The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Phosphate-32     phosphate

Synonyms: Phosphate-32P, trioxido(oxo)-, AC1L50FN, [32P]-Pi, [32P]Pi, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of phosphate


High impact information on phosphate


Chemical compound and disease context of phosphate


Biological context of phosphate

  • The gradual addition of netropsin to poly(dA-dT) results in structural perturbations extending into the antibiotic-free base pair regions that begin to level off above 0.02 antibiotic molecules per polynucleotide phosphate (P/D = 50) [5].
  • The activation by FA was not paralleled by an incorporation of [32P]-phosphate into the ATP x Mg-dependent phosphatase, and from the kinetics of activation a protein-protein interaction with ATP x Mg as a necessary factor, can be inferred as the mechanism of activation [16].
  • Initial products of photophosphorylation with AMP and [32P]Pi [17].
  • The turnover of phosphate groups on NF-L during axonal transport was determined after the neurofilaments in retinal ganglion cells were phosphorylated in vivo by injecting mice intravitreally with [32P]orthophosphate [18].
  • However, the specific activity of ATP extracted from macrophages labeled with [32P]Pi during phagocytosis was 40% lower than ATP extracted from control cells [19].

Anatomical context of phosphate


Associations of phosphate with other chemical compounds


Gene context of phosphate


Analytical, diagnostic and therapeutic context of phosphate


  1. Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genome. Stow, N.D. EMBO J. (1982) [Pubmed]
  2. Fibronectin from chicken embryo fibroblasts contains covalently bound phosphate. Teng, M.H., Rifkin, D.B. J. Cell Biol. (1979) [Pubmed]
  3. Rapid phosphorylation of the L-myc protein induced by phorbol ester tumor promoters and serum. Saksela, K., Mäkelä, T.P., Evan, G., Alitalo, K. EMBO J. (1989) [Pubmed]
  4. Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I. Jones, J.I., D'Ercole, A.J., Camacho-Hubner, C., Clemmons, D.R. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  5. Netropsin-poly(dA-dT) complex in solution: structure and dynamics of antibiotic-free base pair regions and those centered on bound netropsin. Patel, D.J., Canuel, L.L. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  6. Chemoattractant-elicited increases in myosin phosphorylation in Dictyostelium. Berlot, C.H., Spudich, J.A., Devreotes, P.N. Cell (1985) [Pubmed]
  7. A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. Ben-Chetrit, E., Chan, E.K., Sullivan, K.F., Tan, E.M. J. Exp. Med. (1988) [Pubmed]
  8. FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase. Worthen, G.S., Avdi, N., Buhl, A.M., Suzuki, N., Johnson, G.L. J. Clin. Invest. (1994) [Pubmed]
  9. Insulin regulates apolipoprotein B turnover and phosphorylation in rat hepatocytes. Jackson, T.K., Salhanick, A.I., Elovson, J., Deichman, M.L., Amatruda, J.M. J. Clin. Invest. (1990) [Pubmed]
  10. Calcium/calmodulin-mediated action of calcitonin on lipid metabolism in rats. Nishizawa, Y., Okui, Y., Inaba, M., Okuno, S., Yukioka, K., Miki, T., Watanabe, Y., Morii, H. J. Clin. Invest. (1988) [Pubmed]
  11. Nucleolar phosphoproteins of normal rat liver and Novikoff hepatoma ascites cells. Kang, Y.J., Olson, M.O., Jones, C., Busch, H. Cancer Res. (1975) [Pubmed]
  12. Selective antiviral agents. The metabolism of 5-propyl-2'-deoxyuridine and effects on DNA synthesis in herpes simplex virus type 1 infections. Ruth, J.L., Cheng, Y. J. Biol. Chem. (1982) [Pubmed]
  13. Protein phosphorylation in normal and neoplastic development. Phosphorylation of proteins endogenous to foetal tissues and tumours. Malkinson, A.M., McSwigan, C.E. Biochem. J. (1978) [Pubmed]
  14. Herpes simplex virus-1-specific proteins are involved in alteration of polyphosphoinositide metabolism in baby-hamster kidney cells. Langeland, N., Moore, L.J., Holmsen, H., Haarr, L. Biochem. J. (1989) [Pubmed]
  15. Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20). Berry-Kravis, E., Kazmierczak, B.I., Derechin, V., Dawson, G. J. Neurochem. (1988) [Pubmed]
