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MeSH Review

Wounds, Stab

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Disease relevance of Wounds, Stab


Psychiatry related information on Wounds, Stab


High impact information on Wounds, Stab

  • To examine the function of Olig2 in brain lesion, we injected retroviral vectors containing a dominant negative form of Olig2 into the lesioned cortex 2 days after a stab wound [1].
  • At brain stab wounds, microglia progressively accumulated over several days and formed aggregates that frequently showed Cx43 immunoreactivity at interfaces between cells [7].
  • Rabbit fibroblasts infected with a retroviral vector containing the human IL-1ra gene were implanted into the wound cavity immediately following a cortical stab wound or 6 hours after a weight drop-induced trauma [8].
  • We studied 324 patients admitted to Harlem Hospital Center from July 1981 to June 1986 with stab wounds of the thoracoabdominal region (area limited by a coronal circle through the fifth interspaces anteriorly and seventh interspaces posteriorly from above to a subcostal circle 5 cm caudad to the costal margins and 12th ribs from below) [9].
  • Additional rats were examined after a stab wound injury to assess the expression of two of these markers, GFAP and nestin, in reactive astrocytes [10].

Chemical compound and disease context of Wounds, Stab


Biological context of Wounds, Stab


Anatomical context of Wounds, Stab


Gene context of Wounds, Stab


Analytical, diagnostic and therapeutic context of Wounds, Stab

  • The extravasation of albumin around small cerebral stab wounds in the rat frontal cortex was studied by fluorescence microscopy after i.v. injection of Evans blue-labeled albumin and by quantitative immunoelectrophoresis after i.v. injection of bovine albumin, in both nonintoxicated and ethanol-intoxicated rats [3].
  • Brains of rats that had received needle stab wounds were examined sequentially for 72 h by immunohistochemistry using antibodies to beta-amyloid precursor protein (APP) [27].
  • Cortical stab wound injury resulted in HO-1 induction as determined by Western blot analysis [23].
  • Using the antibody and GIF cDNA probe, we investigated changes of GIF and GIF mRNA by Western and Northern blotting techniques in rat brains after stab wounds [28].
  • Under arthroscopic view, a slotted cannula was inserted into the digital sheath through a stab wound proximal to the annular ligament and advanced through the fetlock canal superficial to the flexor tendons with the slot oriented toward the fibers of the annular ligament [29].


