Gene Review:
CD58 - CD58 molecule
Homo sapiens
Synonyms:
Ag3, LFA-3, LFA3, Lymphocyte function-associated antigen 3, Surface glycoprotein LFA-3, ...
- Differential expression of cell adhesion molecules CD54/CD11a and CD58/CD2 by human melanoma cells and functional role in their interaction with cytotoxic cells. Altomonte, M., Gloghini, A., Bertola, G., Gasparollo, A., Carbone, A., Ferrone, S., Maio, M. Cancer Res. (1993)
- Expression of accessory molecules for T-cell activation in peripheral nerve of patients with CIDP and vasculitic neuropathy. Van Rhijn, I., Van den Berg, L.H., Bosboom, W.M., Otten, H.G., Logtenberg, T. Brain (2000)
- Gene structure, promoter characterization, and basis for alternative mRNA splicing of the human CD58 gene. Wallich, R., Brenner, C., Brand, Y., Roux, M., Reister, M., Meuer, S. J. Immunol. (1998)
- CD58 (LFA-3) stimulation provides a signal for human isotype switching and IgE production distinct from CD40. Diaz-Sanchez, D., Chegini, S., Zhang, K., Saxon, A. J. Immunol. (1994)
- Lineage-negative human leukocyte antigen-DR+ cells with the phenotype of undifferentiated dendritic cells in patients with carcinoma of the abdomen and pelvis. Melichar, B., Savary, C., Kudelka, A.P., Verschraegen, C., Kavanagh, J.J., Edwards, C.L., Platsoucas, C.D., Freedman, R.S. Clin. Cancer Res. (1998)
- Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Dustin, M.L., Springer, T.A. Annu. Rev. Immunol. (1991)
- The dendritic cell system and its role in immunogenicity. Steinman, R.M. Annu. Rev. Immunol. (1991)
- CD2-mediated adhesion facilitates T lymphocyte antigen recognition function. Moingeon, P., Chang, H.C., Wallner, B.P., Stebbins, C., Frey, A.Z., Reinherz, E.L. Nature (1989)
- The reduced expression of HLA-class II antigens and adhesion molecules on monocyte surface after phagocytosis of bacteria. Baran, J., Pryjma, J. Arch. Immunol. Ther. Exp. (Warsz.) (1994)
- The structural biology of CD2. Moingeon, P., Chang, H.C., Sayre, P.H., Clayton, L.K., Alcover, A., Gardner, P., Reinherz, E.L. Immunol. Rev. (1989)
- IL-4 induces LFA-1 and LFA-3 expression on Burkitt's lymphoma cell lines. Requirement of additional activation by phorbol myristate acetate for induction of homotypic cell adhesions. Rousset, F., Billaud, M., Blanchard, D., Figdor, C., Lenoir, G.M., Spits, H., De Vries, J.E. J. Immunol. (1989)
- Loss of alpha 1 beta 1 and reduced expression of other beta 1 integrins and CAM in lung adenocarcinoma compared with pneumocytes. Roussel, E., Gingras, M.C., Ro, J.Y., Branch, C., Roth, J.A. Journal of surgical oncology. (1994)
- Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59. Hahn, W.C., Menu, E., Bothwell, A.L., Sims, P.J., Bierer, B.E. Science (1992)
- Conformation and function of the N-linked glycan in the adhesion domain of human CD2. Wyss, D.F., Choi, J.S., Li, J., Knoppers, M.H., Willis, K.J., Arulanandam, A.R., Smolyar, A., Reinherz, E.L., Wagner, G. Science (1995)
- Polarized expression and function of the costimulatory molecule CD58 on human intestinal epithelial cells. Framson, P.E., Cho, D.H., Lee, L.Y., Hershberg, R.M. Gastroenterology (1999)
- Adhesion molecules on freshly recovered T leukemias promote tumor-directed lympholysis. Schirren, C.A., Völpel, H., Meuer, S.C. Blood (1992)
- Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoforms. Hamann, D., Baars, P.A., Hooibrink, B., van Lier, R.W. Blood (1996)
- Amino acid residues required for binding of lymphocyte function-associated antigen 3 (CD58) to its counter-receptor CD2. Osborn, L., Day, E.S., Miller, G.T., Karpusas, M., Tizard, R., Meuer, S.C., Hochman, P.S. J. Exp. Med. (1995)
- Mutational analysis of the CD2/CD58 interaction: the binding site for CD58 lies on one face of the first domain of human CD2. Somoza, C., Driscoll, P.C., Cyster, J.G., Williams, A.F. J. Exp. Med. (1993)
