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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Distemper


High impact information on Distemper


Chemical compound and disease context of Distemper

  • In contrast, ILMC in canine distemper virus Snyder Hill-infected dogs began at 10 days p.i., peaked by 14 to 17 days p.i., and approached preinoculation levels by 28 days p.i. Antiviral immunity as measured by ILMC appears to be a critical factor in determining the outcome in canine distemper virus-infected hosts [10].
  • The polypeptides induced by canine distemper virus (CDV) strains have been characterized by polyacrylamide slab gel electrophoresis of infected cell lysates labelled with 35S-methionine, 14C-amino acids, 3H-glucosamine and 3H-mannose, or 32P-orthophosphate [11].
  • Fecal IgA and canine distemper virus (CDV) vaccine-specific circulating IgG and IgA were higher in the group receiving the probiotic than in controls [12].
  • Furthermore, induction of Scrg1 protein was observed in the brain of mice injured by canine distemper virus or gold thioglucose treatment [13].
  • Formalin-fixed brain tissues from 16 dogs with naturally occurring canine distemper virus (CDV) infection were investigated immunohistochemically by a panel of eight monoclonal antibodies (mAb) directed against four structural CDV proteins [14].

Biological context of Distemper


Anatomical context of Distemper


Gene context of Distemper


Analytical, diagnostic and therapeutic context of Distemper


  1. Antigenic relationships between measles and canine distemper viruses: comparison of immune response in animals and humans to individual virus-specific polypeptides. Stephenson, J.R., ter Meulen, V. Proc. Natl. Acad. Sci. U.S.A. (1979) [Pubmed]
  2. Alteration in phospholipid methylation and impairment of signal transmission in persistently paramyxovirus-infected C6 rat glioma cells. Münzel, P., Koschel, K. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  3. Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bone. Birch, M.A., Taylor, W., Fraser, W.D., Ralston, S.H., Hart, C.A., Gallagher, J.A. J. Bone Miner. Res. (1994) [Pubmed]
  4. Measles and canine distemper antibody. Presence in sera from patients with multiple sclerosis and matched control subjects. Madden, D.L., Wallen, W.C., Houff, S.A., Shekarchi, I.C., Leinikki, P.O., Castellano, G.A., Sever, J.L. Arch. Neurol. (1981) [Pubmed]
  5. Comparison of messenger RNAs induced in cells infected with each member of the morbillivirus group. Barrett, T., Underwood, B. Virology (1985) [Pubmed]
  6. Multiple sclerosis and canine distemper on Key West, Florida. Cook, S.D., Blumberg, B., Dowling, P.C., Deans, W., Cross, R. Lancet (1987) [Pubmed]
  7. Nearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells. von Messling, V., Oezguen, N., Zheng, Q., Vongpunsawad, S., Braun, W., Cattaneo, R. J. Virol. (2005) [Pubmed]
  8. Canine distemper virus and measles virus fusion glycoprotein trimers: partial membrane-proximal ectodomain cleavage enhances function. von Messling, V., Milosevic, D., Devaux, P., Cattaneo, R. J. Virol. (2004) [Pubmed]
  9. Morbillivirus infection of the mouse central nervous system induces region-specific upregulation of MMPs and TIMPs correlated to inflammatory cytokine expression. Khuth, S.T., Akaoka, H., Pagenstecher, A., Verlaeten, O., Belin, M.F., Giraudon, P., Bernard, A. J. Virol. (2001) [Pubmed]
  10. Lymphocyte-mediated immune cytotoxicity in dogs infected with virulent canine distemper virus. Appel, M.J., Shek, W.R., Summers, B.A. Infect. Immun. (1982) [Pubmed]
  11. A comparison of measles and canine distemper virus polypeptides. Campbell, J.J., Cosby, S.L., Scott, J.K., Rima, B.K., Martin, S.J., Appel, M. J. Gen. Virol. (1980) [Pubmed]
  12. Supplementation of food with Enterococcus faecium (SF68) stimulates immune functions in young dogs. Benyacoub, J., Czarnecki-Maulden, G.L., Cavadini, C., Sauthier, T., Anderson, R.E., Schiffrin, E.J., von der Weid, T. J. Nutr. (2003) [Pubmed]
  13. Scrg1 is induced in TSE and brain injuries, and associated with autophagy. Dron, M., Bailly, Y., Beringue, V., Haeberlé, A.M., Griffond, B., Risold, P.Y., Tovey, M.G., Laude, H., Dandoy-Dron, F. Eur. J. Neurosci. (2005) [Pubmed]
