Gene Review:
Ednra - endothelin receptor type A
Rattus norvegicus
Synonyms:
ET-A, ET-AR, Endor, Endothelin A receptor, Endothelin-1 receptor, ...
- Endothelin 1 does not play a major role in the homeostasis of arterial pressure in cirrhotic rats with ascites. Leivas, A., Jiménez, W., Lamas, S., Bosch-Marcé, M., Oriola, J., Clària, J., Arroyo, V., Rivera, F., Rodés, J. Gastroenterology (1995)
- Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater. Brändli, P., Löffler, B.M., Breu, V., Osterwalder, R., Maire, J.P., Clozel, M. Pain (1996)
- Endothelins stimulate cyclic AMP accumulation in the isolated rat anterior pituitary gland: possible involvement of ETA receptor activation and prostaglandin E2 production. Domae, M., Yamada, K., Inoue, T., Satoh, M., Furukawa, T. J. Pharmacol. Exp. Ther. (1994)
- The endothelin system in Morris hepatoma-7777: an endothelin receptor antagonist inhibits growth in vitro and in vivo. Pfab, T., Stoltenburg-Didinger, G., Trautner, C., Godes, M., Bauer, C., Hocher, B. Br. J. Pharmacol. (2004)
- Endothelin-1-evoked calcium transients in UMR-106 osteoblastic osteosarcoma cells are mediated through endothelin-A and endothelin-B receptors. Semler, D.E., Ohlstein, E.H., Nambi, P., Slater, C., Stern, P.H. J. Pharmacol. Exp. Ther. (1995)
- RGDN peptide interaction with endothelial alpha5beta1 integrin causes sustained endothelin-dependent vasoconstriction of rat skeletal muscle arterioles. Mogford, J.E., Davis, G.E., Meininger, G.A. J. Clin. Invest. (1997)
- Endothelin-3 induces hypertrophy of cardiomyocytes by the endogenous endothelin-1-mediated mechanism. Tamamori, M., Ito, H., Adachi, S., Akimoto, H., Marumo, F., Hiroe, M. J. Clin. Invest. (1996)
- Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing. Rockey, D.C., Chung, J.J. J. Clin. Invest. (1996)
- Osmolar regulation of endothelin signaling in rat renal medullary interstitial cells. Vernace, M.A., Mento, P.F., Maita, M.E., Girardi, E.P., Chang, M.D., Nord, E.P., Wilkes, B.M. J. Clin. Invest. (1995)
- Role of endothelin-1/endothelin receptor system in endotoxic shock rats. Ishimaru, S., Shichiri, M., Mineshita, S., Hirata, Y. Hypertens. Res. (2001)
- The role of atrial natriuretic peptide and endothelin in hypoxia induced pulmonary hypertension. Chen, Y.F., Li, H., Elton, T.S., Yang, R.H., Jin, H., Oparil, S. The Chinese journal of physiology. (1994)
- Regulation of endothelin-converting enzyme 1 in nephrotic syndrome in rats. Ikebe, M., Nonoguchi, H., Nakayama, Y., Tashima, Y., Shimada, K., Tanzawa, K., Tomita, K. Nephron Exp. Nephrol. (2003)
- Inotropic effects of endothelin-1: interaction with molsidomine and with BQ 610. Beyer, M.E., Slesak, G., Hövelborn, T., Kazmaier, S., Nerz, S., Hoffmeister, H.M. Hypertension (1999)
- Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activation. Ergul, A., Portik-Dobos, V., Giulumian, A.D., Molero, M.M., Fuchs, L.C. Am. J. Physiol. Heart Circ. Physiol. (2003)
- Endothelin-stimulated secretion of natriuretic peptides by rat atrial myocytes is mediated by endothelin A receptors. Thibault, G., Doubell, A.F., Garcia, R., Larivière, R., Schiffrin, E.L. Circ. Res. (1994)
- Coupling of endothelin B receptors to the calcium pump and phospholipase C via Gs and Gq in rat liver. Jouneaux, C., Mallat, A., Serradeil-Le Gal, C., Goldsmith, P., Hanoune, J., Lotersztajn, S. J. Biol. Chem. (1994)
- Endothelin receptor type A signals both the accumulation of inositol phosphates and the inhibition of cyclic AMP generation in rat myometrium: stimulation and desensitization. Khac, L.D., Naze, S., Harbon, S. Mol. Pharmacol. (1994)
- Endothelin B receptor-mediated vasoconstriction induced by endothelin A receptor antagonist. Zhang, Y., Oliver, J.R., Horowitz, J.D. Cardiovasc. Res. (1998)
- Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1. Housset, C., Rockey, D.C., Bissell, D.M. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Localization of functional endothelin receptor signaling complexes in cardiac transverse tubules. Robu, V.G., Pfeiffer, E.S., Robia, S.L., Balijepalli, R.C., Pi, Y., Kamp, T.J., Walker, J.W. J. Biol. Chem. (2003)
- Endothelin stimulates mitogen-activated protein kinase activity in mesangial cells through ETA. Wang, Y., Pouysségur, J., Dunn, M.J. J. Am. Soc. Nephrol. (1994)
- Endothelin A-receptor blockade worsens endotoxin-induced hepatic microcirculatory changes and necrosis. Nishida, T., Huang, T.P., Seiyama, A., Hamada, E., Kamiike, W., Ueshima, S., Kazuo, H., Matsuda, H. Gastroenterology (1998)
- Regulation of endothelin-A receptor sensitivity by cyclic adenosine monophosphate in rat hepatic stellate cells. Reinehr, R., Fischer, R., Häussinger, D. Hepatology (2002)
- Endothelin a receptor blockade and endothelin B receptor blockade improve hypokalemic nephropathy by different mechanisms. Suga, S., Yasui, N., Yoshihara, F., Horio, T., Kawano, Y., Kangawa, K., Johnson, R.J. J. Am. Soc. Nephrol. (2003)
- Intranephron distribution and regulation of endothelin-converting enzyme-1 in cyclosporin A-induced acute renal failure in rats. Nakayama, Y., Nonoguchi, H., Kiyama, S., Ikebe, M., Tashima, Y., Shimada, K., Tanzawa, K., Tomita, K. J. Am. Soc. Nephrol. (1999)
- Unique endothelin receptor binding in kidneys of ETB receptor deficient rats. Taylor, T.A., Gariepy, C.E., Pollock, D.M., Pollock, J.S. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2003)
- Role of endothelins in regulation of vascular tone in the in situ perfused rat adrenals. Mazzocchi, G., Malendowicz, L.K., Musajo, F.G., Gottardo, G., Markowska, A., Nussdorfer, G.G. Am. J. Physiol. (1998)
- Porphyromonas gingivalis lipopolysaccharide-induced up-regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation. Slomiany, B.L., Slomiany, A. IUBMB Life (2004)
- Effect of endothelin-3 on cytosolic calcium level in vascular endothelium and on smooth muscle contraction. Sudjarwo, S.A., Hori, M., Karaki, H. Eur. J. Pharmacol. (1992)
- Effects of endothelin receptor selective antagonists, BQ-123 and BQ-788, on IRL 1620 and endothelin-1 responses of airway and vascular preparations from rats. O'Donnell, S.R., Kay, C.S. Pulmonary pharmacology. (1995)
- Endothelin-1 inhibits secretin-stimulated ductal secretion by interacting with ETA receptors on large cholangiocytes. Caligiuri, A., Glaser, S., Rodgers, R.E., Phinizy, J.L., Robertson, W., Papa, E., Pinzani, M., Alpini, G. Am. J. Physiol. (1998)
- Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells. Owada, A., Tomita, K., Terada, Y., Sakamoto, H., Nonoguchi, H., Marumo, F. J. Clin. Invest. (1994)
- Endothelin ETA receptor antagonism does not attenuate angiotensin II-induced cardiac hypertrophy in vivo in rats. De Smet, H.R., Menadue, M.F., Oliver, J.R., Phillips, P.A. Clin. Exp. Pharmacol. Physiol. (2003)
- Endothelin A receptor blockade decreases expression of growth factors and collagen and improves matrix metalloproteinase-2 activity in kidneys from stroke-prone spontaneously hypertensive rats. Tostes, R.C., Touyz, R.M., He, G., Ammarguellat, F., Schiffrin, E.L. J. Cardiovasc. Pharmacol. (2002)
- Expression of endothelin-1, endothelin-3, endothelin-converting enzyme-1, and endothelin-A and endothelin-B receptor mRNA after angioplasty-induced neointimal formation in the rat. Wang, X., Douglas, S.A., Louden, C., Vickery-Clark, L.M., Feuerstein, G.Z., Ohlstein, E.H. Circ. Res. (1996)
- Actions of endothelins and sarafotoxin 6c in the rat isolated perfused lung. Lal, H., Woodward, B., Williams, K.I. Br. J. Pharmacol. (1995)
- The effect of castration on endothelins, their receptors and endothelin converting enzyme in rat prostate. Takahashi, W., Afiatpour, P., Jr Foster, H.E., Ikeda, K., Wada, Y., Weiss, R.M., Latifpour, J. Naunyn Schmiedebergs Arch. Pharmacol. (2002)