Disease relevance of benzene

• Re: Benzene and the dose-related incidence of hematologic neoplasms in China [1].
• Statistically significant deficits for the Benzene Subregistry population overall were found for asthma, emphysema, or chronic bronchitis; arthritis, rheumatism, or other joint disorders; hearing impairment; and speech impairment [2].
• Causal Relationship between Non-Hodgkin's Lymphoma and Exposure to Benzene and Benzene-Containing Solvents [3].
• Benzene Exposure and Multiple Myeloma: A Detailed Meta-analysis of Benzene Cohort Studies [4].
• Frequent p53 and H-ras Mutations in Benzene- and Ethylene Oxide-Induced Mammary Gland Carcinomas from B6C3F1 Mice [5].

High impact information on benzene

• Photoreaction of a 2,11-Diaza[3.3]paracyclophane Derivative: Formation of Octahedrane by Photochemical Dimerization of Benzene [6].
• Are C-H groups significant hydrogen bonding sites in anion receptors? Benzene complexes with Cl-, NO3-, and ClO4- [7].
• The benzene concentration in the work-place air ranged from 0.014-0.743 p.p.m. (geometric mean 0.557 p.p.m.). Benzene exposure was associated with significant increases in both monosomy and trisomy of chromosomes 8 and 21 [8].
• Highly Efficient Construction of Benzene Ring in Carbazoles by Palladium-Catalyzed endo-Mode Oxidative Cyclization of 3-(3'-Alkenyl)indoles [9].
• [reaction: see text] Benzene-fused cyclic sulfamates are prepared from ortho-substituted phenolic starting materials through selective C-H amination or olefin aziridination [10].

Chemical compound and disease context of benzene

• This strain was identified as Pseudomonas sp. strain S5, and was shown to degrade BTEX (Benzene, Toluene, Ethyl-Benzene, and Xylene) [11].

Biological context of benzene

• Twelve week old male birds (Gallus domesticus) were intragastrically administered technical grade samples of Benzene hexachloride (gamma-isomer: 13%) and X-factor (gamma-isomer: 16%) [a by-product obtained during separation of gamma-isomer from (BHC)] in capsules with a view of establishing oral LD50 values [12].
• The results and their analyses were summarized as follows: 1) Benzene can induce mainly chromatid-type deletions, especially gaps, suggesting that the cells in their late S-G2 stage have a higher susceptibility to chromosome breakage by benzene [13].
• Adsorption Energies, Inter-adsorbate Interactions, and the Two Binding Sites within Monolayer Benzene on Ag(111) [14].

Anatomical context of benzene

• To elucidate mechanisms involved in viral versus chemical induction of 2-5A Synthetase and PKR, MDBK cell lines were cultured either in the presence or absence of HHV6, MTBE, or Benzene, heat shock proteins and interferon-beta [15].
• We have compared the efficacy of various clearing agents such as Xylene, Benzene, Methyl salicylate and Eugenol, using 40 maxillary second premolars as experimental subjects [16].

Associations of benzene with other chemical compounds

• Analysis of urine samples for compounds such as lead, phenol, or 4,4'-methylene bis (2-chloroaniline) (MBOCA) are often adjusted for specific gravity following a recommendation in a NIOSH Benzene Criteria Document [17].
• A fluorescence enhancement phenomenon in the europium (Eu)-Ofloxacin (OF)-Sodium Dodecyl Benzene Sulfonate (SDBS) fluorescence system was observed when Gd(3+) was added [18].

Gene context of benzene

• A clear induction of 2-5A and PKR was observed when MDBK cells were exposed to HHV6, MTBE, and Benzene [15].
• Clinical features of hematopoietic malignancies and related disorders among benzene-exposed workers in China. Benzene Study Group [19].
• While in MTBE + Benzene exposed cells anti IFN-beta reduced the activity of these enzymes by 40% and anti-HSP70 by more than 90% [15].
• Classification of Risk Occupation for Benzene Exposure by Urine Trans, Trans - munconic Acid Level [20].
• Inhibition of Biogas Production by Alkyl Benzene Sulfonates (LAS) in a Screening Test for Anaerobic Biodegradability [21].

Analytical, diagnostic and therapeutic context of benzene

• An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group [22].

References