  14. Naturally occurring canine distemper virus encephalitis: distribution and expression of viral polypeptides in nervous tissues. Baumgärtner, W., Orvell, C., Reinacher, M. Acta Neuropathol. (1989) [Pubmed]
  15. Phosphorylation of canine distemper virus P protein by protein kinase C-zeta and casein kinase II. Liu, Z., Huntley, C.C., De, B.P., Das, T., Banerjee, A.K., Oglesbee, M.J. Virology (1997) [Pubmed]
  16. Cloning and expression of the nucleocapsid gene of virulent Kabete O strain of rinderpest virus in baculovirus: use in differential diagnosis between vaccinated and infected animals. Ismail, T., Ahmad, S., D'Souza-Ault, M., Bassiri, M., Saliki, J., Mebus, C., Yilma, T. Virology (1994) [Pubmed]
  17. Up-regulation of the hyaluronate receptor CD44 in canine distemper demyelinated plaques. Alldinger, S., Fonfara, S., Kremmer, E., Baumgärtner, W. Acta Neuropathol. (2000) [Pubmed]
  18. Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis. Alldinger, S., Wünschmann, A., Baumgärtner, W., Voss, C., Kremmer, E. Acta Neuropathol. (1996) [Pubmed]
  19. Pneumonia in Ottoman vipers (Vipera xanthena xanthena) associated with a parainfluenza 2-like virus. Potgieter, L.N., Sigler, R.E., Russell, R.G. J. Wildl. Dis. (1987) [Pubmed]
  20. Inhibition of tyrosine hydroxylase expression within the substantia nigra of mice infected with canine distemper virus. Bencsik, A., Akaoka, H., Giraudon, P., Belin, M.F., Bernard, A. J. Neuropathol. Exp. Neurol. (1997) [Pubmed]
  21. Non-cytocidal infection of keratinocytes by canine distemper virus in the so-called hard pad disease of canine distemper. Gröne, A., Groeters, S., Koutinas, A., Saridomichelakis, M., Baumgärtner, W. Vet. Microbiol. (2003) [Pubmed]
  22. Pagetic osteoclasts formed in vitro: absence of paracrystalline inclusions. Roodman, G.D., Ohsaki, Y., Miller, M.M., Demulder, A., Hosking, D., Singer, F.R., McManus, L.M. J. Submicrosc. Cytol. Pathol. (1998) [Pubmed]
  23. Antibodies to CD9, a tetraspan transmembrane protein, inhibit canine distemper virus-induced cell-cell fusion but not virus-cell fusion. Schmid, E., Zurbriggen, A., Gassen, U., Rima, B., ter Meulen, V., Schneider-Schaulies, J. J. Virol. (2000) [Pubmed]
  24. Vaccinia virus recombinants expressing either the measles virus fusion or hemagglutinin glycoprotein protect dogs against canine distemper virus challenge. Taylor, J., Pincus, S., Tartaglia, J., Richardson, C., Alkhatib, G., Briedis, D., Appel, M., Norton, E., Paoletti, E. J. Virol. (1991) [Pubmed]
  25. Measles virus and canine distemper virus target proteins into a TAP-independent MHC class I-restricted antigen-processing pathway. Neumeister, C., Nanan, R., Cornu, T., Lüder, C., ter Meulen, V., Naim, H., Niewiesk, S. J. Gen. Virol. (2001) [Pubmed]
  26. Demyelinating canine distemper encephalomyelitis: measurement of myelin basic protein in cerebrospinal fluid. Summers, B.A., Whitaker, J.N., Appel, M.J. J. Neuroimmunol. (1987) [Pubmed]
  27. In situ hybridization of virulent canine distemper virus in brain tissue, using digoxigenin-labeled probes. Zurbriggen, A., Müller, C., Vandevelde, M. Am. J. Vet. Res. (1993) [Pubmed]
  28. Canine distemper virus in Lake Baikal seals (Phoca sibirica). Mamaev, L.V., Visser, I.K., Belikov, S.I., Denikina, N.N., Harder, T., Goatley, L., Rima, B., Edginton, B., Osterhaus, A.D., Barrett, T. Vet. Rec. (1996) [Pubmed]
  29. Immunosuppression by canine distemper virus: modulation of in vitro immunoglobulin synthesis, interleukin release and prostaglandin E2 production. Krakowka, S., Ringler, S.S., Lewis, M., Olsen, R.G., Axthelm, M.K. Vet. Immunol. Immunopathol. (1987) [Pubmed]
  30. A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection of canine distemper virus RNA in Paget's disease. Hoyland, J.A., Dixon, J.A., Berry, J.L., Davies, M., Selby, P.L., Mee, A.P. J. Virol. Methods (2003) [Pubmed]
  31. Acute ataxia in a young ferret following canine distemper vaccination. Renal failure after epinephrine overdose. Donnelly, T.M., Orcutt, C.J. Lab animal. (2001) [Pubmed]
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