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MeSH Review

Liver Neoplasms, Experimental

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Disease relevance of Liver Neoplasms, Experimental


High impact information on Liver Neoplasms, Experimental


Chemical compound and disease context of Liver Neoplasms, Experimental


Biological context of Liver Neoplasms, Experimental


Anatomical context of Liver Neoplasms, Experimental


Gene context of Liver Neoplasms, Experimental

  • Demonstration of a specific clearance receptor for tissue-type plasminogen activator on rat Novikoff hepatoma cells [25].
  • The ETA receptor density was significantly elevated, whereas the density of the ETB receptor was decreased in Morris hepatoma 7777 [26].
  • The aim of the present study was the comparative analysis of morphological changes found in the lungs of Buffalo rats in the course of Morris hepatoma 5123 after i.t. treatment with recombinant human TNF-alpha (rhTNF-alpha) and its muteins [27].
  • RNA from a rat liver tumor (Morris hepatoma 5123tc) was used to construct cDNAs together comprising the complete coding sequence of rat oncomodulin mRNA [28].
  • However, the quantity of nucleophosmin mRNA is 50- and 5-fold higher in Novikoff hepatoma and hypertrophic rat liver, respectively, when compared with normal rat liver [29].

Analytical, diagnostic and therapeutic context of Liver Neoplasms, Experimental


  1. Tumour-specific phenylalanine tRNA contains two supernumerary methylated bases. Kuchino, Y., Borek, E. Nature (1978) [Pubmed]
  2. Loss of reciprocal modulations of growth and liver function of hepatoma cells in culture by contact with cells or cell membranes. Nakamura, T., Nakayama, Y., Teramoto, H., Nawa, K., Ichihara, A. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  3. In vivo lactate production and utilization by Jensen sarcoma and Morris hepatoma 7288CTC. Sauer, L.A., Dauchy, R.T. Cancer Res. (1986) [Pubmed]
  4. The mechanism of 5-fluorouridine toxicity in Novikoff hepatoma cells. Wilkinson, D.S., Crumley, J. Cancer Res. (1976) [Pubmed]
  5. Involvement of histamine in growth of mouse and rat tumors: antitumoral properties of monofluoromethylhistidine, an enzyme-activated irreversible inhibitor of histidine decarboxylase. Bartholeyns, J., Bouclier, M. Cancer Res. (1984) [Pubmed]
  6. Dictyostelium small nuclear RNA D2 is homologous to rat nucleolar RNA U3 and is encoded by a dispersed multigene family. Wise, J.A., Weiner, A.M. Cell (1980) [Pubmed]
  7. Increased urinary excretion of cyclic guanosine monophosphate in rats bearing Morris hepatoma 3924A. Murad, F., Kimura, H., Hopkins, H.A., Looney, W.B., Kovacs, C.J. Science (1975) [Pubmed]
  8. In vitro inhibition of tritiated thymidine uptake in Morris hepatoma cells by normal rat liver extract: a possible liver chalone. Kuo, C.Y., Yoo, T.J. J. Natl. Cancer Inst. (1977) [Pubmed]
  9. Estrogen binding protein activity in Morris hepatoma 7777 compared with normal rat liver. Francavilla, A., Eagon, P.K., DiLeo, A., Van Thiel, D.H., Ove, P., Wu, S.K., Sax, S.A., Starzl, T.E. Gastroenterology (1984) [Pubmed]
  10. Inhibition of the growth of Morris hepatoma No. 44 in rats after induction of hypothyroidism: evidence that Morris hepatomas are thyroid dependent. Mishkin, S., Morris, H.P., Yalovsky, M.A., Murthy, P.V. Gastroenterology (1979) [Pubmed]
  11. Interaction of Na+ and K+ transport with aerobic energy metabolism in slices of Morris hepatoma 3924A. Galeotti, T., van Rossum, G.D., Russo, M.A., Palombini, G. Cancer Res. (1976) [Pubmed]
  12. Transport of pyruvate in mitochondria from different tumor cells. Paradies, G., Capuano, F., Palombini, G., Galeotti, T., Papa, S. Cancer Res. (1983) [Pubmed]
  13. Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells. Cory, J.G., Breland, J.C., Carter, G.L. Cancer Res. (1979) [Pubmed]
  14. Comparative ultrastructural studies of nucleoli of tumor cells treated with adriamycin and the newer anthracyclines, carminomycin and marcellomycin. Daskal, Y., Woodard, C., Crooke, S.T., Busch, H. Cancer Res. (1978) [Pubmed]