  16. ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. I. Purification of the enzyme and its regulation by the interaction with an activating protein factor. Yang, S.D., Vandenheede, J.R., Goris, J., Merlevede, W. J. Biol. Chem. (1980) [Pubmed]
  17. Initial products of photophosphorylation with AMP and [32P]Pi. Horner, R.D., Froehlich, J.P., Moudrianakis, E.N. J. Biol. Chem. (1983) [Pubmed]
  18. Identification of Ser-55 as a major protein kinase A phosphorylation site on the 70-kDa subunit of neurofilaments. Early turnover during axonal transport. Sihag, R.K., Nixon, R.A. J. Biol. Chem. (1991) [Pubmed]
  19. Increased ATP and creatine phosphate turnover in phagocytosing mouse peritoneal macrophages. Loike, J.D., Kozler, V.F., Silverstein, S.C. J. Biol. Chem. (1979) [Pubmed]
  20. Phosphorylation of chlamydomonas reinhardi chloroplast membrane proteins in vivo and in vitro. Owens, G.C., Ohad, I. J. Cell Biol. (1982) [Pubmed]
  21. Phosphorylation of Okazaki-like DNA fragments in mammalian cells and role of polyamines in the processing of this DNA. Pohjanpelto, P., Hölttä, E. EMBO J. (1996) [Pubmed]
  22. Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments. Lewis, S.E., Nixon, R.A. J. Cell Biol. (1988) [Pubmed]
  23. Correlation between changes in light energy distribution and changes in thylakoid membrane polypeptide phosphorylation in Chlamydomonas reinhardtii. Wollman, F.A., Delepelaire, P. J. Cell Biol. (1984) [Pubmed]
  24. Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles. Dillman, J.F., Pfister, K.K. J. Cell Biol. (1994) [Pubmed]
  25. Dual regulation of intermediate filament phosphorylation. Gilmartin, M.E., Mitchell, J., Vidrich, A., Freedberg, I.M. J. Cell Biol. (1984) [Pubmed]
  26. Transfer of adenine nucleotides between the releasable and nonreleasable compartments of rabbit blood platelets. Reimers, H.J., Mustard, J.F., Packham, M.A. J. Cell Biol. (1975) [Pubmed]
  27. A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'. Watts, A.D., Hunt, N.H., Wanigasekara, Y., Bloomfield, G., Wallach, D., Roufogalis, B.D., Chaudhri, G. EMBO J. (1999) [Pubmed]
  28. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. Stadel, J.M., Nambi, P., Shorr, R.G., Sawyer, D.F., Caron, M.G., Lefkowitz, R.J. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  29. Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells. Häring, H.U., White, M.F., Machicao, F., Ermel, B., Schleicher, E., Obermaier, B. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  30. Phosphorylation of RAS1 and RAS2 proteins in Saccharomyces cerevisiae. Cobitz, A.R., Yim, E.H., Brown, W.R., Perou, C.M., Tamanoi, F. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  31. Association of the p85 regulatory subunit of phosphatidylinositol 3-kinase with an essential erythropoietin receptor subdomain. He, T.C., Zhuang, H., Jiang, N., Waterfield, M.D., Wojchowski, D.M. Blood (1993) [Pubmed]
  32. Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma-associated proteins. Characterization of a c-Src-dependent 97-kD protein in vascular smooth muscle cells. Schmitz, U., Ishida, M., Berk, B.C. Circ. Res. (1997) [Pubmed]
  33. Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. Camp, H.S., Tafuri, S.R. J. Biol. Chem. (1997) [Pubmed]
  34. Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta. Burchfield, J.G., Lennard, A.J., Narasimhan, S., Hughes, W.E., Wasinger, V.C., Corthals, G.L., Okuda, T., Kondoh, H., Biden, T.J., Schmitz-Peiffer, C. J. Biol. Chem. (2004) [Pubmed]
  35. A lens intercellular junction protein, MP26, is a phosphoprotein. Johnson, K.R., Lampe, P.D., Hur, K.C., Louis, C.F., Johnson, R.G. J. Cell Biol. (1986) [Pubmed]
  36. The phosphorylation of coated membrane proteins in intact neurons. Keen, J.H., Black, M.M. J. Cell Biol. (1986) [Pubmed]
  37. Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP. Miles, K., Anthony, D.T., Rubin, L.L., Greengard, P., Huganir, R.L. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  38. Yeast invertase polymorphism is correlated with variable states of oligosaccharide chain phosphorylation. Frevert, J., Ballou, C.E. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
WikiGenes - Universities