Gene Review:
CXCR5 - chemokine (C-X-C motif) receptor 5
Homo sapiens
Synonyms:
BLR1, Burkitt lymphoma receptor 1, C-X-C chemokine receptor type 5, CD185, CXC-R5, ...
- B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. Legler, D.F., Loetscher, M., Roos, R.S., Clark-Lewis, I., Baggiolini, M., Moser, B. J. Exp. Med. (1998)
- A CXC chemokine receptor, CXCR5/BLR1, is a novel and specific coreceptor for human immunodeficiency virus type 2. Kanbe, K., Shimizu, N., Soda, Y., Takagishi, K., Hoshino, H. Virology (1999)
- Selectively frequent expression of CXCR5 enhances resistance to apoptosis in CD8(+)CD34(+) T cells from patients with T-cell-lineage acute lymphocytic leukemia. Qiuping, Z., Jie, X., Youxin, J., Qun, W., Wei, J., Chun, L., Jin, W., Yan, L., Chunsong, H., Mingzhen, Y., Qingping, G., Qun, L., Kejian, Z., Zhimin, S., Junyan, L., Jinquan, T. Oncogene (2005)
- A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Gunn, M.D., Ngo, V.N., Ansel, K.M., Ekland, E.H., Cyster, J.G., Williams, L.T. Nature (1998)
- CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. Schaerli, P., Willimann, K., Lang, A.B., Lipp, M., Loetscher, P., Moser, B. J. Exp. Med. (2000)
- Autoantigens act as tissue-specific chemoattractants. Oppenheim, J.J., Dong, H.F., Plotz, P., Caspi, R.R., Dykstra, M., Pierce, S., Martin, R., Carlos, C., Finn, O., Koul, O., Howard, O.M. J. Leukoc. Biol. (2005)
- Expression of the G-protein--coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells. Förster, R., Emrich, T., Kremmer, E., Lipp, M. Blood (1994)
- BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection. Steinmetz, O.M., Panzer, U., Kneissler, U., Harendza, S., Lipp, M., Helmchen, U., Stahl, R.A. Kidney Int. (2005)
- Sequence variation of a novel heptahelical leucocyte receptor through alternative transcript formation. Barella, L., Loetscher, M., Tobler, A., Baggiolini, M., Moser, B. Biochem. J. (1995)
- Ectopic expression of CXCR5/BLR1 accelerates retinoic acid- and vitamin D(3)-induced monocytic differentiation of U937 cells. Battle, T.E., Yen, A. Exp. Biol. Med. (Maywood) (2002)
- A general method for screening mAbs specific for G-protein coupled receptors as exemplified by using epitope tagged BLR1-transfected 293 cells and solid-phase cell ELISA. Förster, R., Emrich, T., Voss, C., Lipp, M. Biochem. Biophys. Res. Commun. (1993)
- BLR-1 and BLR-2, key regulatory elements of photoconidiation and mycelial growth in Trichoderma atroviride. Casas-Flores, S., Rios-Momberg, M., Bibbins, M., Ponce-Noyola, P., Herrera-Estrella, A. Microbiology (Reading, Engl.) (2004)
- Molecular cloning of bovine chemokine receptors and expression by WC1+ gammadelta T cells. Blumerman, S.L., Wang, F., Herzig, C.T., Baldwin, C.L. Dev. Comp. Immunol. (2007)
- Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate. Howard, O.M., Dong, H.F., Su, S.B., Caspi, R.R., Chen, X., Plotz, P., Oppenheim, J.J. Blood (2005)
- Expression and regulation of chemokine receptors in human natural killer cells. Inngjerdingen, M., Damaj, B., Maghazachi, A.A. Blood (2001)
- Cutting edge: induction of follicular homing precedes effector Th cell development. Schaerli, P., Loetscher, P., Moser, B. J. Immunol. (2001)