Gene Review:
Nkx3-1 - NK-3 transcription factor, locus 1...
Mus musculus
Synonyms:
Bax, Homeobox protein NK-3 homolog A, Homeobox protein Nkx-3.1, NKX3.1, NKX3A, ...
Abate-Shen,
Banach-Petrosky,
Sun,
Economides,
Desai,
Gregg,
Borowsky,
Cardiff,
Shen,
Abdulkadir,
Magee,
Peters,
Kaleem,
Naughton,
Humphrey,
Milbrandt,
- Emergence of androgen independence at early stages of prostate cancer progression in nkx3.1; pten mice. Gao, H., Ouyang, X., Banach-Petrosky, W.A., Shen, M.M., Abate-Shen, C. Cancer Res. (2006)
- Vitamin d inhibits the formation of prostatic intraepithelial neoplasia in nkx3.1; pten mutant mice. Banach-Petrosky, W., Ouyang, X., Gao, H., Nader, K., Ji, Y., Suh, N., Dipaola, R.S., Abate-Shen, C. Clin. Cancer Res. (2006)
- Roles for Nkx3.1 in prostate development and cancer. Bhatia-Gaur, R., Donjacour, A.A., Sciavolino, P.J., Kim, M., Desai, N., Young, P., Norton, C.R., Gridley, T., Cardiff, R.D., Cunha, G.R., Abate-Shen, C., Shen, M.M. Genes Dev. (1999)
- Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Abdulkadir, S.A., Magee, J.A., Peters, T.J., Kaleem, Z., Naughton, C.K., Humphrey, P.A., Milbrandt, J. Mol. Cell. Biol. (2002)
- Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Kim, M.J., Cardiff, R.D., Desai, N., Banach-Petrosky, W.A., Parsons, R., Shen, M.M., Abate-Shen, C. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2. Kim, D.W., Lassar, A.B. Mol. Cell. Biol. (2003)
- Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation. Magee, J.A., Abdulkadir, S.A., Milbrandt, J. Cancer Cell (2003)
- Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Tanaka, M., Komuro, I., Inagaki, H., Jenkins, N.A., Copeland, N.G., Izumo, S. Dev. Dyn. (2000)
- Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development. Tanaka, M., Kasahara, H., Bartunkova, S., Schinke, M., Komuro, I., Inagaki, H., Lee, Y., Lyons, G.E., Izumo, S. Dev. Genet. (1998)
- Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression. Kos, L., Chiang, C., Mahon, K.A. Mech. Dev. (1998)
- Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate. Schneider, A., Brand, T., Zweigerdt, R., Arnold, H. Mech. Dev. (2000)
- Expression of an Nkx3.1-CRE gene using ROSA26 reporter mice. Stanfel, M.N., Moses, K.A., Carson, J.A., Zimmer, D.B., Demayo, F., Schwartz, R.J., Zimmer, W.E. Genesis (2006)
- Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Abate-Shen, C., Banach-Petrosky, W.A., Sun, X., Economides, K.D., Desai, N., Gregg, J.P., Borowsky, A.D., Cardiff, R.D., Shen, M.M. Cancer Res. (2003)
- NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity. Bowen, C., Stuart, A., Ju, J.H., Tuan, J., Blonder, J., Conrads, T.P., Veenstra, T.D., Gelmann, E.P. Cancer Res. (2007)
- Tissue-specific expression of murine Nkx3.1 in the male urogenital system. Sciavolino, P.J., Abrams, E.W., Yang, L., Austenberg, L.P., Shen, M.M., Abate-Shen, C. Dev. Dyn. (1997)
- Transcription factors Nkx3.1 and Nkx3.2 (Bapx1) play an overlapping role in sclerotomal development of the mouse. Herbrand, H., Pabst, O., Hill, R., Arnold, H.H. Mech. Dev. (2002)
- Interaction of Nkx3.1 and p27kip1 in prostate tumor initiation. Gary, B., Azuero, R., Mohanty, G.S., Bell, W.C., Eltoum, I.E., Abdulkadir, S.A. Am. J. Pathol. (2004)
- Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Kim, M.J., Bhatia-Gaur, R., Banach-Petrosky, W.A., Desai, N., Wang, Y., Hayward, S.W., Cunha, G.R., Cardiff, R.D., Shen, M.M., Abate-Shen, C. Cancer Res. (2002)