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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Splints

  • This study evaluated the effectiveness of soft splints made from polyurethane foam in reducing severe knee-flexion contractures of patients with cerebral palsy [1].
  • METHODS: Radiographs and two- or three-phase bone scintigraphs with Tc-99m MDP were obtained in three runners who had exercise-related leg pain and whose clinical symptoms suggested either stress fractures or shin splints [2].
  • The present summary and the following papers (I--VII) are submitted in partial fulfillment of the requirements for the degree of Doctor Odontologiae at the University of Bergen. 1: Growth of dental plaque on hydroxyapatite splints [3].
  • A volunteer who suffered from no dentinal hypersensitivity had modified study models prepared for constructing vacuum-formed PVC splints [4].
  • After insertion of the splints there was an immediate, approximately two-fold rise of the mean 24 h urinary cortisol excretion rate and a significant decrease of urinary volume and body weight [5].

Psychiatry related information on Splints


High impact information on Splints

  • Silver ring splints improve dexterity in patients with rheumatoid arthritis [7].
  • Typically, branched precursors and complementary linear templates ("splints") were dissolved in an equimolar ratio at a total concentration of 10(-4) M, and ligation was promoted by addition of cyanogen bromide in a pH 7.6 buffer [8].
  • Two pieces each of titanium, hydroxyapatite, and amalgam of similar size were placed in cobalt-chromium splints and kept intra-orally in each individual for 10 min, and 1, 3, 6, 24, and 72 hrs [9].
  • Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H [10].
  • We used lidocaine (2%) or nasal splints to diminish afferent airway receptor activity and measured the electromyogram (EMG) activity of the NDMs during incremental bicycle exercise in subjects who breathed nasally [11].

Biological context of Splints


Anatomical context of Splints

  • Test pieces of amalgam, casting alloys, titanium, ceramics, glass polyalkenoate cement, composite resins, unfilled resins, and bovine enamel were attached to the buccal and lingual surfaces of the upper first molars in 3 subjects using removable intraoral splints [14].
  • Silastic reinforced Marlex or Vicryl splints placed around the intact rapidly growing trachea do not significantly limit its growth [15].
  • Vectorial analysis of the equilibrium of forces transmitted to TMJ and occlusal biteplane splints [16].
  • Electromyographic investigation of subjects wearing dynamic flexor tendon repair (Kleinert) splints shows a wide variability in the amount of contraction in the flexor digitorum profundus muscle during extension of the finger [17].
  • II: Pellicle formation on hydroxyapatite splints attached to the human dentition: Morphologic confirmation of the concept of adsorption [3].

Associations of Splints with chemical compounds

  • RESULTS: Neither occlusal stabilization splints nor palatal splints had an influence on the SB outcome variables or on the sleep variables measured on a group level [6].
  • Various cooling modalities are used to apply cold to the injured area, e.g. ice packs, ice towels, ice massage, frozen gel packs, ethyl chloride and other vapocoolants, chemical reaction devices and inflatable splints using refrigerant gas [18].
  • Using methylmethacrylate to make external fixation splints [19].
  • Eight patients (nine cases) with pisotriquetral arthritis were treated by pisiform excision after they had failed to respond to splints, antiinflammatory agents, and local steroid injection [20].
  • Through 12 visits to primary and specialty care physicians over 3 years, she experienced minimal improvement with splints and moderate improvement with gabapentin [21].

Gene context of Splints

  • Increased carpal-tunnel pressure has been implicated in the pathophysiology of carpal tunnel syndrome, but it is not known whether splints that immobilize the wrist in a functional position of extension minimize carpal tunnel pressure [22].
  • Microsurgical tubal reanastomosis--the role of splints [23].
  • Alae nasi EMG was recorded in 10 normal men under the following conditions: 1) nasal breathing (all potential nasal receptors exposed), 2) oral breathing (nasal receptors not exposed), 3) nasal breathing with splints (airway deformation prevented), and 4) nasal breathing after nasal anesthesia (mucosal receptors anesthetized) [24].
  • Temporary splints to immobilize periodontally diseased teeth were made by fiber glass bonded and attached to the teeth with acid-etch technique with BIS-GMA resin [25].
  • The splints are constructed with 0.406 mm round, straight or Arch Blank preformed stainless-steel wires, with 0.559 mm standard edgewise brackets and with 0.254 mm stainless-steel or 3.05 mm elastomeric ligatures [26].

