The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Abortion, Legal

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Abortion, Legal


High impact information on Abortion, Legal

  • Fifteen of these women were restudied with TRH stimulation 4--6 weeks after legal abortion, and the PRL responses to TRH were normal [6].
  • The environmental influence of various drugs on the epoxide hydrolase with styrene oxide (EHSO) or benzo(a)pyrene-4,5-oxide (EHBPox) as substrate and the aryl hydrocarbon hydroxylase (AHH) activity was studied in monolayer cultures of human fetal hepatocytes (HFH) obtained at legal abortions [7].
  • Cytotrophoblasts were isolated from legal abortions, immunopurified with anti-CD45, separated according to their expression of histocompatibility-linked antigen (HLA)-G, alpha 6 or alpha 5 integrin subunits and cultured for 5 days on plastic or agarose [8].
  • OBJECTIVE: To investigate the use of oral mifepristone (RU486; Roussel-Uclaf, Paris, France) associated with IM injection of sulprostone (Schering, Lys-Lez-Lannoy, France) for the induction of legal abortion (7 weeks of amenorrhea in France) [9].
  • A total of 363 women undergoing legal abortion at < 63 days of amenorrhoea were allocated by a patient-centered, partially randomized study design to undergo medical abortion (using mifepristone 600 mg followed 48 h later by gemeprost 1 mg vaginal pessary) or vacuum aspiration (performed under general anaesthesia) [10].

Biological context of Abortion, Legal


Associations of Abortion, Legal with chemical compounds

  • Because many associations were examined without previous hypotheses, and because the data were inadequate to show an elevated risk for clotrimazole when comparing spontaneous with legal abortion exposures, these findings are considered to be a signal for further studies rather than definitive in themselves [15].
  • Twenty-seven healthy females referred for legal abortion between the sixth and ninth week of pregnancy were treated for 1 week with either bromocriptine, metoclopramide or placebo [16].
  • When women were retested with TRH before and during bromocriptine after legal abortion, bromocriptine did not change the basal levels of TSH, T3 and T4 or the TSH response to TRH [17].
  • The study included 71 women requesting legal abortion in the 15th to 23rd week of pregnancy who were treated with repeated vaginal applications of 9-methylene PGE2 in a hydrophilic gel (5 mg every 4th hour) following pretreatment with 200 mg of RU 486 and/or intracervical administration of 0.5 mg of PGE2 gel [18].
  • Injections of ACTH and HCG into the fetus during midpregnancy legal abortion performed by intraamniotic instillation of prostaglandin. Influence on maternal plasma oestrogens and testosterone [19].

Gene context of Abortion, Legal

  • After placental removal at cesarean section in late pregnancy there was a rapid fall in serum GH concentration, whereas levels were unaffected after legal abortion in the first trimester [20].
  • The embryos were collected after legal abortions, embedded in paraffin, serially cut in transversal direction and treated with S35 labeled probe for PAX2 [21].
  • This patient had experienced legal abortion 3 months ago, and the presence of PSBG and hCG in her serum may represent prolonged trophoblastic activity after pregnancy [22].
  • Attempts to demonstrate CMV IgM activity as a marker of active infection in sera from early pregnancy (period of legal abortion) were successful in only half of the 10 cases with infant sequelae or death [2].
  • A 26-year-old woman, treated with phenytoin for 10 years because of epilepsy, had Norplant subdermal implants inserted after a legal abortion [23].

