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MeSH Review

Giant Lymph Node Hyperplasia

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Disease relevance of Giant Lymph Node Hyperplasia


High impact information on Giant Lymph Node Hyperplasia


Chemical compound and disease context of Giant Lymph Node Hyperplasia


Biological context of Giant Lymph Node Hyperplasia


Anatomical context of Giant Lymph Node Hyperplasia


Gene context of Giant Lymph Node Hyperplasia


Analytical, diagnostic and therapeutic context of Giant Lymph Node Hyperplasia


  1. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. Brandt, S.J., Bodine, D.M., Dunbar, C.E., Nienhuis, A.W. J. Clin. Invest. (1990) [Pubmed]
  2. Human herpesvirus 8 infection in patients with POEMS syndrome-associated multicentric Castleman's disease. Bélec, L., Mohamed, A.S., Authier, F.J., Hallouin, M.C., Soe, A.M., Cotigny, S., Gaulard, P., Gherardi, R.K. Blood (1999) [Pubmed]
  3. Relation of follicular dendritic reticulum cells to Reed-Sternberg cells of Hodgkin's disease with emphasis on the expression of CD21 antigen. Delsol, G., Meggetto, F., Brousset, P., Cohen-Knafo, E., al Saati, T., Rochaix, P., Gorguet, B., Rubin, B., Voigt, J.J., Chittal, S. Am. J. Pathol. (1993) [Pubmed]
  4. Secretion of interleukin-6 and vascular endothelial growth factor by spindle cell sarcoma complicating Castleman's disease (so-called 'vascular neoplasia'). Kakiuchi, C., Ishida, T., Sato, H., Katano, H., Ishiko, T., Mukai, H., Kogi, M., Kasuga, N., Takeuchi, K., Yamane, K., Fukayama, M., Mori, S. J. Pathol. (2002) [Pubmed]
  5. Major histocompatibility complex class I molecules are down-regulated at the cell surface by the K5 protein encoded by Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8. Haque, M., Ueda, K., Nakano, K., Hirata, Y., Parravicini, C., Corbellino, M., Yamanishi, K. J. Gen. Virol. (2001) [Pubmed]
  6. Interleukin-6: from basic science to medicine--40 years in immunology. Kishimoto, T. Annu. Rev. Immunol. (2005) [Pubmed]
  7. Inactivation of the IL-6 gene prevents development of multicentric Castleman's disease in C/EBP beta-deficient mice. Screpanti, I., Musiani, P., Bellavia, D., Cappelletti, M., Aiello, F.B., Maroder, M., Frati, L., Modesti, A., Gulino, A., Poli, V. J. Exp. Med. (1996) [Pubmed]
  8. Retinoic acid for treatment of multicentric Castleman's disease. Rieu, P., Droz, D., Gessain, A., Grünfeld, J.P., Hermine, O. Lancet (1999) [Pubmed]
  9. Failure of cidofovir in HIV-associated multicentric Castleman disease. Berezne, A., Agbalika, F., Oksenhendler, E. Blood (2004) [Pubmed]
  10. High incidence of Kaposi sarcoma-associated herpesvirus-related non-Hodgkin lymphoma in patients with HIV infection and multicentric Castleman disease. Oksenhendler, E., Boulanger, E., Galicier, L., Du, M.Q., Dupin, N., Diss, T.C., Hamoudi, R., Daniel, M.T., Agbalika, F., Boshoff, C., Clauvel, J.P., Isaacson, P.G., Meignin, V. Blood (2002) [Pubmed]
  11. FDG-PET appearance of pelvic Castleman's disease. Murphy, S.P., Nathan, M.A., Karwal, M.W. J. Nucl. Med. (1997) [Pubmed]
  12. 2-Chloro-deoxyadenosine therapy for giant lymph node hyperplasia. Bordeleau, L., Bredeson, C., Markman, S. Br. J. Haematol. (1995) [Pubmed]
  13. Alleviation of systemic manifestations of multicentric Castleman's disease by thalidomide. Lee, F.C., Merchant, S.H. Am. J. Hematol. (2003) [Pubmed]
  14. Rapidly progressive renal failure associated with angiofollicular lymph node hyperplasia. Tsukamoto, Y., Hanada, N., Nomura, Y., Hiki, Y., Kasai, K., Shigematsu, H., Kobayashi, Y. American journal of nephrology. (1991) [Pubmed]
  15. A plasma cell variant of Castleman's disease treated successfully with cimetidine. Case report and review of the literature. Barbounis, V., Efremidis, A. Anticancer Res. (1996) [Pubmed]
