Gene Review:
PHF1 - PHD finger protein 1
Homo sapiens
Synonyms:
MTF2L2, PCL1, PHF2, Polycomb-like protein 1, Protein PHF1, ...
Wei,
Holzer,
Brueckner,
Liu,
Arendt,
Schultz,
Ghebremedhin,
Del Tredici,
Rüb,
Braak,
Mellor,
Scott,
Heino,
Peterson,
Mittaz,
Lalioti,
Betterle,
Cohen,
Seri,
Lerone,
Romeo,
Collin,
Salo,
Metcalfe,
Weetman,
Papasavvas,
Rossier,
Nagamine,
Kudoh,
Shimizu,
Krohn,
Antonarakis,
Micci,
Panagopoulos,
Bjerkehagen,
Heim,
- Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein-Taybi syndrome. Kalkhoven, E., Roelfsema, J.H., Teunissen, H., den Boer, A., Ariyurek, Y., Zantema, A., Breuning, M.H., Hennekam, R.C., Peters, D.J. Hum. Mol. Genet. (2003)
- The yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone h3. Martin, D.G., Baetz, K., Shi, X., Walter, K.L., Macdonald, V.E., Wlodarski, M.J., Gozani, O., Hieter, P., Howe, L. Mol. Cell. Biol. (2006)
- Reversible heat stress-related loss of phosphorylated Alzheimer-type epitopes in Tau proteins of human neuroblastoma cells. Chiang, M.F., Liu, W.K., Yen, S.H. J. Neurosci. (1993)
- Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription. Shamay, M., Barak, O., Doitsh, G., Ben-Dor, I., Shaul, Y. J. Biol. Chem. (2002)
- It takes a PHD to read the histone code. Mellor, J. Cell (2006)
- The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Gozani, O., Karuman, P., Jones, D.R., Ivanov, D., Cha, J., Lugovskoy, A.A., Baird, C.L., Zhu, H., Field, S.J., Lessnick, S.L., Villasenor, J., Mehrotra, B., Chen, J., Rao, V.R., Brugge, J.S., Ferguson, C.G., Payrastre, B., Myszka, D.G., Cantley, L.C., Wagner, G., Divecha, N., Prestwich, G.D., Yuan, J. Cell (2003)
- Positional cloning of the APECED gene. Nagamine, K., Peterson, P., Scott, H.S., Kudoh, J., Minoshima, S., Heino, M., Krohn, K.J., Lalioti, M.D., Mullis, P.E., Antonarakis, S.E., Kawasaki, K., Asakawa, S., Ito, F., Shimizu, N. Nat. Genet. (1997)
- Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. Schultz, D.C., Friedman, J.R., Rauscher, F.J. Genes Dev. (2001)
- Alzheimer's-associated phospho-tau epitope in human neuroblastoma cell cultures: up-regulation by fibronectin and laminin. Martin, H., Lambert, M.P., Barber, K., Hinton, S., Klein, W.L. Neuroscience (1995)
- Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. Gómez-Ramos, A., Díaz-Nido, J., Smith, M.A., Perry, G., Avila, J. J. Neurosci. Res. (2003)
- Consistent rearrangement of chromosomal band 6p21 with generation of fusion genes JAZF1/PHF1 and EPC1/PHF1 in endometrial stromal sarcoma. Micci, F., Panagopoulos, I., Bjerkehagen, B., Heim, S. Cancer Res. (2006)
- Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid. Bloom, G.S., Ren, K., Glabe, C.G. Biochim. Biophys. Acta (2005)
- Yng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFs. Taverna, S.D., Ilin, S., Rogers, R.S., Tanny, J.C., Lavender, H., Li, H., Baker, L., Boyle, J., Blair, L.P., Chait, B.T., Patel, D.J., Aitchison, J.D., Tackett, A.J., Allis, C.D. Mol. Cell (2006)
- Localization of transglutaminase in hippocampal neurons: implications for Alzheimer's disease. Appelt, D.M., Kopen, G.C., Boyne, L.J., Balin, B.J. J. Histochem. Cytochem. (1996)
- Dephosphorylation of tau protein by calcineurin triturated into neural living cells. Wei, Q., Holzer, M., Brueckner, M.K., Liu, Y., Arendt, T. Cell. Mol. Neurobiol. (2002)
- Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology. Anderson, A.J., Cummings, B.J., Cotman, C.W. Exp. Neurol. (1994)
- Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease. Xia, M., Qin, S., McNamara, M., Mackay, C., Hyman, B.T. Am. J. Pathol. (1997)
- Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins. Scott, H.S., Heino, M., Peterson, P., Mittaz, L., Lalioti, M.D., Betterle, C., Cohen, A., Seri, M., Lerone, M., Romeo, G., Collin, P., Salo, M., Metcalfe, R., Weetman, A., Papasavvas, M.P., Rossier, C., Nagamine, K., Kudoh, J., Shimizu, N., Krohn, K.J., Antonarakis, S.E. Mol. Endocrinol. (1998)
- NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease. Bottomley, M.J., Stier, G., Pennacchini, D., Legube, G., Simon, B., Akhtar, A., Sattler, M., Musco, G. J. Biol. Chem. (2005)
- Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1. Moosmann, P., Georgiev, O., Le Douarin, B., Bourquin, J.P., Schaffner, W. Nucleic Acids Res. (1996)
- Optimization of techniques for the maximal detection and quantification of Alzheimer's-related neuropathology with digital imaging. Cummings, B.J., Mason, A.J., Kim, R.C., Sheu, P.C., Anderson, A.J. Neurobiol. Aging (2002)
- Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404. Otvos, L., Feiner, L., Lang, E., Szendrei, G.I., Goedert, M., Lee, V.M. J. Neurosci. Res. (1994)
- Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells. Wang, Y.P., Wang, X.C., Tian, Q., Yang, Y., Zhang, Q., Zhang, J.Y., Zhang, Y.C., Wang, Z.F., Wang, Q., Li, H., Wang, J.Z. Journal of neural transmission (Vienna, Austria : 1996) (2006)
- c-jun N-terminal kinase hyperphosphorylates R406W tau at the PHF-1 site during mitosis. Tatebayashi, Y., Planel, E., Chui, D.H., Sato, S., Miyasaka, T., Sahara, N., Murayama, M., Kikuchi, N., Yoshioka, K., Rivka, R., Takashima, A. FASEB J. (2006)
- Polycomblike PHD fingers mediate conserved interaction with enhancer of zeste protein. O'Connell, S., Wang, L., Robert, S., Jones, C.A., Saint, R., Jones, R.S. J. Biol. Chem. (2001)
- The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases. Mawal-Dewan, M., Henley, J., Van de Voorde, A., Trojanowski, J.Q., Lee, V.M. J. Biol. Chem. (1994)
- PHF3-specific antibody responses in over 60% of patients with glioblastoma multiforme. Struss, A.K., Romeike, B.F., Munnia, A., Nastainczyk, W., Steudel, W.I., König, J., Ohgaki, H., Feiden, W., Fischer, U., Meese, E. Oncogene (2001)
- MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia. Emerling, B.M., Bonifas, J., Kratz, C.P., Donovan, S., Taylor, B.R., Green, E.D., Le Beau, M.M., Shannon, K.M. Oncogene (2002)
- PHF2, a novel PHD finger gene located on human chromosome 9q22. Hasenpusch-Theil, K., Chadwick, B.P., Theil, T., Heath, S.K., Wilkinson, D.G., Frischauf, A.M. Mamm. Genome (1999)
- The identification and localization of a human gene with sequence similarity to Polycomblike of Drosophila melanogaster. Coulson, M., Robert, S., Eyre, H.J., Saint, R. Genomics (1998)
- Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Spillantini, M.G., Crowther, R.A., Goedert, M. Acta Neuropathol. (1996)
- Cell cycle-dependent phosphorylation and microtubule binding of tau protein stably transfected into Chinese hamster ovary cells. Preuss, U., Döring, F., Illenberger, S., Mandelkow, E.M. Mol. Biol. Cell (1995)
- High prevalence of thorn-shaped astrocytes in the aged human medial temporal lobe. Schultz, C., Ghebremedhin, E., Del Tredici, K., Rüb, U., Braak, H. Neurobiol. Aging (2004)