Gene Review:
Galr1 - galanin receptor 1
Mus musculus
Synonyms:
GAL1-R, GALR-1, Galanin receptor type 1, Galnr, Galnr1
Mazarati,
Lu,
Shinmei,
Badie-Mahdavi,
Bartfai,
Holmes,
Kinney,
Wrenn,
Li,
Yang,
Ma,
Vishwanath,
Saavedra,
Innerfield,
Jacoby,
Shine,
Iismaa,
Crawley,
Holmes,
Li,
Koenig,
Gold,
Stephenson,
Yang,
Dreiling,
Sullivan,
Crawley,
Wang,
He,
Maguire,
Clemmons,
Burrier,
Guzzi,
Strader,
Parker,
Bayne,
Grass,
Jacoby,
Iismaa,
Crawley,
Xu,
Wiesenfeld-Hallin,
- Hyperalgesia and increased neuropathic pain-like response in mice lacking galanin receptor 1 receptors. Blakeman, K.H., Hao, J.X., Xu, X.J., Jacoby, A.S., Shine, J., Crawley, J.N., Iismaa, T., Wiesenfeld-Hallin, Z. Neuroscience (2003)
- Critical role for GALR1 galanin receptor in galanin regulation of neuroendocrine function and seizure activity. Jacoby, A.S., Hort, Y.J., Constantinescu, G., Shine, J., Iismaa, T.P. Brain Res. Mol. Brain Res. (2002)
- Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (GalR1) knockout mice. Mazarati, A., Lu, X., Shinmei, S., Badie-Mahdavi, H., Bartfai, T. Neuroscience (2004)
- Analysis of the contribution of galanin receptors 1 and 2 to the central actions of galanin-like peptide. Krasnow, S.M., Hohmann, J.G., Gragerov, A., Clifton, D.K., Steiner, R.A. Neuroendocrinology (2004)
- Selective reduction in ventral hippocampal acetylcholine release in awake galanin-treated rats and galanin-overexpressing transgenic mice. Laplante, F., Crawley, J.N., Quirion, R. Regul. Pept. (2004)
- Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders. Ogren, S.O., Kuteeva, E., Hökfelt, T., Kehr, J. CNS drugs. (2006)
- Galanin can attenuate opiate reinforcement and withdrawal. Picciotto, M.R., Hawes, J.J., Brunzell, D.H., Zachariou, V. Neuropeptides (2005)
- Pathogenic Escherichia coli increase Cl- secretion from intestinal epithelia by upregulating galanin-1 receptor expression. Hecht, G., Marrero, J.A., Danilkovich, A., Matkowskyj, K.A., Savkovic, S.D., Koutsouris, A., Benya, R.V. J. Clin. Invest. (1999)
- Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Yoshitake, T., Wang, F.H., Kuteeva, E., Holmberg, K., Yamaguchi, M., Crawley, J.N., Steiner, R., Bartfai, T., Ogren, S.O., Hökfelt, T., Kehr, J. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze. Holmes, A., Kinney, J.W., Wrenn, C.C., Li, Q., Yang, R.J., Ma, L., Vishwanath, J., Saavedra, M.C., Innerfield, C.E., Jacoby, A.S., Shine, J., Iismaa, T.P., Crawley, J.N. Neuropsychopharmacology (2003)
- Galanin receptor 1 gene expression is regulated by cyclic AMP through a CREB-dependent mechanism. Zachariou, V., Georgescu, D., Kansal, L., Merriam, P., Picciotto, M.R. J. Neurochem. (2001)
- Genomic organization and functional characterization of the mouse GalR1 galanin receptor. Wang, S., He, C., Maguire, M.T., Clemmons, A.L., Burrier, R.E., Guzzi, M.F., Strader, C.D., Parker, E.M., Bayne, M.L. FEBS Lett. (1997)
- Flexor reflex excitability in mice lacking galanin receptor galanin-R1. Grass, S., Jacoby, A.S., Iismaa, T.P., Crawley, J.N., Xu, X.J., Wiesenfeld-Hallin, Z. Neurosci. Lett. (2003)
- Upregulation of galanin binding sites and GalR1 mRNA levels in the mouse locus coeruleus following chronic morphine treatments and precipitated morphine withdrawal. Zachariou, V., Thome, J., Parikh, K., Picciotto, M.R. Neuropsychopharmacology (2000)
- Galanin receptor-1 knockout mice exhibit spontaneous epilepsy, abnormal EEGs and altered inhibition in the hippocampus. McColl, C.D., Jacoby, A.S., Shine, J., Iismaa, T.P., Bekkers, J.M. Neuropharmacology (2006)
- Anticonvulsant activity of a nonpeptide galanin receptor agonist. Saar, K., Mazarati, A.M., Mahlapuu, R., Hallnemo, G., Soomets, U., Kilk, K., Hellberg, S., Pooga, M., Tolf, B.R., Shi, T.S., Hökfelt, T., Wasterlain, C., Bartfai, T., Langel, U. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Dextran sulfate sodium-induced murine colitis activates NF-kappaB and increases galanin-1 receptor expression. Marrero, J.A., Matkowskyj, K.A., Yung, K., Hecht, G., Benya, R.V. Am. J. Physiol. Gastrointest. Liver Physiol. (2000)
- Distribution and regulation of galanin receptor 1 messenger RNA in the forebrain of wild type and galanin-transgenic mice. Hohmann, J.G., Juréus, A., Teklemichael, D.N., Matsumoto, A.M., Clifton, D.K., Steiner, R.A. Neuroscience (2003)
- Mice over-expressing galanin have elevated heat nociceptive threshold. Blakeman, K.H., Holmberg, K., Hao, J.X., Xu, X.J., Kahl, U., Lendahl, U., Bartfai, T., Wiesenfeld-Hallin, Z., Hökfelt, T. Neuroreport (2001)
- Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2). Gottsch, M.L., Zeng, H., Hohmann, J.G., Weinshenker, D., Clifton, D.K., Steiner, R.A. Mol. Cell. Biol. (2005)
- Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice. He, B., Counts, S.E., Perez, S.E., Hohmann, J.G., Koprich, J.B., Lipton, J.W., Steiner, R.A., Crawley, J.N., Mufson, E.J. Neuroscience (2005)
- Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior. Holmes, A., Li, Q., Koenig, E.A., Gold, E., Stephenson, D., Yang, R.J., Dreiling, J., Sullivan, T., Crawley, J.N. Psychopharmacology (Berl.) (2005)
- The galanin antagonist M35 has intrinsic agonistic activity in the dorsal root ganglion. Mahoney, S.A., Hosking, R., Wynick, D. Neuroreport (2003)