The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Dermatitis, Exfoliative

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Dermatitis, Exfoliative

 

High impact information on Dermatitis, Exfoliative

 

Chemical compound and disease context of Dermatitis, Exfoliative

 

Biological context of Dermatitis, Exfoliative

 

Anatomical context of Dermatitis, Exfoliative

 

Gene context of Dermatitis, Exfoliative

  • Keratin gene mutations can influence the filament integrity thereby causing several heritable blistering disorders of the skin such as epidermolysis bullosa, bullous icthyosiform erythroderma, etc [17].
  • In 5 patients with idiopathic erythroderma we detected T-cell clones in peripheral blood (in 1 case, associated with the presence of the same clone in the skin) and a 2-fold increase in the proportion of CD3+ CD4+ CD7- CD26- cells [18].
  • RESULTS: Mean endothelial expression in erythroderma was as follows: VCAM-1 51.4%, ICAM-1 70.1%, E-selectin 43.5%, and P-selectin 52.6% [19].
  • INTERPRETATION AND CONCLUSIONS: The presence of CD28+/CD5+/NKa-/CD4+ T cells expressing abnormally low levels of CD3, TCRalphabeta, CD4, CD7 and/or CD2 would support the diagnosis of SS in patients with erythroderma [20].
  • Blood involvement was related to the type of cutaneous T-stage, being present in 90% of patients with erythroderma (T4), 27% of those with cutaneous tumors (T3), 9% of those with generalized (T2), and 0% of those with limited skin plaques (T1) [21].
 

Analytical, diagnostic and therapeutic context of Dermatitis, Exfoliative

References

  1. Drug-induced liver injury. In vitro demonstration of hypersensitivity to both phenytoin and phenobarbital. Kahn, H.D., Faguet, G.B., Agee, J.F., Middleton, H.M. Arch. Intern. Med. (1984) [Pubmed]
  2. Cutaneous adverse reactions associated with calcium channel blockers. Stern, R., Khalsa, J.H. Arch. Intern. Med. (1989) [Pubmed]
  3. Efficacy and safety of aztreonam in the treatment of serious gram-negative bacterial infections. LeFrock, J.L., Smith, B.R., Chandrasekar, P., Rolston, K.V., Molavi, A., Kannangara, W. Arch. Intern. Med. (1987) [Pubmed]
  4. Etretinate-induced skeletal muscle damage. Hodak, E., David, M., Gadoth, N., Sandbank, M. Br. J. Dermatol. (1987) [Pubmed]
  5. An appraisal of acitretin therapy in children with inherited disorders of keratinization. Lacour, M., Mehta-Nikhar, B., Atherton, D.J., Harper, J.I. Br. J. Dermatol. (1996) [Pubmed]
  6. Toxic erythroderma due to ticlopidine. Hsi, D.H., Mock, D.J., Rocco, T.A. N. Engl. J. Med. (1999) [Pubmed]
  7. Dermatologic changes associated with interleukin 2 administration. Gaspari, A.A., Lotze, M.T., Rosenberg, S.A., Stern, J.B., Katz, S.I. JAMA (1987) [Pubmed]
  8. Chlorpropamide-induced granulomas. A probable hypersensitivity reaction in liver and bone marrow. Rigberg, L.A., Robinson, M.J., Espiritu, C.R. JAMA (1976) [Pubmed]
  9. Circulating vascular permeability factor/vascular endothelial growth factor in erythroderma. Creamer, D., Allen, M.H., Groves, R.W., Barker, J.N. Lancet (1996) [Pubmed]
  10. Association of erythrodermic cutaneous T-cell lymphoma, superantigen-positive Staphylococcus aureus, and oligoclonal T-cell receptor V beta gene expansion. Jackow, C.M., Cather, J.C., Hearne, V., Asano, A.T., Musser, J.M., Duvic, M. Blood (1997) [Pubmed]
  11. Scleromyxedema myopathy: case report and review of the literature. Helfrich, D.J., Walker, E.R., Martinez, A.J., Medsger, T.A. Arthritis Rheum. (1988) [Pubmed]
  12. Exfoliative dermatitis during cefoxitin therapy. Kannangara, D.W., Smith, B., Cohen, K. Arch. Intern. Med. (1982) [Pubmed]
  13. Exfoliative dermatitis during lithium treatment. Kuhnley, E.J., Granoff, A.L. The American journal of psychiatry. (1979) [Pubmed]
  14. Zidovudine-related erythroderma and successful desensitization: a case report. Duque, S., de la Puente, J., Rodríguez, F., Fernandez Pellón, L., Maquiera, E., Jerez, J. J. Allergy Clin. Immunol. (1996) [Pubmed]
  15. Generalized eruption with severe liver dysfunction associated with occupational exposure to trichloroethylene. Nakayama, H., Kobayashi, M., Takahashi, M., Ageishi, Y., Takano, T. Contact Derm. (1988) [Pubmed]
  16. Interleukin 4 and interferon-gamma expression of the dermal infiltrate in patients with erythroderma and mycosis fungoides. An immuno-histochemical study. Sigurdsson, V., Toonstra, J., Bihari, I.C., Bruijnzeel-Koomen, C.A., van Vloten, W.A., Thepen, T. J. Cutan. Pathol. (2000) [Pubmed]
  17. Keratins and skin disorders. Rao, K.S., Babu, K.K., Gupta, P.D. Cell Biol. Int. (1996) [Pubmed]
  18. Monoclonal T-cell dyscrasia of undetermined significance associated with recalcitrant erythroderma. Gniadecki, R., Lukowsky, A. Archives of dermatology. (2005) [Pubmed]
  19. Expression of VCAM-1, ICAM-1, E-selectin, and P-selectin on endothelium in situ in patients with erythroderma, mycosis fungoides and atopic dermatitis. Sigurdsson, V., de Vries, I.J., Toonstra, J., Bihari, I.C., Thepen, T., Bruijnzeel-Koomen, C.A., van Vloten, W.A. J. Cutan. Pathol. (2000) [Pubmed]
  20. Utility of flow cytometry immunophenotyping and DNA ploidy studies for diagnosis and characterization of blood involvement in CD4+ Sézary's syndrome. Lima, M., Almeida, J., dos Anjos Teixeira, M., Queiros, M.L., Santos, A.H., Fonseca, S., Balanzategui, A., Justica, B., Orfao, A. Haematologica (2003) [Pubmed]
  21. Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphoma. Schechter, G.P., Sausville, E.A., Fischmann, A.B., Soehnlen, F., Eddy, J., Matthews, M., Gazdar, A., Guccion, J., Munson, D., Makuch, R. Blood (1987) [Pubmed]
  22. Paraneoplastic erythroderma in a prostate cancer patient. Momm, F., Pflieger, D., Lutterbach, J. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]. (2002) [Pubmed]
  23. Localization of haptoglobin in normal human skin and some skin diseases. Li, P., Gao, X.H., Chen, H.D., Zhang, Y., Wang, Y., Wang, H., Wang, Y., Xie, Y. International journal of dermatology. (2005) [Pubmed]
 
WikiGenes - Universities