Gene Review:
HDAC5 - histone deacetylase 5
Homo sapiens
Synonyms:
Antigen NY-CO-9, FLJ90614, HD5, Histone deacetylase 5, KIAA0600, ...
- Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Vega, R.B., Harrison, B.C., Meadows, E., Roberts, C.R., Papst, P.J., Olson, E.N., McKinsey, T.A. Mol. Cell. Biol. (2004)
- Histone deacetylase 5 is not a p53 target gene, but its overexpression inhibits tumor cell growth and induces apoptosis. Huang, Y., Tan, M., Gosink, M., Wang, K.K., Sun, Y. Cancer Res. (2002)
- Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation. Watamoto, K., Towatari, M., Ozawa, Y., Miyata, Y., Okamoto, M., Abe, A., Naoe, T., Saito, H. Oncogene (2003)
- Innate immunity and colonic inflammation: enhanced expression of epithelial alpha-defensins. Wehkamp, J., Schwind, B., Herrlinger, K.R., Baxmann, S., Schmidt, K., Duchrow, M., Wohlschläger, C., Feller, A.C., Stange, E.F., Fellermann, K. Dig. Dis. Sci. (2002)
- Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. McKinsey, T.A., Zhang, C.L., Lu, J., Olson, E.N. Nature (2000)
- Dichotomy of Ca2+ in the heart: contraction versus intracellular signaling. Molkentin, J.D. J. Clin. Invest. (2006)
- An expression screen reveals modulators of class II histone deacetylase phosphorylation. Chang, S., Bezprozvannaya, S., Li, S., Olson, E.N. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes. Hook, S.S., Orian, A., Cowley, S.M., Eisenman, R.N. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein. Hoshino, M., Tagawa, K., Okuda, T., Murata, M., Oyanagi, K., Arai, N., Mizutani, T., Kanazawa, I., Wanker, E.E., Okazawa, H. J. Neurochem. (2003)
- Class II histone deacetylases: structure, function, and regulation. Bertos, N.R., Wang, A.H., Yang, X.J. Biochem. Cell Biol. (2001)
- Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells. Waltregny, D., North, B., Van Mellaert, F., de Leval, J., Verdin, E., Castronovo, V. European journal of histochemistry : EJH. (2004)
- Identification of a signal-responsive nuclear export sequence in class II histone deacetylases. McKinsey, T.A., Zhang, C.L., Olson, E.N. Mol. Cell. Biol. (2001)
- Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2. Berger, I., Bieniossek, C., Schaffitzel, C., Hassler, M., Santelli, E., Richmond, T.J. J. Biol. Chem. (2003)
- Altered HDAC5 and CREB mRNA expressions in the peripheral leukocytes of major depression. Iga, J., Ueno, S., Yamauchi, K., Numata, S., Kinouchi, S., Tayoshi-Shibuya, S., Song, H., Ohmori, T. Prog. Neuropsychopharmacol. Biol. Psychiatry (2007)
- Differential expression of human alpha- and beta-defensins mRNA in gastrointestinal epithelia. Frye, M., Bargon, J., Lembcke, B., Wagner, T.O., Gropp, R. Eur. J. Clin. Invest. (2000)
- High level expression of human epithelial beta-defensins (hBD-1, 2 and 3) in papillomavirus induced lesions. Chong, K.T., Xiang, L., Wang, X., Jun, E.L., Xi, L.F., Schweinfurth, J.M. Virol. J. (2006)
- Protein kinase D directly phosphorylates histone deacetylase 5 via a random sequential kinetic mechanism. Huynh, Q.K., McKinsey, T.A. Arch. Biochem. Biophys. (2006)
- Regulation of cardiac stress signaling by protein kinase d1. Harrison, B.C., Kim, M.S., van Rooij, E., Plato, C.F., Papst, P.J., Vega, R.B., McAnally, J.A., Richardson, J.A., Bassel-Duby, R., Olson, E.N., McKinsey, T.A. Mol. Cell. Biol. (2006)
- Myocardin induces cardiomyocyte hypertrophy. Xing, W., Zhang, T.C., Cao, D., Wang, Z., Antos, C.L., Li, S., Wang, Y., Olson, E.N., Wang, D.Z. Circ. Res. (2006)
- Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5. Zhou, X., Richon, V.M., Rifkind, R.A., Marks, P.A. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Three proteins define a class of human histone deacetylases related to yeast Hda1p. Grozinger, C.M., Hassig, C.A., Schreiber, S.L. Proc. Natl. Acad. Sci. U.S.A. (1999)
- SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains. Wu, X., Li, H., Park, E.J., Chen, J.D. J. Biol. Chem. (2001)
- Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors. Bradbury, C.A., Khanim, F.L., Hayden, R., Bunce, C.M., White, D.A., Drayson, M.T., Craddock, C., Turner, B.M. Leukemia (2005)
- Multiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibition. Castet, A., Boulahtouf, A., Versini, G., Bonnet, S., Augereau, P., Vignon, F., Khochbin, S., Jalaguier, S., Cavaillès, V. Nucleic Acids Res. (2004)
- Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization. Grozinger, C.M., Schreiber, S.L. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Chromosomal organization and localization of the human histone deacetylase 5 gene (HDAC5). Mahlknecht, U., Schnittger, S., Ottmann, O.G., Schoch, C., Mosebach, M., Hiddemann, W., Hoelzer, D. Biochim. Biophys. Acta (2000)
- Is the international prognostic score for advanced stage Hodgkin's disease applicable to early stage patients? German Hodgkin Lymphoma Study Group. Franklin, J., Paulus, U., Lieberz, D., Breuer, K., Tesch, H., Diehl, V. Ann. Oncol. (2000)