Gene Review:
CXCL13 - chemokine (C-X-C motif) ligand 13
Homo sapiens
Synonyms:
ANGIE, ANGIE2, Angie, B cell-attracting chemokine 1, B lymphocyte chemoattractant, ...
- Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma. Smith, J.R., Braziel, R.M., Paoletti, S., Lipp, M., Uguccioni, M., Rosenbaum, J.T. Blood (2003)
- Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis. Carlsen, H.S., Baekkevold, E.S., Morton, H.C., Haraldsen, G., Brandtzaeg, P. Blood (2004)
- Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection. Widney, D.P., Breen, E.C., Boscardin, W.J., Kitchen, S.G., Alcantar, J.M., Smith, J.B., Zack, J.A., Detels, R., Martínez-Maza, O. J. Interferon Cytokine Res. (2005)
- Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Krumbholz, M., Theil, D., Cepok, S., Hemmer, B., Kivisäkk, P., Ransohoff, R.M., Hofbauer, M., Farina, C., Derfuss, T., Hartle, C., Newcombe, J., Hohlfeld, R., Meinl, E. Brain (2006)
- A preliminary study of a cartoon measure for children's reactions to chronic trauma. Praver, F., DiGiuseppe, R., Pelcovitz, D., Mandel, F.S., Gaines, R. Child maltreatment. (2000)
- CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. Schaerli, P., Willimann, K., Lang, A.B., Lipp, M., Loetscher, P., Moser, B. J. Exp. Med. (2000)
- B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. Legler, D.F., Loetscher, M., Roos, R.S., Clark-Lewis, I., Baggiolini, M., Moser, B. J. Exp. Med. (1998)
- BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma. Mazzucchelli, L., Blaser, A., Kappeler, A., Schärli, P., Laissue, J.A., Baggiolini, M., Uguccioni, M. J. Clin. Invest. (1999)
- CXCL12 (SDF-1) and CXCL13 (BCA-1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients. Lisignoli, G., Toneguzzi, S., Piacentini, A., Cristino, S., Grassi, F., Cavallo, C., Facchini, A. J. Cell. Physiol. (2006)
- Distinct transcriptional programs activated by interleukin-10 with or without lipopolysaccharide in dendritic cells: induction of the B cell-activating chemokine, CXC chemokine ligand 13. Perrier, P., Martinez, F.O., Locati, M., Bianchi, G., Nebuloni, M., Vago, G., Bazzoni, F., Sozzani, S., Allavena, P., Mantovani, A. J. Immunol. (2004)
- Selectively frequent expression of CXCR5 enhances resistance to apoptosis in CD8(+)CD34(+) T cells from patients with T-cell-lineage acute lymphocytic leukemia. Qiuping, Z., Jie, X., Youxin, J., Qun, W., Wei, J., Chun, L., Jin, W., Yan, L., Chunsong, H., Mingzhen, Y., Qingping, G., Qun, L., Kejian, Z., Zhimin, S., Junyan, L., Jinquan, T. Oncogene (2005)
- CXCL13 (BCA-1) is produced by follicular lymphoma cells: role in the accumulation of malignant B cells. Husson, H., Freedman, A.S., Cardoso, A.A., Schultze, J., Munoz, O., Strola, G., Kutok, J., Carideo, E.G., De Beaumont, R., Caligaris-Cappio, F., Ghia, P. Br. J. Haematol. (2002)
- Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia. Bürkle, A., Niedermeier, M., Schmitt-Gräff, A., Wierda, W.G., Keating, M.J., Burger, J.A. Blood (2007)
- Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor. Jenh, C.H., Cox, M.A., Hipkin, W., Lu, T., Pugliese-Sivo, C., Gonsiorek, W., Chou, C.C., Narula, S.K., Zavodny, P.J. Cytokine (2001)
- Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype. Dengler, T.J., Pober, J.S. J. Immunol. (2000)
- Regulatory role of the N terminus of the vacuolar calcium-ATPase in cauliflower. Malmström, S., Akerlund, H.E., Askerlund, P. Plant Physiol. (2000)
- Electrical and chemical stimulation of the basolateral complex of the amygdala reinstates cocaine-seeking behavior in the rat. Hayes, R.J., Vorel, S.R., Spector, J., Liu, X., Gardner, E.L. Psychopharmacology (Berl.) (2003)
- BLC (CXCL13) is expressed by different dendritic cell subsets in vitro and in vivo. Vissers, J.L., Hartgers, F.C., Lindhout, E., Figdor, C.G., Adema, G.J. Eur. J. Immunol. (2001)
- Developmental stage-specific shift in responsiveness to chemokines during human B-cell development. Honczarenko, M., Glodek, A.M., Swierkowski, M., Na, I.K., Silberstein, L.E. Exp. Hematol. (2006)
- A role for chemokines in the induction of chondrocyte phenotype modulation. Mazzetti, I., Magagnoli, G., Paoletti, S., Uguccioni, M., Olivotto, E., Vitellozzi, R., Cattini, L., Facchini, A., Borzì, R.M. Arthritis Rheum. (2004)
- The chemokine CXCL13 (BCA-1) inhibits FGF-2 effects on endothelial cells. Spinetti, G., Camarda, G., Bernardini, G., Romano Di Peppe, S., Capogrossi, M.C., Napolitano, M. Biochem. Biophys. Res. Commun. (2001)
- Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors. Piqueras, B., Connolly, J., Freitas, H., Palucka, A.K., Banchereau, J. Blood (2006)
- Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjögren's syndrome. Salomonsson, S., Larsson, P., Tengnér, P., Mellquist, E., Hjelmström, P., Wahren-Herlenius, M. Scand. J. Immunol. (2002)
- BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection. Steinmetz, O.M., Panzer, U., Kneissler, U., Harendza, S., Lipp, M., Helmchen, U., Stahl, R.A. Kidney Int. (2005)