  1. Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair. Buffo, A., Vosko, M.R., Ertürk, D., Hamann, G.F., Jucker, M., Rowitch, D., Götz, M. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  2. Regulation of gene expression in response to brain injury: enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain. Hiraiwa, M., Liu, J., Lu, A.G., Wang, C.Y., Misasi, R., Yamauchi, T., Hozumi, I., Inuzuka, T., O'Brien, J.S. J. Neurotrauma (2003) [Pubmed]
  3. Chlorpromazine treatment of blood-brain barrier dysfunction. A quantitative and fluorescence microscopical study on small cerebral stab wounds in the rat. Rosengren, L.E., Persson, L.I. Acta Neuropathol. (1979) [Pubmed]
  4. GFAP mRNA levels following stab wounds in rat brain. Hozumi, I., Aquino, D.A., Norton, W.T. Brain Res. (1990) [Pubmed]
  5. TGF-alpha overexpression induces astrocytic hypertrophy after cortical stab wound injury. Isono, M., Goda, M., Kobayashi, H., Wu, J.L. Neurol. Res. (2003) [Pubmed]
  6. Administration of prosaposin ameliorates spatial learning disturbance and reduces cavity formation following stab wounds in rat brain. Hozumi, I., Hiraiwa, M., Inuzuka, T., Yoneoka, Y., Akiyama, K., Tanaka, R., Kikugawa, K., Nakano, R., Tsuji, S., O'Brien, J.S. Neurosci. Lett. (1999) [Pubmed]
  7. Microglia at brain stab wounds express connexin 43 and in vitro form functional gap junctions after treatment with interferon-gamma and tumor necrosis factor-alpha. Eugenín, E.A., Eckardt, D., Theis, M., Willecke, K., Bennett, M.V., Saez, J.C. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  8. Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain. DeKosky, S.T., Styren, S.D., O'Malley, M.E., Goss, J.R., Kochanek, P., Marion, D., Evans, C.H., Robbins, P.D. Ann. Neurol. (1996) [Pubmed]
  9. Management of stab wounds to the thoracoabdominal region. A clinical approach. Mariadason, J.G., Parsa, M.H., Ayuyao, A., Freeman, H.P. Ann. Surg. (1988) [Pubmed]
  10. Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis. Jang, T., Litofsky, N.S., Smith, T.W., Ross, A.H., Recht, L.D. Neurobiol. Dis. (2004) [Pubmed]
  11. Amoeboid and ramified microglia: their interrelationship and response to brain injury. Leong, S.K., Ling, E.A. Glia (1992) [Pubmed]
  12. Immunohistochemical markers for neurons and astrocytes show pan-necrosis following infusion of high-dose NMDA into rat cortex. Ingvar, M., Schmidt-Kastner, R., Meller, D. Exp. Neurol. (1994) [Pubmed]
  13. Astrocyte cell lineage. V. Similarity of astrocytes that form in the presence of dBcAMP in cultures to reactive astrocytes in vivo. Fedoroff, S., McAuley, W.A., Houle, J.D., Devon, R.M. J. Neurosci. Res. (1984) [Pubmed]
  14. Expression of growth inhibitory factor (GIF) in normal and injured rat brains. Anezaki, T., Ishiguro, H., Hozumi, I., Inuzuka, T., Hiraiwa, M., Kobayashi, H., Yuguchi, T., Wanaka, A., Uda, Y., Miyatake, T. Neurochem. Int. (1995) [Pubmed]
  15. Extravasation, spread and cellular uptake of Evans blue-labelled albumin around a reproducible small stab-wound in the rat brain. Persson, L., Hansson, H.A., Sourander, P. Acta Neuropathol. (1976) [Pubmed]
  16. Voltage-dependent potassium currents in hypertrophied rat astrocytes after a cortical stab wound. Anderová, M., Antonova, T., Petrík, D., Neprasová, H., Chvátal, A., Syková, E. Glia (2004) [Pubmed]
  17. The effect of acute ethanol intoxication and chronic ethanol consumption on vascular permeability around cerebral stab wounds in mice. Heinicke, E.A. Acta Neuropathol. (1982) [Pubmed]
  18. Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat. Gordon, M.N., Schreier, W.A., Ou, X., Holcomb, L.A., Morgan, D.G. J. Comp. Neurol. (1997) [Pubmed]
  19. Chemokine expression in rat stab wound brain injury. Ghirnikar, R.S., Lee, Y.L., He, T.R., Eng, L.F. J. Neurosci. Res. (1996) [Pubmed]
  20. Constant postoperative monitoring of cardiac output after correction of congenital heart defects. Keagy, B.A., Wilcox, B.R., Lucas, C.L., Hsiao, H.S., Henry, G.W., Baudino, M., Bornzin, G. J. Thorac. Cardiovasc. Surg. (1987) [Pubmed]
  21. Sniffing-associated deaths in Denmark. Kringsholm, B. Forensic Sci. Int. (1980) [Pubmed]
  22. Differential cellular accumulation of connective tissue growth factor defines a subset of reactive astrocytes, invading fibroblasts, and endothelial cells following central nervous system injury in rats and humans. Schwab, J.M., Beschorner, R., Nguyen, T.D., Meyermann, R., Schluesener, H.J. J. Neurotrauma (2001) [Pubmed]
  23. Transient induction of heme oxygenase after cortical stab wound injury. Dwyer, B.E., Nishimura, R.N., Lu, S.Y., Alcaraz, A. Brain Res. Mol. Brain Res. (1996) [Pubmed]
  24. Roles of urokinase type plasminogen activator in a brain stab wound. Kataoka, K., Asai, T., Taneda, M., Ueshima, S., Matsuo, O., Kuroda, R., Kawabata, A., Carmeliet, P. Brain Res. (2000) [Pubmed]
  25. Regulation of the heparan sulfate proteoglycan, perlecan, by injury and interleukin-1alpha. García de Yébenes, E., Ho, A., Damani, T., Fillit, H., Blum, M. J. Neurochem. (1999) [Pubmed]
  26. Identification of CD40 ligand in Alzheimer's disease and in animal models of Alzheimer's disease and brain injury. Calingasan, N.Y., Erdely, H.A., Altar, C.A. Neurobiol. Aging (2002) [Pubmed]
  27. Rapid appearance of beta-amyloid precursor protein immunoreactivity in damaged axons and reactive glial cells in rat brain following needle stab injury. Otsuka, N., Tomonaga, M., Ikeda, K. Brain Res. (1991) [Pubmed]
  28. Changes of growth inhibitory factor after stab wounds in rat brain. Hozumi, I., Inuzuka, T., Hiraiwa, M., Uchida, Y., Anezaki, T., Ishiguro, H., Kobayashi, H., Uda, Y., Miyatake, T., Tsuji, S. Brain Res. (1995) [Pubmed]
  29. Endoscopically assisted annular ligament release in horses. Nixon, A.J., Sams, A.E., Ducharme, N.G. Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons. (1993) [Pubmed]
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