- The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC'C" face of the human CD2 adhesion domain. Arulanandam, A.R., Withka, J.M., Wyss, D.F., Wagner, G., Kister, A., Pallai, P., Recny, M.A., Reinherz, E.L. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Aplastic anemia and paroxysmal nocturnal hemoglobinuria: search for a pathogenetic link. Griscelli-Bennaceur, A., Gluckman, E., Scrobohaci, M.L., Jonveaux, P., Vu, T., Bazarbachi, A., Carosella, E.D., Sigaux, F., Socié, G. Blood (1995)
- Interaction between human CD2 and CD58 involves the major beta sheet surface of each of their respective adhesion domains. Arulanandam, A.R., Kister, A., McGregor, M.J., Wyss, D.F., Wagner, G., Reinherz, E.L. J. Exp. Med. (1994)
- The glycosylphosphatidylinositol-anchored form and the transmembrane form of CD58 associate with protein kinases. Itzhaky, D., Raz, N., Hollander, N. J. Immunol. (1998)
- Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. Hahn, W.C., Burakoff, S.J., Bierer, B.E. J. Immunol. (1993)
- Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot". Kim, M., Sun, Z.Y., Byron, O., Campbell, G., Wagner, G., Wang, J., Reinherz, E.L. J. Mol. Biol. (2001)
- Regulation of the IL-10 production by human T cells. Rafiq, K., Charitidou, L., Bullens, D.M., Kasran, A., Lorré, K., Ceuppens, J., van Gool, S.W. Scand. J. Immunol. (2001)
- Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding. Parra, E., Varga, M., Hedlund, G., Kalland, T., Dohlsten, M. Mol. Cell. Biol. (1997)
- Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3. Wolff, H.L., Burakoff, S.J., Bierer, B.E. J. Immunol. (1990)
- T cell activation pathways: B7, LFA-3, and ICAM-1 shape unique T cell profiles. Wingren, A.G., Parra, E., Varga, M., Kalland, T., Sjögren, H.O., Hedlund, G., Dohlsten, M. Crit. Rev. Immunol. (1995)
- Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes. Hahn, W.C., Rosenstein, Y., Burakoff, S.J., Bierer, B.E. J. Immunol. (1991)
- CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation. Menu, E., Tsai, B.C., Bothwell, A.L., Sims, P.J., Bierer, B.E. J. Immunol. (1994)
- Costimulation of human CD4+ T lymphocytes with B7 and lymphocyte function-associated antigen-3 results in distinct cell activation profiles. Parra, E., Wingren, A.G., Hedlund, G., Björklund, M., Sjögren, H.O., Kalland, T., Sansom, D., Dohlsten, M. J. Immunol. (1994)
- The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3. Selvaraj, P., Plunkett, M.L., Dustin, M., Sanders, M.E., Shaw, S., Springer, T.A. Nature (1987)
- A soluble multimeric recombinant CD2 protein identifies CD48 as a low affinity ligand for human CD2: divergence of CD2 ligands during the evolution of humans and mice. Arulanandam, A.R., Moingeon, P., Concino, M.F., Recny, M.A., Kato, K., Yagita, H., Koyasu, S., Reinherz, E.L. J. Exp. Med. (1993)
- Expression of surface adhesion molecules CD54 (ICAM-1) and CD58 (LFA-3) in adult acute leukemia: relationship with initial characteristics and prognosis. Archimbaud, E., Thomas, X., Campos, L., Magaud, J.P., Doré, J.F., Fiere, D. Leukemia (1992)
- Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1. Kingsmore, S.F., Souryal, C.A., Watson, M.L., Patel, D.D., Seldin, M.F. Immunogenetics (1995)
- Generation of functional and mature dendritic cells from cord blood and bone marrow CD34+ cells by two-step culture combined with calcium ionophore treatment. Liu, A., Takahashi, M., Narita, M., Zheng, Z., Kanazawa, N., Abe, T., Nikkuni, K., Furukawa, T., Toba, K., Fuse, I., Aizawa, Y. J. Immunol. Methods (2002)
- Expression of glycosyl-phosphatidylinositol-linked glycoproteins in blood cells from paroxysmal nocturnal haemoglobinuria patients: a flow cytometry study using CD55, CD58 and CD59 monoclonal antibodies. Navenot, J.M., Bernard, D., Harousseau, J.L., Muller, J.Y., Blanchard, D. Leuk. Lymphoma (1996)