fiegl, H., Millinger, S., Goebel, G., Müller-Holzner, E., Marth, C., Laird, P.W., Widschwendter, M. Cancer Res. (2006)
- Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis. Su, H.M., Moser, A.B., Moser, H.W., Watkins, P.A. J. Biol. Chem. (2001)
- Effects of phthalate esters on dendritic cell subsets and interleukin-4 production in fluorescein isothiocyanate-induced contact hypersensitivity. Maruyama, T., Shiba, T., Iizuka, H., Matsuda, T., Kurohane, K., Imai, Y. Microbiol. Immunol. (2007)
- Characterization of the HSD17B4 gene: D-specific multifunctional protein 2/17beta-hydroxysteroid dehydrogenase IV. Möller, G., Leenders, F., van Grunsven, E.G., Dolez, V., Qualmann, B., Kessels, M.M., Markus, M., Krazeisen, A., Husen, B., Wanders, R.J., de Launoit, Y., Adamski, J. J. Steroid Biochem. Mol. Biol. (1999)
- Peroxisome targeting of porcine 17beta-hydroxysteroid dehydrogenase type IV/D-specific multifunctional protein 2 is mediated by its C-terminal tripeptide AKI. Möller, G., Lüders, J., Markus, M., Husen, B., Van Veldhoven, P.P., Adamski, J. J. Cell. Biochem. (1999)
- Regulation of peroxisome size and number by fatty acid beta -oxidation in the yeast yarrowia lipolytica. Smith, J.J., Brown, T.W., Eitzen, G.A., Rachubinski, R.A. J. Biol. Chem. (2000)
- Yeast peroxisomal multifunctional enzyme: (3R)-hydroxyacyl-CoA dehydrogenase domains A and B are required for optimal growth on oleic acid. Qin, Y.M., Marttila, M.S., Haapalainen, A.M., Siivari, K.M., Glumoff, T., Hiltunen, J.K. J. Biol. Chem. (1999)
- Physiological role of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein. Jiang, L.L., Kurosawa, T., Sato, M., Suzuki, Y., Hashimoto, T. J. Biochem. (1997)
- Expression and regulation of aromatase and 17 beta-hydroxysteroid dehydrogenase type 4 in human THP 1 leukemia cells. Jakob, F., Homann, D., Adamski, J. J. Steroid Biochem. Mol. Biol. (1995)
- Association of blood pressure status with the optic disk structure in non-glaucoma subjects: the Thessaloniki eye study. Topouzis, F., Coleman, A.L., Harris, A., Jonescu-Cuypers, C., Yu, F., Mavroudis, L., Anastasopoulos, E., Pappas, T., Koskosas, A., Wilson, M.R. Am. J. Ophthalmol. (2006)
- Unique multifunctional HSD17B4 gene product: 17beta-hydroxysteroid dehydrogenase 4 and D-3-hydroxyacyl-coenzyme A dehydrogenase/hydratase involved in Zellweger syndrome. de Launoit, Y., Adamski, J. J. Mol. Endocrinol. (1999)
- Crystal structure of the liganded SCP-2-like domain of human peroxisomal multifunctional enzyme type 2 at 1.75 A resolution. Haapalainen, A.M., van Aalten, D.M., Meriläinen, G., Jalonen, J.E., Pirilä, P., Wierenga, R.K., Hiltunen, J.K., Glumoff, T. J. Mol. Biol. (2001)
- Sensitive analysis of serum 3alpha, 7alpha, 12alpha,24-tetrahydroxy- 5beta-cholestan-26-oic acid diastereomers using gas chromatography-mass spectrometry and its application in peroxisomal D-bifunctional protein deficiency. Vreken, P., van Rooij, A., Denis, S., van Grunsven, E.G., Cuebas, D.A., Wanders, R.J. J. Lipid Res. (1998)
- Radical production and cytotoxic activity of tert-butyl-substituted phenols. Saito, M., Atsumi, T., Satoh, K., Ishihara, M., Iwakura, I., Sakagami, H., Yokoe, I., Fujisawa, S. In vitro & molecular toxicology. (2001)
- A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Jobling, S., Reynolds, T., White, R., Parker, M.G., Sumpter, J.P. Environ. Health Perspect. (1995)
- Twenty-Four-Hour Ambulatory BP in Snoring Children With Obstructive Sleep Apnea Syndrome. Leung, L.C., Ng, D.K., Lau, M.W., Chan, C.H., Kwok, K.L., Chow, P.Y., Cheung, J.M. Chest (2006)
- Molecular analysis of genomic DNA allows rapid, and accurate, prenatal diagnosis of peroxisomal D-bifunctional protein deficiency. Paton, B.C., Solly, P.B., Nelson, P.V., Pollard, A.N., Sharp, P.C., Fietz, M.J. Prenat. Diagn. (2002)
- Vitamin D-binding protein (DBP) gene polymorphism is associated with Graves' disease and the vitamin D status in a Polish population study. Kurylowicz, A., Ramos-Lopez, E., Bednarczuk, T., Badenhoop, K. Exp. Clin. Endocrinol. Diabetes (2006)
- Bile acid profiles in a peroxisomal D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency. Une, M., Konishi, M., Suzuki, Y., Akaboshi, S., Yoshii, M., Kuramoto, T., Fujimura, K. J. Biochem. (1997)
- Dietary and lifestyle factors associated with blood pressure among U.S. adolescents. Sugiyama, T., Xie, D., Graham-Maar, R.C., Inoue, K., Kobayashi, Y., Stettler, N. The Journal of adolescent health : official publication of the Society for Adolescent Medicine (2007)