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MeSH Review

Anemia, Refractory

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Biological context of Anemia, Refractory


Anatomical context of Anemia, Refractory


Gene context of Anemia, Refractory


Analytical, diagnostic and therapeutic context of Anemia, Refractory


  1. Late-onset X-linked sideroblastic anemia. Missense mutations in the erythroid delta-aminolevulinate synthase (ALAS2) gene in two pyridoxine-responsive patients initially diagnosed with acquired refractory anemia and ringed sideroblasts. Cotter, P.D., May, A., Fitzsimons, E.J., Houston, T., Woodcock, B.E., al-Sabah, A.I., Wong, L., Bishop, D.F. J. Clin. Invest. (1995) [Pubmed]
  2. Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders. Pettenati, M.J., Le Beau, M.M., Lemons, R.S., Shima, E.A., Kawasaki, E.S., Larson, R.A., Sherr, C.J., Diaz, M.O., Rowley, J.D. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  3. Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts. Estey, E.H., Thall, P.F., Cortes, J.E., Giles, F.J., O'Brien, S., Pierce, S.A., Wang, X., Kantarjian, H.M., Beran, M. Blood (2001) [Pubmed]
  4. Clonal involvement of granulocytes and monocytes, but not of T and B lymphocytes and natural killer cells in patients with myelodysplasia: analysis by X-linked restriction fragment length polymorphisms and polymerase chain reaction of the phosphoglycerate kinase gene. van Kamp, H., Fibbe, W.E., Jansen, R.P., van der Keur, M., de Graaff, E., Willemze, R., Landegent, J.E. Blood (1992) [Pubmed]
  5. Long-term follow-up in patients with aplastic anemia. A study of 137 androgen-treated patients surviving more than two years. Joint Group for the Study of Aplastic and Refractory Anemias. Najean, Y. Am. J. Med. (1981) [Pubmed]
  6. Bone marrow curettage in myelodysplastic disorders. A stimulus for regeneration in disturbed hematopoiesis. Matzner, Y., Polliack, A. JAMA (1981) [Pubmed]
  7. Treatment of anemia in inflammatory bowel disease with recombinant human erythropoietin: results in three patients. Horina, J.H., Petritsch, W., Schmid, C.R., Reicht, G., Wenzl, H., Silly, H., Krejs, G.J. Gastroenterology (1993) [Pubmed]
  8. Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis. Mihara, K., Chowdhury, M., Nakaju, N., Hidani, S., Ihara, A., Hyodo, H., Yasunaga, S., Takihara, Y., Kimura, A. Blood (2006) [Pubmed]
  9. Antithymocyte globulin has limited efficacy and substantial toxicity in unselected anemic patients with myelodysplastic syndrome. Steensma, D.P., Dispenzieri, A., Moore, S.B., Schroeder, G., Tefferi, A. Blood (2003) [Pubmed]
  10. Response to pyridoxine hydrochloride in refractory anemia due to myelofibrosis. Rojer, R.A., Mulder, N.H., Nieweg, H.O. Am. J. Med. (1978) [Pubmed]
  11. Low dose Ara-C for patients with myelodysplastic syndromes. Powell, B.L., Capizzi, R.L., Jackson, D.V., Richards, F., Muss, H.B., Lyerly, E.S., Rosenbaum, D.L., Connelly, R.A., Buss, D.H., Bearden, J.D. Leukemia (1988) [Pubmed]
  12. Animal models of fulminant hepatic failure: a critical evaluation. Newsome, P.N., Plevris, J.N., Nelson, L.J., Hayes, P.C. Liver Transpl. (2000) [Pubmed]
  13. Treatment of myelodysplastic syndromes with orally administered 1-beta-D-arabinofuranosylcytosine-5'-stearylphosphate. Ohno, R., Tatsumi, N., Hirano, M., Imai, K., Mizoguchi, H., Nakamura, T., Kosaka, M., Takatsuki, K., Yamaya, T., Toyama, K. Oncology (1991) [Pubmed]
  14. Endogenous serum thrombopoietin concentrations in patients with myelodysplastic syndromes. Zwierzina, H., Rollinger-Holzinger, I., Nuessler, V., Herold, M., Meng, Y.G. Leukemia (1998) [Pubmed]
  15. Studies on red-cell aplasia: IX. Ferrokinetics during remission of the disease. Wibulyachainunt, S., Price, R., Brill, A.B., Krantz, S.B. Am. J. Hematol. (1978) [Pubmed]
  16. Characterization of clonogenic cells in refractory anemia with excess of blasts (RAEB-CFU): response to recombinant hematopoietic growth factors and maturation phenotypes. Schouten, H.C., Delwel, R., Bot, F.J., Hagemeijer, A., Touw, I.P., Löwenberg, B. Leuk. Res. (1989) [Pubmed]
  17. Impact of growth factors in the regulation of apoptosis in low-risk myelodysplastic syndromes. Tehranchi, R. Med. Oncol. (2006) [Pubmed]
