Gene Review:
Nrl - neural retina leucine zipper gene
Mus musculus
Synonyms:
AW492574, D14H14S46E, NRL, Neural retina-specific leucine zipper protein
- Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl. Yoshida, S., Mears, A.J., Friedman, J.S., Carter, T., He, S., Oh, E., Jing, Y., Farjo, R., Fleury, G., Barlow, C., Hero, A.O., Swaroop, A. Hum. Mol. Genet. (2004)
- Retinoic Acid Regulates the Expression of Photoreceptor Transcription Factor NRL. Khanna, H., Akimoto, M., Siffroi-Fernandez, S., Friedman, J.S., Hicks, D., Swaroop, A. J. Biol. Chem. (2006)
- Fractionated dose of 35-MEV fast neutrons and hypoxic tumor cell survival curve. U, R., Evans, J.C., Cavanaugh, P.J., Abramson, N., Thompson, T.T., Wheless, D.M. Cancer (1975)
- Nrl is required for rod photoreceptor development. Mears, A.J., Kondo, M., Swain, P.K., Takada, Y., Bush, R.A., Saunders, T.L., Sieving, P.A., Swaroop, A. Nat. Genet. (2001)
- Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity. Pittler, S.J., Zhang, Y., Chen, S., Mears, A.J., Zack, D.J., Ren, Z., Swain, P.K., Yao, S., Swaroop, A., White, J.B. J. Biol. Chem. (2004)
- GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina. Zhu, X., Brown, B., Li, A., Mears, A.J., Swaroop, A., Craft, C.M. J. Neurosci. (2003)
- The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression. Rehemtulla, A., Warwar, R., Kumar, R., Ji, X., Zack, D.J., Swaroop, A. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Expression of the bZIP transcription factor gene Nrl in the developing nervous system. Liu, Q., Ji, X., Breitman, M.L., Hitchcock, P.F., Swaroop, A. Oncogene (1996)
- Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors. Akimoto, M., Cheng, H., Zhu, D., Brzezinski, J.A., Khanna, R., Filippova, E., Oh, E.C., Jing, Y., Linares, J.L., Brooks, M., Zareparsi, S., Mears, A.J., Hero, A., Glaser, T., Swaroop, A. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Daniele, L.L., Lillo, C., Lyubarsky, A.L., Nikonov, S.S., Philp, N., Mears, A.J., Swaroop, A., Williams, D.S., Pugh, E.N. Invest. Ophthalmol. Vis. Sci. (2005)
- RPE65 Is Essential for the Function of Cone Photoreceptors in NRL-Deficient Mice. Wenzel, A., von Lintig, J., Oberhauser, V., Tanimoto, N., Grimm, C., Seeliger, M.W. Invest. Ophthalmol. Vis. Sci. (2007)
- Altered expression of genes of the Bmp/Smad and Wnt/calcium signaling pathways in the cone-only Nrl-/- mouse retina, revealed by gene profiling using custom cDNA microarrays. Yu, J., He, S., Friedman, J.S., Akimoto, M., Ghosh, D., Mears, A.J., Hicks, D., Swaroop, A. J. Biol. Chem. (2004)
- The maf proto-oncogene stimulates transcription from multiple sites in a promoter that directs Purkinje neuron-specific gene expression. Kurschner, C., Morgan, J.I. Mol. Cell. Biol. (1995)
- Lens-specific gene recruitment of zeta-crystallin through Pax6, Nrl-Maf, and brain suppressor sites. Sharon-Friling, R., Richardson, J., Sperbeck, S., Lee, D., Rauchman, M., Maas, R., Swaroop, A., Wistow, G. Mol. Cell. Biol. (1998)
- FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro. Mali, R.S., Zhang, X., Hoerauf, W., Doyle, D., Devitt, J., Loffreda-Wren, J., Mitton, K.P. Exp. Eye Res. (2007)