Gene Review:
Akap12 - A kinase (PRKA) anchor protein (gravin) 12
Mus musculus
Synonyms:
A-kinase anchor protein 12, AI317366, AKAP-12, Gag12, Germ cell lineage protein gercelin, ...
- The Src-suppressed C kinase substrate, SSeCKS, is a potential metastasis inhibitor in prostate cancer. Xia, W., Unger, P., Miller, L., Nelson, J., Gelman, I.H. Cancer Res. (2001)
- SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Lee, S.W., Kim, W.J., Choi, Y.K., Song, H.S., Son, M.J., Gelman, I.H., Kim, Y.J., Kim, K.W. Nat. Med. (2003)
- SSeCKS, a major protein kinase C substrate with tumor suppressor activity, regulates G(1)-->S progression by controlling the expression and cellular compartmentalization of cyclin D. Lin, X., Nelson, P., Gelman, I.H. Mol. Cell. Biol. (2000)
- v-Jun targets showing an expression pattern that correlates with the transformed cellular phenotype. Iacovoni, J.S., Cohen, S.B., Berg, T., Vogt, P.K. Oncogene (2004)
- A novel src- and ras-suppressed protein kinase C substrate associated with cytoskeletal architecture. Lin, X., Tombler, E., Nelson, P.J., Ross, M., Gelman, I.H. J. Biol. Chem. (1996)
- Gene trap insertion reveals two open reading frames in the mouse SSeCKS gene: the form predominantly detected in the nervous system is suppressed by the insertion while the other, specific of the testis, remains expressed. Camus, A., Mesbah, K., Rallu, M., Babinet, C., Barra, J. Mech. Dev. (2001)
- Control of cytoskeletal architecture by the src-suppressed C kinase substrate, SSeCKS. Gelman, I.H., Lee, K., Tombler, E., Gordon, R., Lin, X. Cell Motil. Cytoskeleton (1998)
- Calmodulin and cyclin D anchoring sites on the Src-suppressed C kinase substrate, SSeCKS. Lin, X., Gelman, I.H. Biochem. Biophys. Res. Commun. (2002)
- Mitogen-induced, FAK-dependent tyrosine phosphorylation of the SSeCKS scaffolding protein. Xia, W., Gelman, I.H. Exp. Cell Res. (2002)
- Induction of Src-suppressed C kinase substrate (SSeCKS) in vascular endothelial cells by bacterial lipopolysaccharide. Kitamura, H., Okita, K., Fujikura, D., Mori, K., Iwanaga, T., Saito, M. J. Histochem. Cytochem. (2002)
- A role for SSeCKS, a major protein kinase C substrate with tumour suppressor activity, in cytoskeletal architecture, formation of migratory processes, and cell migration during embryogenesis. Gelman, I.H., Tombler, E., Vargas, J. Histochem. J. (2000)
- Reexpression of the major protein kinase C substrate, SSeCKS, suppresses v-src-induced morphological transformation and tumorigenesis. Lin, X., Gelman, I.H. Cancer Res. (1997)
- SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis. Liu, Y., Gao, L., Gelman, I.H. BMC Cancer (2006)
- The expression of src-suppressed C kinase substrate (SSeCKS) and uptake of exogenous particles in endothelial and reticular cells. Rung-ruangkijkrai, T., Fujikura, D., Kitamura, H., Saito, M., Iwanaga, T. Arch. Histol. Cytol. (2004)