Gene Review:
NRL - neural retina leucine zipper
Homo sapiens
Synonyms:
D14S46E, NRL-MAF, Neural retina-specific leucine zipper protein, RP27
- Recessive NRL mutations in patients with clumped pigmentary retinal degeneration and relative preservation of blue cone function. Nishiguchi, K.M., Friedman, J.S., Sandberg, M.A., Swaroop, A., Berson, E.L., Dryja, T.P. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Neural retina-specific leucine zipper gene NRL (D14S46E) maps to human chromosome 14q11.1-q11.2. Yang-Feng, T.L., Swaroop, A. Genomics (1992)
- Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. Acar, C., Mears, A.J., Yashar, B.M., Maheshwary, A.S., Andreasson, S., Baldi, A., Sieving, P.A., Iannaccone, A., Musarella, M.A., Jacobson, S.G., Swaroop, A. Mol. Vis. (2003)
- Retinoic Acid Regulates the Expression of Photoreceptor Transcription Factor NRL. Khanna, H., Akimoto, M., Siffroi-Fernandez, S., Friedman, J.S., Hicks, D., Swaroop, A. J. Biol. Chem. (2006)
- Heterogeneous expression of the lipocalin NGAL in primary breast cancers. Stoesz, S.P., Friedl, A., Haag, J.D., Lindstrom, M.J., Clark, G.M., Gould, M.N. Int. J. Cancer (1998)
- A mutation in NRL is associated with autosomal dominant retinitis pigmentosa. Bessant, D.A., Payne, A.M., Mitton, K.P., Wang, Q.L., Swain, P.K., Plant, C., Bird, A.C., Zack, D.J., Swaroop, A., Bhattacharya, S.S. Nat. Genet. (1999)
- From the Cover: Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL. Oh, E.C., Khan, N., Novelli, E., Khanna, H., Strettoi, E., Swaroop, A. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Natural rubber latex hypersensitivity: incidence and prevalence of type I allergy in the dental professional. Hamann, C.P., Turjanmaa, K., Rietschel, R., Siew, C., Owensby, D., Gruninger, S.E., Sullivan, K.M. Journal of the American Dental Association (1939) (1998)
- I1-imidazoline receptors: an update. Bousquet, P., Dontenwill, M., Greney, H., Feldman, J. Journal of hypertension. Supplement : official journal of the International Society of Hypertension. (1998)
- Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function. Swaroop, A., Wang, Q.L., Wu, W., Cook, J., Coats, C., Xu, S., Chen, S., Zack, D.J., Sieving, P.A. Hum. Mol. Genet. (1999)
- Functional domains of the cone-rod homeobox (CRX) transcription factor. Chau, K.Y., Chen, S., Zack, D.J., Ono, S.J. J. Biol. Chem. (2000)
- Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors. Swain, P.K., Hicks, D., Mears, A.J., Apel, I.J., Smith, J.E., John, S.K., Hendrickson, A., Milam, A.H., Swaroop, A. J. Biol. Chem. (2001)
- Mutation analysis of NR2E3 and NRL genes in Enhanced S Cone Syndrome. Wright, A.F., Reddick, A.C., Schwartz, S.B., Ferguson, J.S., Aleman, T.S., Kellner, U., Jurklies, B., Schuster, A., Zrenner, E., Wissinger, B., Lennon, A., Shu, X., Cideciyan, A.V., Stone, E.M., Jacobson, S.G., Swaroop, A. Hum. Mutat. (2004)
- Human bZIP transcription factor gene NRL: structure, genomic sequence, and fine linkage mapping at 14q11.2 and negative mutation analysis in patients with retinal degeneration. Farjo, Q., Jackson, A., Pieke-Dahl, S., Scott, K., Kimberling, W.J., Sieving, P.A., Richards, J.E., Swaroop, A. Genomics (1997)
- FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro. Mali, R.S., Zhang, X., Hoerauf, W., Doyle, D., Devitt, J., Loffreda-Wren, J., Mitton, K.P. Exp. Eye Res. (2007)
- Expression of NRL/NGAL (neu-related lipocalin/neutrophil gelatinase-associated lipocalin) during mammalian embryonic development and in inflammation. Zerega, B., Cermelli, S., Michelis, B., Cancedda, R., Cancedda, F.D. Eur. J. Cell Biol. (2000)
- The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation. Mitton, K.P., Swain, P.K., Chen, S., Xu, S., Zack, D.J., Swaroop, A. J. Biol. Chem. (2000)
- Production of Hev b5 as a fluorescent biotin-binding tripartite fusion protein in insect cells. Nordlund, H.R., Laitinen, O.H., Uotila, S.T., Kulmala, M., Kalkkinen, N., Kulomaa, M.S. Biochem. Biophys. Res. Commun. (2005)
- Binding of [3H]2-(2-benzofuranyl)-2-imidazoline (BFI) to human brain: potentiation by tranylcypromine. Wiest, S.A., Steinberg, M.I. Life Sci. (1997)
- Cross-reactivity between gutta-percha and natural rubber latex: assumptions vs. reality. Hamann, C., Rodgers, P.A., Alenius, H., Halsey, J.F., Sullivan, K. Journal of the American Dental Association (1939) (2002)
- Expression of photoreceptor-specific nuclear receptor NR2E3 in rod photoreceptors of fetal human retina. Bumsted O'Brien, K.M., Cheng, H., Jiang, Y., Schulte, D., Swaroop, A., Hendrickson, A.E. Invest. Ophthalmol. Vis. Sci. (2004)
- The minimal transactivation domain of the basic motif-leucine zipper transcription factor NRL interacts with TATA-binding protein. Friedman, J.S., Khanna, H., Swain, P.K., Denicola, R., Cheng, H., Mitton, K.P., Weber, C.H., Hicks, D., Swaroop, A. J. Biol. Chem. (2004)
- Shared mutations in NR2E3 in enhanced S-cone syndrome, Goldmann-Favre syndrome, and many cases of clumped pigmentary retinal degeneration. Sharon, D., Sandberg, M.A., Caruso, R.C., Berson, E.L., Dryja, T.P. Arch. Ophthalmol. (2003)
- NRL S50T mutation and the importance of 'founder effects' in inherited retinal dystrophies. Bessant, D.A., Payne, A.M., Plant, C., Bird, A.C., Swaroop, A., Bhattacharya, S.S. Eur. J. Hum. Genet. (2000)
- Indirect competitive immunoassay for detection of aflatoxin B(1) in corn and nut products using the array biosensor. Sapsford, K.E., Taitt, C.R., Fertig, S., Moore, M.H., Lassman, M.E., Maragos, C.M., Shriver-Lake, L.C. Biosensors & bioelectronics. (2006)