The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Abelson murine leukemia virus

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Abelson murine leukemia virus


High impact information on Abelson murine leukemia virus

  • In the present study, plasmid was constructed in which human MRP-1/CD9 cDNA is expressed under the control of the Abelson murine leukemia virus promoter sequence [6].
  • To further analyze the VDJ recombination defect in lymphoid pre-B cells from mice with severe combined immune deficiency (scid mice), we have assayed the ability of Abelson murine leukemia virus (A-MuLV) transformed pre-B cells from scid mice to rearrange a recombination substrate in which inverted VH to DJH joins activate a selectable (gpt) gene [7].
  • The two Abelson murine leukemia virus (A-MuLV)-transformed cell lines, BM18-4 and ABC-1, undergo immunoglobulin L-chain gene recombination during passage in tissue culture [8].
  • Comparison of the tryptic peptides of p80 with those of the p120 gag-fusion protein of Abelson murine leukemia virus demonstrated that p80 and p120 did not share tryptic peptides [9].
  • Because Tp53 mutations are a common feature of the multistep pre-B cell transformation process mediated by Abelson murine leukemia virus (Ab-MLV), we examined the possibility that proteins encoded by the Ink4a/Arf locus also play a role in Abelson virus transformation [10].

Chemical compound and disease context of Abelson murine leukemia virus


Biological context of Abelson murine leukemia virus


Anatomical context of Abelson murine leukemia virus


Gene context of Abelson murine leukemia virus


Analytical, diagnostic and therapeutic context of Abelson murine leukemia virus


  1. Origin and functional properties of the major gene product of the Snyder-Theilen strain of feline sarcoma virus. Barbacid, M., Beemon, K., Devare, S.G. Proc. Natl. Acad. Sci. U.S.A. (1980) [Pubmed]
  2. Rearrangement and amplification of c-abl sequences in the human chronic myelogenous leukemia cell line K-562. Collins, S.J., Groudine, M.T. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  3. Addition of constitutive c-myc expression to Abelson murine leukemia virus changes the phenotype of the cells transformed by the virus from pre-B-cell lymphomas to plasmacytomas. Weissinger, E.M., Mischak, H., Goodnight, J., Davidson, W.F., Mushinski, J.F. Mol. Cell. Biol. (1993) [Pubmed]
  4. Induction by some protein kinase inhibitors of differentiation of a mouse megakaryoblastic cell line established by coinfection with Abelson murine leukemia virus and recombinant SV40 retrovirus. Honma, Y., Okabe-Kado, J., Kasukabe, T., Hozumi, M., Kajigaya, S., Suda, T., Miura, Y. Cancer Res. (1991) [Pubmed]
  5. Transforming pathways activated by the v-Abl tyrosine kinase. Shore, S.K., Tantravahi, R.V., Reddy, E.P. Oncogene (2002) [Pubmed]
  6. Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA. Ikeyama, S., Koyama, M., Yamaoko, M., Sasada, R., Miyake, M. J. Exp. Med. (1993) [Pubmed]
  7. Normal recombination substrate VH to DJH rearrangements in pre-B cell lines from scid mice. Ferrier, P., Covey, L.R., Li, S.C., Suh, H., Malynn, B.A., Blackwell, T.K., Morrow, M.A., Alt, F.W. J. Exp. Med. (1990) [Pubmed]
  8. Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines. Persiani, D.M., Durdik, J., Selsing, E. J. Exp. Med. (1987) [Pubmed]
  9. P80: a tumor-related protein found in many lymphomas of mice. Grunwald, D.J., Miller, K., Risser, R. J. Exp. Med. (1982) [Pubmed]
  10. p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation. Radfar, A., Unnikrishnan, I., Lee, H.W., DePinho, R.A., Rosenberg, N. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  11. Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients. Konopka, J.B., Clark, S., McLaughlin, J., Nitta, M., Kato, Y., Strife, A., Clarkson, B., Witte, O.N. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  12. Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesis. Nelson, K.J., Kelley, D.E., Perry, R.P. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  13. In vivo association of v-Abl with Shc mediated by a non-phosphotyrosine-dependent SH2 interaction. Raffel, G.D., Parmar, K., Rosenberg, N. J. Biol. Chem. (1996) [Pubmed]