Analytical, diagnostic and therapeutic context of Abortion, Legal


  1. The morbidity and mortality of pregnancy: still risky business. Grimes, D.A. Am. J. Obstet. Gynecol. (1994) [Pubmed]
  2. Congenital cytomegalovirus infection: on the relation between type and time of maternal infection and infant's symptoms. Ahlfors, K., Forsgren, M., Ivarsson, S.A., Harris, S., Svanberg, L. Scand. J. Infect. Dis. (1983) [Pubmed]
  3. Atrial natriuretic peptide in the ventricles of patients with dilated cardiomyopathy and human foetuses. Jougasaki, M., Yasue, H., Okumura, K., Mukoyama, M., Saito, Y., Nakao, K., Takahashi, K. Histochem. J. (1989) [Pubmed]
  4. Serum levels of free fatty acids in the first trimester of pregnancy: effect of acetylsalicylic acid. Haataja, M., Grönroos, M., Honkonen, E., Paul, R., Nieminen, A.L., Anttila, M. Prostaglandins, leukotrienes, and medicine. (1982) [Pubmed]
  5. A clinical double-blind study on the effect of prophylactically administered single dose tinidazole on the occurrence of endometritis after first trimester legal abortion. Weström, L., Svensson, L., Wölner-Hanssen, P., Mårdh, P.A. Scandinavian journal of infectious diseases. Supplementum. (1981) [Pubmed]
  6. Does bromocriptine block thyrotropin-releasing hormone-induced prolactin release during pregnancy? Ylikorkala, O., Kivinen, S., Rönnberg, L., Viinikka, L. J. Clin. Endocrinol. Metab. (1980) [Pubmed]
  7. Human fetal liver cultures: basal activities and inducibility of epoxide hydrolases and aryl hydrocarbon hydroxylase. Peng, D.R., Pacifici, G.M., Rane, A. Biochem. Pharmacol. (1984) [Pubmed]
  8. Gelatinase and oncofetal fibronectin secretion is dependent on integrin expression on human cytotrophoblasts. Bischof, P., Haenggeli, L., Campana, A. Hum. Reprod. (1995) [Pubmed]
  9. Analysis of 369 abortions conducted by mifepristone (RU486) associated with sulprostone in a French family planning center. Thonneau, P., Fougeyrollas, B., Spira, A. Fertil. Steril. (1994) [Pubmed]
  10. A comparison of medical abortion (using mifepristone and gemeprost) with surgical vacuum aspiration: efficacy and early medical sequelae. Henshaw, R.C., Naji, S.A., Russell, I.T., Templeton, A.A. Hum. Reprod. (1994) [Pubmed]
  11. Second trimester pregnancy termination using extra-amniotic ethacridine lactate. Bhathena, R.K., Sheriar, N.K., Walvekar, V.R., Guillebaud, J. British journal of obstetrics and gynaecology. (1990) [Pubmed]
  12. Immunohistochemical demonstration of luteinizing hormone-releasing factor-like material in human syncytiotrophoblast and trophoblastic tumours. Seppälä, M., Wahlström, T., Lehtovirta, P., Lee, J.N., Leppälouto, J. Clin. Endocrinol. (Oxf) (1980) [Pubmed]
  13. Vaginal application of a chemotherapeutic agent before legal abortion. A way of reducing infectious complication? Meirik, O., Nilsson, S., Nygren, K.G. Acta obstetricia et gynecologica Scandinavica. (1981) [Pubmed]
  14. Cervical dilatation before first trimester elective abortion: a comparison between laminaria and a newly developed hydrogel tent, the A rod. Molin, A., Brundin, J. Gynecol. Obstet. Invest. (1992) [Pubmed]
  15. Pregnancy outcomes after first-trimester vaginitis drug therapy. Rosa, F.W., Baum, C., Shaw, M. Obstetrics and gynecology. (1987) [Pubmed]
  16. Ovarian and placental hormones during prolactin suppression and stimulation in early human pregnancy. Andersen, A.N., Hertz, J., Kjer, J.J., Eskildsen, P.C., Larsen, P.S., Svenstrup, B., Nielsen, J., Arends, J. Clin. Endocrinol. (Oxf) (1980) [Pubmed]
  17. Bromocriptine suppresses the thyrotrophin response to thyrotrophin releasing hormone during human pregnancy. Ylikorkala, O., Kivinen, S., Rönnberg, L., Viinikka, L. Clin. Endocrinol. (Oxf) (1980) [Pubmed]
  18. The use of antiprogestin (RU 486) for termination of second trimester pregnancy. Gottlieb, C., Bygdeman, M. Acta obstetricia et gynecologica Scandinavica. (1991) [Pubmed]
  19. Injections of ACTH and HCG into the fetus during midpregnancy legal abortion performed by intraamniotic instillation of prostaglandin. Influence on maternal plasma oestrogens and testosterone. Strecker, J.R., Lauritzen, C., Dahlén, H., Jonatha, W., Gossler, W., Tettenborn, U. Horm. Metab. Res. (1977) [Pubmed]
  20. Growth hormone in human pregnancy. Maternal 24-hour serum profiles and experimental effects of continuous GH secretion. Eriksson, L. Acta obstetricia et gynecologica Scandinavica. Supplement. (1989) [Pubmed]
  21. Expression of PAX2 gene during human development. Terzić, J., Muller, C., Gajović, S., Saraga-Babić, M. Int. J. Dev. Biol. (1998) [Pubmed]
  22. Pregnancy-specific beta-1 glycoprotein in ectopic pregnancy. Seppälä, M., Venesmaa, P., Rutanen, E.M. Am. J. Obstet. Gynecol. (1980) [Pubmed]
  23. Enhanced metabolism of levonorgestrel during phenytoin treatment in a woman with Norplant implants. Odlind, V., Olsson, S.E. Contraception. (1986) [Pubmed]
  24. Transfer of nitrazepam across the human placenta. Kangas, L., Kanto, J., Erkkola, R. Eur. J. Clin. Pharmacol. (1977) [Pubmed]
  25. Clinical experiences with a new gel for intracervical application of prostaglandin E2 before therapeutic abortion or induction of term labor. Ulmsten, U., Wingerup, L. Prostaglandins (1980) [Pubmed]
  26. Transfer of free and conjugated oxazepam across the human placenta. Kangas, L., Erkkola, R., Kanto, J., Eronen, M. Eur. J. Clin. Pharmacol. (1980) [Pubmed]
  27. A longitudinal study of birth control and pregnancy outcome among women in a Swedish population. Larsson, G., Blohm, F., Sundell, G., Andersch, B., Milsom, I. Contraception. (1997) [Pubmed]
WikiGenes - Universities