  16. Ornithine decarboxylase gene expression in Castleman's disease. Malaguarnera, L., Pilastro, M.R., Vicari, L., Di Marco, R., Malaguarnera, M., Messina, A. J. Mol. Med. (1999) [Pubmed]
  17. Tropism of human herpesvirus 8 for peripheral blood lymphocytes in patients with Castleman's disease. Kikuta, H., Itakura, O., Taneichi, K., Kohno, M. Br. J. Haematol. (1997) [Pubmed]
  18. The POEMS syndrome among Chinese: association with Castleman's disease and some immunological abnormalities. Thajeb, P., Chee, C.Y., Lo, S.F., Lee, N. Acta neurologica Scandinavica. (1989) [Pubmed]
  19. Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy. Nishimoto, N., Sasai, M., Shima, Y., Nakagawa, M., Matsumoto, T., Shirai, T., Kishimoto, T., Yoshizaki, K. Blood (2000) [Pubmed]
  20. Hyaline vascular Castleman's disease with HMGIC rearrangement in follicular dendritic cells: molecular evidence of mesenchymal tumorigenesis. Cokelaere, K., Debiec-Rychter, M., De Wolf-Peeters, C., Hagemeijer, A., Sciot, R. Am. J. Surg. Pathol. (2002) [Pubmed]
  21. Immunodeficiency and IL-6 production by peripheral blood monocytes in multicentric Castleman's disease. Ishiyama, T., Nakamura, S., Akimoto, Y., Koike, M., Tomoyasu, S., Tsuruoka, N., Murata, Y., Sato, T., Wakabayashi, Y., Chiba, S. Br. J. Haematol. (1994) [Pubmed]
  22. Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretion. Mori, Y., Nishimoto, N., Ohno, M., Inagi, R., Dhepakson, P., Amou, K., Yoshizaki, K., Yamanishi, K. J. Med. Virol. (2000) [Pubmed]
  23. Expression of ICAM-1, VCAM-1 and ELAM-1 in angiofollicular lymph node hyperplasia (Castleman's disease): evidence for dysplasia of follicular dendritic reticulum cells. Ruco, L.P., Gearing, A.J., Pigott, R., Pomponi, D., Burgio, V.L., Cafolla, A., Baiocchini, A., Baroni, C.D. Histopathology (1991) [Pubmed]
  24. Interleukin-6: structure-function relationships. Simpson, R.J., Hammacher, A., Smith, D.K., Matthews, J.M., Ward, L.D. Protein Sci. (1997) [Pubmed]
  25. Anti-interleukin 6 receptor antibody treatment in rheumatic disease. Nishimoto, N., Kishimoto, T., Yoshizaki, K. Ann. Rheum. Dis. (2000) [Pubmed]
  26. Interleukin-6 receptor expression in the peripheral B cells of patients with multicentric Castleman's disease. Ishiyama, T., Koike, M., Nakamura, S., Kakimoto, T., Akimoto, Y., Tsuruoka, N. Ann. Hematol. (1996) [Pubmed]
  27. Multicentric Castleman's disease associated with rheumatoid arthritis: a possible role of hepatitis B antigen. Ben-Chetrit, E., Flusser, D., Okon, E., Ackerman, Z., Rubinow, A. Ann. Rheum. Dis. (1989) [Pubmed]
  28. Resolution of AIDS-related Castleman's disease with anti-CD20 monoclonal antibodies is associated with declining IL-6 and TNF-alpha levels. Newsom-Davis, T., Bower, M., Wildfire, A., Thirlwell, C., Nelson, M., Gazzard, B., Stebbing, J. Leuk. Lymphoma (2004) [Pubmed]
  29. Analysis of the human herpesvirus 8 (HHV-8) genome and HHV-8 vIL-6 expression in archival cases of castleman disease at low risk for HIV infection. Menke, D.M., Chadbum, A., Cesarman, E., Green, E., Berenson, J., Said, J., Tiemann, M., Parwaresch, R., Thome, S.D. Am. J. Clin. Pathol. (2002) [Pubmed]
  30. Aggressive angiofollicular lymph node hyperplasia (Castleman's disease) treated with high dose melphalan and autologous bone marrow transplantation. Repetto, L., Jaiprakash, M.P., Selby, P.J., Gusterson, B.A., Williams, H.J., McElwain, T.J. Hematological oncology. (1986) [Pubmed]
  31. Castleman disease in the anterior neck: the role of Ga-67 scintigraphy. Kinoshita, T., Ishii, K., Mori, Y., Naganuma, H. Clinical nuclear medicine. (1996) [Pubmed]
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