  18. Myelodysplastic syndrome with monosomy 7 after immunosuppressive therapy in Behçet's disease. Bangerter, M., Griesshammer, M., v Tirpitz, C., Krauter, J., Heil, G., Hafner, M., Kern, W., Heiss, M., Kern, P. Scand. J. Rheumatol. (1999) [Pubmed]
  19. Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Cazzola, M., Invernizzi, R., Bergamaschi, G., Levi, S., Corsi, B., Travaglino, E., Rolandi, V., Biasiotto, G., Drysdale, J., Arosio, P. Blood (2003) [Pubmed]
  20. Spontaneous intramedullary apoptosis is present in disorders other than myelodysplasia. Irvine, A.E., Magill, M.K., Somerville, L.E., McMullin, M.F. Exp. Hematol. (1998) [Pubmed]
  21. Treatment of two patients with Herlitz junctional epidermolysis bullosa with artificial skin bioequivalents. Jiang, Q.J., Izakovic, J., Zenker, M., Fartasch, M., Meneguzzi, G., Rascher, W., Schneider, H. J. Pediatr. (2002) [Pubmed]
  22. Trilineage recovery by combination therapy with recombinant human granulocyte colony-stimulating factor and erythropoietin in patients with aplastic anemia and refractory anemia. Bessho, M., Jinnai, I., Hirashima, K., Saito, M., Murohashi, I., Ino, H., Tsuji, M., Fukuda, M., Maruyama, M., Kusumoto, S. Stem Cells (1994) [Pubmed]
  23. Immunosuppressive therapy for patients with refractory anemia. Asano, Y., Maeda, M., Uchida, N., Yokoyama, T., Osaki, K., Shimoda, K., Gondo, H., Okamura, T., Okamura, S., Niho, Y. Ann. Hematol. (2001) [Pubmed]
  24. Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia. López-Karpovitch, X., Barrales-Benítez, O., Flores, M., Piedras, J. Cytokine (2002) [Pubmed]
  25. Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. Sawanobori, M., Yamaguchi, S., Hasegawa, M., Inoue, M., Suzuki, K., Kamiyama, R., Hirokawa, K., Kitagawa, M. Leuk. Res. (2003) [Pubmed]
  26. Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5. Bahou, W.F., Nierman, W.C., Durkin, A.S., Potter, C.L., Demetrick, D.J. Blood (1993) [Pubmed]
  27. Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts. La Starza, R., Gorello, P., Rosati, R., Riezzo, A., Veronese, A., Ferrazzi, E., Martelli, M.F., Negrini, M., Mecucci, C. Genes Chromosomes Cancer (2004) [Pubmed]
  28. Analysis of the erythropoietin receptor gene in patients with myeloproliferative and myelodysplastic syndromes. Mittelman, M., Gardyn, J., Carmel, M., Malovani, H., Barak, Y., Nir, U. Leuk. Res. (1996) [Pubmed]
  29. Engraftment of HLA-matched sibling hematopoietic stem cells after immunosuppressive conditioning regimen in patients with hematologic neoplasias. Carella, A.M., Lerma, E., Dejana, A., Corsetti, M.T., Celesti, L., Bruni, R., Benvenuto, F., Figari, O., Parodi, C., Carlier, P., Florio, G., Lercari, G., Valbonesi, M., Casarino, L., De Stefano, F., Geniram, A., Venturino, M., Tedeschi, L., Palmieri, G., Piaggio, G., Podestà, M., Frassoni, F., Van Lint, M.T., Marmont, A.M., Bacigalupo, A. Haematologica (1998) [Pubmed]
  30. Autologous hemopoietic reconstitution after fetal liver infusion in patients with bone marrow failure: consequence or coincidence? Sierra, J., Badell, I., Grañena, A., García, J., Marín, P., Valls, A., Carreras, E., Torras, A., Rovira, M., Pujol, E. Bone Marrow Transplant. (1992) [Pubmed]
  31. Radiation-free regimens result in similar outcomes of allogeneic hematopoietic progenitor cell transplantation in patients aged >or=50 years compared to younger adults with low-risk disease. Farag, S.S., Elder, P.J., Marcucci, G., Penza, S., Mrozek, E., Molina, A., Lin, T., Avalos, B.R., Copelan, E. Bone Marrow Transplant. (2003) [Pubmed]
  32. Decreased amount of mpl and reduced expression of glycoprotein IIb/IIIa and glycoprotein Ib on platelets from patients with refractory anemia: analysis by a non-isotopic quantitative ligand binding assay and immunofluorescence. Izumi, M., Takeshita, A., Shinjo, K., Naito, K., Matsui, H., Shibata, K., Ohnishi, K., Kanno, T., Ohno, R. Eur. J. Haematol. (2001) [Pubmed]
  33. Lichenoid nail changes as sole external manifestation of graft vs. host disease. Palencia, S.I., Rodríguez-Peralto, J.L., Castaño, E., Vanaclocha, F., Iglesias, L. International journal of dermatology. (2002) [Pubmed]
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