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MeSH Review


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Disease relevance of Neostriatum


Psychiatry related information on Neostriatum


High impact information on Neostriatum


Chemical compound and disease context of Neostriatum


Biological context of Neostriatum


Anatomical context of Neostriatum


Associations of Neostriatum with chemical compounds

  • Lane et al. have been able to circumvent this problem, at least in part, by the application of differential pulse voltametry (DPV) to a surface-modified platinum electrode, obtaining distinct oxidation current peaks in recordings from the rat neostriatum which are attributed to AA and to dopamine (DA), respectively, but which are also unstable [13].
  • Moreover, pharmacological investigations suggest that the catecholamine peak measured in vivo in the rat neostriatum should be attributed to 3, 4-dihydroxyphenylacetic acid (DOPAC), suggesting that our technique may be a useful means of following dopaminergic activity in vivo [13].
  • Opposing roles for D-1 and D-2 dopamine receptors in efflux of cyclic AMP from rat neostriatum [31].
  • Angiotensin injected into the neostriatum after learning disrupts retention performance [26].
  • Hyman and colleagues now report the characterization of ania-6, a novel cyclin that associates with RNA polymerase II and is induced by dopamine or cocaine in the neostriatum [32].

Gene context of Neostriatum

  • Neuronal CIP4 immunoreactivity increased with neuropathological severity in the neostriatum of HD patients and partially colocalized to ubiquitin-positive aggregates [33].
  • In the neostriatum of HD, NR1, NR2B and GLT1mRNA decreased in correlation to disease severity [34].
  • NR1/NR2B and GLT1mRNA expression was not homogeneously lower in the neostriatum; zones with stronger hybridization signals corresponded to the matrix compartment and consisted of a larger number of cells with high mRNA levels [34].
  • In the present study we have evaluated changes in nerve growth factor (NGF), brain-derived neurotrophic factor, and neurotrophin 3 (NT-3) mRNA expression induced by different glutamate receptor agonists injected into the neostriatum [35].
  • Similar to reports in other songbird species, we detected AR mRNA-containing cells in several song control nuclei, including the high vocal center (HVc), the medial and lateral portions of the magnocellular nucleus of the anterior neostriatum, and the robust nucleus of the archistriatum [36].

Analytical, diagnostic and therapeutic context of Neostriatum


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  9. Extracellular adenosine levels in neostriatum and hippocampus during rest and activity periods of rats. Huston, J.P., Haas, H.L., Boix, F., Pfister, M., Decking, U., Schrader, J., Schwarting, R.K. Neuroscience (1996) [Pubmed]
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  14. Enkephalin and opiate narcotics increase cyclic GMP accumulation in slices of rat neostriatum. Minneman, K.P., Iversen, I.L. Nature (1976) [Pubmed]
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  22. Somatostatin is increased in the basal ganglia in Huntington disease. Aronin, N., Cooper, P.E., Lorenz, L.J., Bird, E.D., Sagar, S.M., Leeman, S.E., Martin, J.B. Ann. Neurol. (1983) [Pubmed]
  23. Involvement of GABA systems in feedback regulation of glutamate-and GABA-mediated synaptic potentials in rat neostriatum. Calabresi, P., Mercuri, N.B., De Murtas, M., Bernardi, G. J. Physiol. (Lond.) (1991) [Pubmed]
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  26. Angiotensin injected into the neostriatum after learning disrupts retention performance. Morgan, J.M., Routtenberg, A. Science (1977) [Pubmed]
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  32. A novel cyclin provides a link between dopamine and RNA processing. Nairn, A.C., Greengard, P. Neuron (2001) [Pubmed]
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