  14. The hemopoietic progenitor 32DCl3(G) cells synthesize C3 molecules and acquire C3b acceptor sites upon differentiation or neoplastic transformation. Di Renzo, L., Zicari, A., Longo, A., Realacci, M., Naso, G., Pontieri, G., Lipari, M. J. Immunol. (1993) [Pubmed]
  15. Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6. Erikson, E., Maller, J.L. J. Biol. Chem. (1986) [Pubmed]
  16. Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia. Westbrook, C.A., Rubin, C.M., Le Beau, M.M., Kaminer, L.S., Smith, S.D., Rowley, J.D., Diaz, M.O. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  17. Cells arrested in G1 by the v-Abl tyrosine kinase do not express cyclin A despite the hyperphosphorylation of RB. Chen, Y., Knudsen, E.S., Wang, J.Y. J. Biol. Chem. (1996) [Pubmed]
  18. Rac is required for v-Abl tyrosine kinase to activate mitogenesis. Renshaw, M.W., Lea-Chou, E., Wang, J.Y. Curr. Biol. (1996) [Pubmed]
  19. Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus. Latt, S.A., Goff, S.P., Tabin, C.J., Paskind, M., Wang, J.Y., Baltimore, D. J. Virol. (1983) [Pubmed]
  20. STI-571: an anticancer protein-tyrosine kinase inhibitor. Roskoski, R. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  21. Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein. Daley, G.Q., Baltimore, D. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  22. Identification of a novel bone marrow-derived B-cell progenitor population that coexpresses B220 and Thy-1 and is highly enriched for Abelson leukemia virus targets. Tidmarsh, G.F., Heimfeld, S., Whitlock, C.A., Weissman, I.L., Müller-Sieburg, C.E. Mol. Cell. Biol. (1996) [Pubmed]
  23. Some lymphoid cell lines transformed by Abelson murine leukemia virus lack a major 36,000-dalton tyrosine protein kinase substrate. Sefton, B.M., Hunter, T., Cooper, J.A. Mol. Cell. Biol. (1983) [Pubmed]
  24. Effect of Abelson murine leukemia virus on granulocytic differentiation and interleukin-3 dependence of a murine progenitor cell line. Rovera, G., Valtieri, M., Mavilio, F., Reddy, E.P. Oncogene (1987) [Pubmed]
  25. Early arrest of B cell development in nude, X-linked immune-deficient mice. Karagogeos, D., Rosenberg, N., Wortis, H.H. Eur. J. Immunol. (1986) [Pubmed]
  26. NF-kappaB1 can inhibit v-Abl-induced lymphoid transformation by functioning as a negative regulator of cyclin D1 expression. Nakamura, Y., Grumont, R.J., Gerondakis, S. Mol. Cell. Biol. (2002) [Pubmed]
  27. Functional involvement of Akt signaling downstream of Jak1 in v-Abl-induced activation of hematopoietic cells. Oki, S., Limnander, A., Danial, N.N., Rothman, P.B. Blood (2002) [Pubmed]
  28. c-fos is not essential for v-abl-induced lymphomagenesis. Saez, E., Oppenheim, H., Smoluk, J., Andersen, J.W., Van Etten, R.A., Spiegelman, B.M. Cancer Res. (1995) [Pubmed]
  29. The Ig VH repertoire of fetal liver-derived pre-B cells is influenced by the expression of a gene linked to X-linked immune deficiency. Osman, G.E., Brodeur, P.H., Rosenberg, N., Wortis, H.H. J. Immunol. (1992) [Pubmed]
  30. Increased expression of Bcl-xL and c-Myc is associated with transformation by Abelson murine leukemia virus. Noronha, E.J., Sterling, K.H., Calame, K.L. J. Biol. Chem. (2003) [Pubmed]
  31. Novel recombinations of the IG kappa-locus that result in allelic exclusion. Feddersen, R.M., Martin, D.J., Van Ness, B.G. J. Immunol. (1990) [Pubmed]
  32. Highly specific characterization of tyrosine phosphoproteins in tumor cells based on monoclonal antibodies defined by conjugated phosphotyramine. Steinhilber, G., Sproll, M.W., Wolff, J.M., Anderer, F.A. Anticancer Res. (1990) [Pubmed]
WikiGenes - Universities