Analytical, diagnostic and therapeutic context of Splints


  1. Efficacy of soft splints in reducing severe knee-flexion contractures. Anderson, J.P., Snow, B., Dorey, F.J., Kabo, J.M. Developmental medicine and child neurology. (1988) [Pubmed]
  2. Longitudinal tibial fatigue fracture: an uncommon stress fracture with characteristic features. Pozderac, R.V. Clinical nuclear medicine. (2002) [Pubmed]
  3. Morphologic studies on dental plaque formation. Lie, T. Acta Odontol. Scand. (1979) [Pubmed]
  4. A pilot study of intraoral temperature changes. Youngson, C.C., Barclay, C.W. Clinical oral investigations. (2000) [Pubmed]
  5. Occlusal dysfunction and stress. An experimental study in macaque monkeys. Budtz-Jørgensen, E. Journal of oral rehabilitation. (1981) [Pubmed]
  6. Controlled assessment of the efficacy of occlusal stabilization splints on sleep bruxism. van der Zaag, J., Lobbezoo, F., Wicks, D.J., Visscher, C.M., Hamburger, H.L., Naeije, M. Journal of orofacial pain. (2005) [Pubmed]
  7. Silver ring splints improve dexterity in patients with rheumatoid arthritis. Zijlstra, T.R., Heijnsdijk-Rouwenhorst, L., Rasker, J.J. Arthritis Rheum. (2004) [Pubmed]
  8. Template-mediated synthesis of lariat RNA and DNA. Carriero, S., Damha, M.J. J. Org. Chem. (2003) [Pubmed]
  9. Bacterial colonization on titanium, hydroxyapatite, and amalgam surfaces in vivo. Leonhardt, A., Olsson, J., Dahlén, G. J. Dent. Res. (1995) [Pubmed]
  10. Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. Inoue, H., Hayase, Y., Iwai, S., Ohtsuka, E. FEBS Lett. (1987) [Pubmed]
  11. Control of nasal dilator muscle activities during exercise: role of nasopharyngeal afferents. Sullivan, J., Fuller, D., Fregosi, R.F. J. Appl. Physiol. (1996) [Pubmed]
  12. Comparison of nonsurgical treatment measures for de Quervain's disease of pregnancy and lactation. Avci, S., Yilmaz, C., Sayli, U. The Journal of hand surgery. (2002) [Pubmed]
  13. Comparison of range-of-motion constraints provided by prefabricated splints used in the treatment of carpal tunnel syndrome: a pilot study. Apfel, E., Johnson, M., Abrams, R. Journal of hand therapy : official journal of the American Society of Hand Therapists. (2002) [Pubmed]
  14. Transmission electron microscopy of early plaque formation on dental materials in vivo. Hannig, M. Eur. J. Oral Sci. (1999) [Pubmed]
  15. Effect of prosthetic airway splint on the growing trachea. Murphy, J.P., Filler, R.M., Muraji, T., Bahoric, A., Kent, G., Smith, C. J. Pediatr. Surg. (1983) [Pubmed]
  16. Vectorial analysis of the equilibrium of forces transmitted to TMJ and occlusal biteplane splints. dos Santos, J.D., de Rijk, W.G. Journal of oral rehabilitation. (1995) [Pubmed]
  17. Dynamic splinting following flexor tendon repair. Citron, N.D., Forster, A. Journal of hand surgery (Edinburgh, Lothian) (1987) [Pubmed]
  18. The use of cryotherapy in sports injuries. Meeusen, R., Lievens, P. Sports medicine (Auckland, N.Z.) (1986) [Pubmed]
  19. Using methylmethacrylate to make external fixation splints. Aron, J.D. The Journal of bone and joint surgery. American volume. (1976) [Pubmed]
  20. Excision of pisiform in pisotriquetral arthritis. Johnston, G.H., Tonkin, M.A. Clin. Orthop. Relat. Res. (1986) [Pubmed]
  21. Arnold-Chiari malformation with syrinx presenting as carpal tunnel syndrome: a case report. Ziadeh, M.J., Richardson, J.K. Archives of physical medicine and rehabilitation. (2004) [Pubmed]
  22. Position of the wrist associated with the lowest carpal-tunnel pressure: implications for splint design. Weiss, N.D., Gordon, L., Bloom, T., So, Y., Rempel, D.M. The Journal of bone and joint surgery. American volume. (1995) [Pubmed]
  23. Microsurgical tubal reanastomosis--the role of splints. Meldrum, D.R. Obstetrics and gynecology. (1981) [Pubmed]
  24. Mechanisms of control of alae nasi muscle activity. Mezzanotte, W.S., Tangel, D.J., White, D.P. J. Appl. Physiol. (1992) [Pubmed]
  25. Fiber glass splints. Friskopp, J., Blomlöf, L., Söder, P.O. J. Periodontol. (1979) [Pubmed]
  26. Management of dental trauma: development of a 2D data acquisition system to evaluate passivity of dental splints. Prévost, J., Nivoit, M., Granjon, Y. Medical & biological engineering & computing. (1997) [Pubmed]
  27. Pantographic records on TMJ dysfunction subjects treated with occlusal splints: a progress report. Roura, N., Clayton, J.A. The Journal of prosthetic dentistry. (1975) [Pubmed]
  28. Myofascial pain dysfunction: treatments used by ADA members. Glass, E.G., Glaros, A.G., McGlynn, F.D. Cranio : the journal of craniomandibular practice. (1993) [Pubmed]
  29. Effects of occlusal treatment and intraarticular injections on temporomandibular joint pain and dysfunction. Kopp, S., Wenneberg, B. Acta Odontol. Scand. (1981) [Pubmed]
  30. Managing bruxism and temporomandibular disorders using a centric relation occlusal device. Nassif, N.J., al-Ghamdi, K.S. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) (1999) [Pubmed]
  31. Influence of the vertical dimension in the treatment of myofascial pain-dysfunction syndrome. Manns, A., Miralles, R., Santander, H., Valdivia, J. The Journal of prosthetic dentistry. (1983) [Pubmed]
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