Gene Review:
TNFSF4 - tumor necrosis factor (ligand) superfamily...
Homo sapiens
Synonyms:
CD134L, CD252, GP34, Glycoprotein Gp34, OX-40L, ...
Cerutti,
Kim,
Shah,
Schattner,
Zan,
Schaffer,
Casali,
Biagi,
Dotti,
Yvon,
Lee,
Pule,
Vigouroux,
Gottschalk,
Popat,
Rousseau,
Brenner,
Wang,
Ria,
Kelmenson,
Eriksson,
Higgins,
Samnegård,
Petros,
Rollins,
Bennet,
Wiman,
de Faire,
Wennberg,
Olsson,
Ishii,
Sugamura,
Hamsten,
Forsman-Semb,
Lagercrantz,
Paigen,
- Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Wang, X., Ria, M., Kelmenson, P.M., Eriksson, P., Higgins, D.C., Samnegård, A., Petros, C., Rollins, J., Bennet, A.M., Wiman, B., de Faire, U., Wennberg, C., Olsson, P.G., Ishii, N., Sugamura, K., Hamsten, A., Forsman-Semb, K., Lagercrantz, J., Paigen, B. Nat. Genet. (2005)
- Expression of gp34 (OX40 ligand) and OX40 on human T cell clones. Takasawa, N., Ishii, N., Higashimura, N., Murata, K., Tanaka, Y., Nakamura, M., Sasaki, T., Sugamura, K. Jpn. J. Cancer Res. (2001)
- Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax. Miura, S., Ohtani, K., Numata, N., Niki, M., Ohbo, K., Ina, Y., Gojobori, T., Tanaka, Y., Tozawa, H., Nakamura, M. Mol. Cell. Biol. (1991)
- OX40 expressed on fresh leukemic cells from adult T-cell leukemia patients mediates cell adhesion to vascular endothelial cells: implication for the possible involvement of OX40 in leukemic cell infiltration. Imura, A., Hori, T., Imada, K., Kawamata, S., Tanaka, Y., Imamura, S., Uchiyama, T. Blood (1997)
- Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein. Higgins, L.M., McDonald, S.A., Whittle, N., Crockett, N., Shields, J.G., MacDonald, T.T. J. Immunol. (1999)
- Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells. Cerutti, A., Kim, E.C., Shah, S., Schattner, E.J., Zan, H., Schaffer, A., Casali, P. Nat. Immunol. (2001)
- TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. Ito, T., Wang, Y.H., Duramad, O., Hori, T., Delespesse, G.J., Watanabe, N., Qin, F.X., Yao, Z., Cao, W., Liu, Y.J. J. Exp. Med. (2005)
- Identification of rat OX40 ligand by molecular cloning. Akiba, H., Atsuta, M., Yagita, H., Okumura, K. Biochem. Biophys. Res. Commun. (1998)
- Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand. Dannull, J., Nair, S., Su, Z., Boczkowski, D., DeBeck, C., Yang, B., Gilboa, E., Vieweg, J. Blood (2005)
- T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells. Kashiwakura, J., Yokoi, H., Saito, H., Okayama, Y. J. Immunol. (2004)
- Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor. Godfrey, W.R., Fagnoni, F.F., Harara, M.A., Buck, D., Engleman, E.G. J. Exp. Med. (1994)
- Molecular transfer of CD40 and OX40 ligands to leukemic human B cells induces expansion of autologous tumor-reactive cytotoxic T lymphocytes. Biagi, E., Dotti, G., Yvon, E., Lee, E., Pule, M., Vigouroux, S., Gottschalk, S., Popat, U., Rousseau, R., Brenner, M. Blood (2005)
- Expression and function of OX40 ligand on human dendritic cells. Ohshima, Y., Tanaka, Y., Tozawa, H., Takahashi, Y., Maliszewski, C., Delespesse, G. J. Immunol. (1997)
- OX40 ligand shuts down IL-10-producing regulatory T cells. Ito, T., Wang, Y.H., Duramad, O., Hanabuchi, S., Perng, O.A., Gilliet, M., Qin, F.X., Liu, Y.J. Proc. Natl. Acad. Sci. U.S.A. (2006)
- CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40-ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles. Brocker, T., Gulbranson-Judge, A., Flynn, S., Riedinger, M., Raykundalia, C., Lane, P. Eur. J. Immunol. (1999)
- Ligand-induced association between the T-cell antigen receptor and two glycoproteins. Fraser, J.D., Goldsmith, M.A., Weiss, A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Signaling of gp34 (OX40 ligand) induces vascular endothelial cells to produce a CC chemokine RANTES/CCL5. Kotani, A., Hori, T., Matsumura, Y., Uchiyama, T. Immunol. Lett. (2002)
- Nitric oxide inhibits IFN-alpha production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway. Morita, R., Uchiyama, T., Hori, T. J. Immunol. (2005)
- A recombinant vector expressing transgenes for four T-cell costimulatory molecules (OX40L, B7-1, ICAM-1, LFA-3) induces sustained CD4+ and CD8+ T-cell activation, protection from apoptosis, and enhanced cytokine production. Grosenbach, D.W., Schlom, J., Gritz, L., Gómez Yafal, A., Hodge, J.W. Cell. Immunol. (2003)
- Detection and characterization of OX40 ligand expression in human airway smooth muscle cells: a possible role in asthma? Burgess, J.K., Carlin, S., Pack, R.A., Arndt, G.M., Au, W.W., Johnson, P.R., Black, J.L., Hunt, N.H. J. Allergy Clin. Immunol. (2004)
- Plasmacytoid dendritic cells regulate Th cell responses through OX40 ligand and type I IFNs. Ito, T., Amakawa, R., Inaba, M., Hori, T., Ota, M., Nakamura, K., Takebayashi, M., Miyaji, M., Yoshimura, T., Inaba, K., Fukuhara, S. J. Immunol. (2004)