  15. Blocking late cholesterol biosynthesis inhibits the growth of transplanted Morris hepatomas (7288CTC) in rats. Xu, G., Salen, G., Lea, M., Tint, G.S., Nguyen, L.B., Batta, A.K., Chen, T.S., Shefer, S. Hepatology (1996) [Pubmed]
  16. Alterations in chromatin conformation are accompanied by reorganization of nonchromatin domains that contain U-snRNP protein p28 and nuclear protein p107. Smith, H.C., Spector, D.L., Woodcock, C.L., Ochs, R.L., Bhorjee, J. J. Cell Biol. (1985) [Pubmed]
  17. Uridine kinase activities and pyrimidine nucleoside phosphorylation in fluoropyrimidine-sensitive and -resistant cell lines of the Novikoff hepatoma. Greenberg, N., Schumm, D.E., Webb, T.E. Biochem. J. (1977) [Pubmed]
  18. Studies on lipid peroxidation in normal and tumour tissues. The Yoshida rat liver tumour. Cheeseman, K.H., Emery, S., Maddix, S.P., Slater, T.F., Burton, G.W., Ingold, K.U. Biochem. J. (1988) [Pubmed]
  19. Increased MIBG uptake after transfer of the human norepinephrine transporter gene in rat hepatoma. Altmann, A., Kissel, M., Zitzmann, S., Kübler, W., Mahmut, M., Peschke, P., Haberkorn, U. J. Nucl. Med. (2003) [Pubmed]
  20. Efflux of adenine nucleotides in mitochondria from rat tumor cells of varying growth rates. Lau, B.W., Chan, S.H. Cancer Res. (1984) [Pubmed]
  21. Increased activity of low-Km cyclic adenosine 3':5'-monophosphate phosphodiesterase in plasma membranes of Morris hepatoma 5123tc (h). Hickie, R.A., Walker, C.M., Datta, A. Cancer Res. (1975) [Pubmed]
  22. Identification of polysomes synthesizing Novikoff hepatoma nucleolar antigens. Reiners, J.J., Davis, F.M., Busch, H. Cancer Res. (1980) [Pubmed]
  23. Membranous effects on adenosine triphosphatase activities of mitochondria from rat liver and Morris hepatoma 3924A. Melnick, R.L., Hanson, R.M., Morris, H.P. Cancer Res. (1977) [Pubmed]
  24. Interactions among mitochondrial aspartate aminotransferase, malate dehydrogenase, and the inner mitochondrial membrane from heart, hepatoma, and liver. Teller, J.K., Fahien, L.A., Valdivia, E. J. Biol. Chem. (1990) [Pubmed]
  25. Demonstration of a specific clearance receptor for tissue-type plasminogen activator on rat Novikoff hepatoma cells. Nguyen, G., Self, S.J., Camani, C., Kruithof, E.K. J. Biol. Chem. (1992) [Pubmed]
  26. The endothelin system in Morris hepatoma-7777: an endothelin receptor antagonist inhibits growth in vitro and in vivo. Pfab, T., Stoltenburg-Didinger, G., Trautner, C., Godes, M., Bauer, C., Hocher, B. Br. J. Pharmacol. (2004) [Pubmed]
  27. Comparative studies on the ultrastructure of the rat lungs after intratumor treatment of Morris hepatoma with rhTNF-alpha and its muteins. Terlikowski, S., Sulkowski, S., Sulkowska, M., Nowak, H.F. J. Submicrosc. Cytol. Pathol. (1999) [Pubmed]
  28. A complete complementary DNA for the oncodevelopmental calcium-binding protein, oncomodulin. Gillen, M.F., Banville, D., Rutledge, R.G., Narang, S., Seligy, V.L., Whitfield, J.F., MacManus, J.P. J. Biol. Chem. (1987) [Pubmed]
  29. Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth. Chan, W.Y., Liu, Q.R., Borjigin, J., Busch, H., Rennert, O.M., Tease, L.A., Chan, P.K. Biochemistry (1989) [Pubmed]
  30. Characterization of nucleolar antigens of normal rat liver, regenerating rat liver, and Novikoff ascites hepatoma cells following in vitro translation of polyadenylic acid-containing messenger RNA. Satoh, K., Busch, H. Cancer Res. (1983) [Pubmed]
  31. Subcellular localization of acetoacetate coenzyme A transferase in rat hepatomas. Fenselau, A., Wallis, K., Morris, H.P. Cancer Res. (1976) [Pubmed]
  32. Purification and partial characterization of nucleolar antigen-1 of the Novikoff hepatoma. Marashi, F., Davis, F.M., Busch, R.K., Savage, H.E., Busch, H. Cancer Res. (1979) [Pubmed]
  33. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Morris hepatoma 7800 after intravenous injection of mevalonic acid. George, R., Goldfarb, S. Cancer Res. (1980) [Pubmed]
  34. alpha-Fetoprotein gene expression. Control of alpha-fetoprotein mRNA levels in cultured rat hepatoma cells. Innis, M.A., Miller, D.L. J. Biol. Chem. (1979) [Pubmed]
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