Disease relevance of Abortion, Induced

• Furthermore, parvovirus B19 DNA was found in two (5%) of the miscarriages but not in any of the cases of induced abortion [1].
• Fetal death rate, corrected for induced abortions, was markedly higher when SLE first manifested during or immediately after the index gestation (five of 11, or 45%) than in pregnancies that began prior to clinical onset of SLE (16 of 140, or 11.4%) and in those occurring after onset of SLE (five of 38, or 13.1%) [2].
• Luteal-phase progesterone metabolite levels tended to be lower among women who were overweight, were less educated, were older at their first livebirth, or had an induced abortion [3].
• They ended in: 3 induced abortions indicated for severe morphological anomalies (n = 2) and for SLE relapse (n = 1), 3 spontaneous miscarriages, and 10 deliveries of healthy newborns [4].
• Parity, spontaneous or induced abortions and history of infertility were not associated with thyroid cancer risk [5].

High impact information on Abortion, Induced

• To identify these risks, we analyzed information from two separate sets of data collected by the Centers for Disease Control: that of the Joint Program for the Study of Abortion, a multicenter prospective study of nearly 165,000 legally induced abortions; and that of a national surveillance of abortion-related mortality [6].
• Cervical pre-dilation with misoprostol may be considered in all women having surgically induced abortions [7].
• Letter: Alpha-fetoprotein during mid-trimester induced abortion [8].
• Longer term inhalation, as in addicts, produces a syndrome similar to that due to B12 neuropathy, and long term exposure to low concentrations results in an increased abortion rate and neuropathy, particularly in dental personnel [9].
• Finally, GnRH analog suppression in PCOS permitted normalization of the follicular phase endocrine pattern, achievement of good ovulatory (76%) and pregnancy (28%) rates, and avoidance of multiple pregnancies; however, luteal phase steroid secretion was abnormal, and the abortion rate remained elevated (43%) [10].

Chemical compound and disease context of Abortion, Induced

• Midtrimester abortion induced by hyperosmolar urea and prostaglandin F2 alpha in patients with previous cesarean section: clinical course and potential for uterine rupture [11].
• CONCLUSIONS: Selective pelvic arterial embolization may be a successful treatment for hemorrhage associated with spontaneous and induced abortion [12].
• The reduced production of prostacyclin might be responsible for an increased abortion rate and a higher rate of intrauterine fetal death because of a decrease in placental perfusion and umbilical blood flow [13].
• Anencephaly was diagnosed, followed by prostaglandin induced abortion and fetotomy [14].
• Heparin reduces significantly the abortion rate in mice and recurrent spontaneous abortion (RSA) patients [15].

Biological context of Abortion, Induced

• Between 1972 and 1978, as legal abortion became more widely available nationally, abortion rates (abortions per 1,000 women) and ratios (abortions per 1,000 live births) increased for all American teenagers; from 1972 to 1975, the rates and ratios for teenagers for Black and other races increased faster than those for White teenagers [16].
• Coagulopathy with midtrimester induced abortion: association with hyperosmolar urea administration [17].
• The use of prostaglandin E1 analogue pessaries in patients having first trimester induced abortions [18].
• No relationship was found to progesterone, maternal age, parity, or previous abortion [19].
• A single intramuscular dose of methotrexate used without prostaglandins induced abortion in most women at gestational ages of less than 6 weeks [20].

Anatomical context of Abortion, Induced

• Prolactin and human placental lactogen changes in maternal serum and amniotic fluid in midtrimester induced abortions [21].
• Intravenous injection of small amounts of monospecific rabbit IgG against pregnancy-associated murine protein I (PAMP-I) induced abortion in mice where there was a histocompatibility difference between mother and fetuses [22].
• One-way mixed wife-husband lymphocyte culture (MLC) reaction as well as human lymphocyte antigen (HLA) typing were performed on 29 couples, most of whom were infertile because of recurrent spontaneous abortion, and compared with 35 fertile couples with no abortion history [23].
• STUDY SELECTION: We included all studies reported in English and published before March 31, 2001, which evaluated the efficacy of misoprostol alone for labor and delivery, evacuation of the uterus after pregnancy failure and induced abortion [24].
• OBJECTIVE: To determine the effect of the presence of Ureaplasma urealyticum in semen on IVF outcome (fertilization, pregnancy, and abortion rates) [25].

Associations of Abortion, Induced with chemical compounds

• LH-AS on day 9 induced abortion and a rapid, drastic and permanent fall in the progesterone level in all rats [26].
• This study suggests that one early abortion induced by mifepristone in nulliparous women has no adverse effects on the outcome of a subsequent pregnancy [27].
• Generally, women with a prior pregnancy or those with a later age at menarche had lower estrogen metabolite levels, whereas women with prior induced abortions had higher levels [3].
• Increased access to induced abortion following the 1973 U.S. Supreme Court decision appears to have been responsible for the decline [28].
• Sudden collapse and death of women obtaining abortions induced with prostaglandin F2alpha [29].

Gene context of Abortion, Induced

• RESULTS: The stress-triggered abortion rate was reduced by 68% when either TNF-alpha or IL-1 antagonists were injected [30].
• Anti-CD200 antibody raised the abortion rate to predicted levels, and infusion of a CD200 immunoadhesin reduced the abortion rate, as did an anti-MD-1 antibody [31].
• RESULTS: Stress and SP injection significantly increased the abortion rate and up-regulated decidual NGF and TrkA expression compared with the control [32].
• Mifepristone (Ru486) antagonizes monocyte chemotactic protein-3 down-regulation at early mouse pregnancy revealing immunomodulatory events in Ru486 induced abortion [33].
• Treatment by GM-CSF, IL-3, or anti-natural killer antiserum decreases both TNF levels and abortion rates [34].

Analytical, diagnostic and therapeutic context of Abortion, Induced

• In addition, women whose urine samples were positive for cocaine were more likely to have no prenatal care, previous induced abortions, to be human immunodeficiency virus-positive, and admitted previous use of cigarettes, alcohol, cocaine, and other drugs [35].
• Intramuscular injections of 15(S)-15-methyl prostaglandin F2alpha (15-Me-PGF2alpha) induced abortion in 38 patients who had failed to abort with other techniques, such as intra-amniotic instillation of saline or PGF2alpha and intravaginal insertion of prostaglandin-impragnated Silastic devices [36].
• Cervical softening by vaginal administration of a prostaglandin E1 analogue (ONO-802) was studied in a double-blind, placebo-controlled study using an objective measure of cervical resistance in 121 women undergoing first trimester induced abortion [37].
• The effect of meperidine analgesia on midtrimester abortions induced with intra-amniotic prostaglandin F2alpha [38].
• Statistically significant differences between the ICSI and IVF groups were noted for maternal age (31.3 +/- 4.4 vs. 33.4 +/- 4.8, respectively, P < 0.005) and clinical abortion rate (11% vs. 24%, respectively, P < 0.05) [39].

References