Gene Review:
Pml - promyelocytic leukemia
Mus musculus
Synonyms:
1200009E24Rik, AI661194, Protein PML, Trim19
- Role of promyelocytic leukemia (PML) protein in tumor suppression. Rego, E.M., Wang, Z.G., Peruzzi, D., He, L.Z., Cordon-Cardo, C., Pandolfi, P.P. J. Exp. Med. (2001)
- Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice. He, L.Z., Tribioli, C., Rivi, R., Peruzzi, D., Pelicci, P.G., Soares, V., Cattoretti, G., Pandolfi, P.P. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Pro-proliferative function of the long isoform of PML-RARalpha involved in acute promyelocytic leukemia. Tussié-Luna, M.I., Rozo, L., Roy, A.L. Oncogene (2006)
- Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice. Zimonjic, D.B., Pollock, J.L., Westervelt, P., Popescu, N.C., Ley, T.J. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Nuclear localization but not PML protein is required for incorporation of the papillomavirus minor capsid protein L2 into virus-like particles. Becker, K.A., Florin, L., Sapp, C., Maul, G.G., Sapp, M. J. Virol. (2004)
- A CK2-dependent mechanism for degradation of the PML tumor suppressor. Scaglioni, P.P., Yung, T.M., Cai, L.F., Erdjument-Bromage, H., Kaufman, A.J., Singh, B., Teruya-Feldstein, J., Tempst, P., Pandolfi, P.P. Cell (2006)
- PML is essential for multiple apoptotic pathways. Wang, Z.G., Ruggero, D., Ronchetti, S., Zhong, S., Gaboli, M., Rivi, R., Pandolfi, P.P. Nat. Genet. (1998)
- Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation. Lallemand-Breitenbach, V., Zhu, J., Puvion, F., Koken, M., Honoré, N., Doubeikovsky, A., Duprez, E., Pandolfi, P.P., Puvion, E., Freemont, P., de Thé, H. J. Exp. Med. (2001)
- Mouse models of acute promyelocytic leukemia. Pollock, J.L., Westervelt, P., Walter, M.J., Lane, A.A., Ley, T.J. Curr. Opin. Hematol. (2001)
- Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. Ivanov, V.N., Hei, T.K. Exp. Cell Res. (2006)
- The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage. Salomoni, P., Bernardi, R., Bergmann, S., Changou, A., Tuttle, S., Pandolfi, P.P. Blood (2005)
- Transgenic expression of PML/RARalpha impairs myelopoiesis. Early, E., Moore, M.A., Kakizuka, A., Nason-Burchenal, K., Martin, P., Evans, R.M., Dmitrovsky, E. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein. Ferrucci, P.F., Grignani, F., Pearson, M., Fagioli, M., Nicoletti, I., Pelicci, P.G. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Sumoylation of Daxx regulates IFN-induced growth suppression of B lymphocytes and the hormone receptor-mediated transactivation. Muromoto, R., Ishida, M., Sugiyama, K., Sekine, Y., Oritani, K., Shimoda, K., Matsuda, T. J. Immunol. (2006)
- Cloning of the murine homolog of the leukemia-associated PML gene. Goddard, A.D., Yuan, J.Q., Fairbairn, L., Dexter, M., Borrow, J., Kozak, C., Solomon, E. Mamm. Genome (1995)
- Adaptive immunity cooperates with liposomal all-trans-retinoic acid (ATRA) to facilitate long-term molecular remissions in mice with acute promyelocytic leukemia. Westervelt, P., Pollock, J.L., Oldfather, K.M., Walter, M.J., Ma, M.K., Williams, A., DiPersio, J.F., Ley, T.J. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid. Ponzanelli, I., Giannì, M., Giavazzi, R., Garofalo, A., Nicoletti, I., Reichert, U., Erba, E., Rambaldi, A., Terao, M., Garattini, E. Blood (2000)
- Promyelocytic leukemia zinc finger protein localizes to the cochlear outer hair cells and interacts with prestin, the outer hair cell motor protein. Nagy, I., Bodmer, M., Schmid, S., Bodmer, D. Hear. Res. (2005)
- Characterization of two novel nuclear BTB/POZ domain zinc finger isoforms. Association with differentiation of hippocampal neurons, cerebellar granule cells, and macroglia. Mitchelmore, C., Kjaerulff, K.M., Pedersen, H.C., Nielsen, J.V., Rasmussen, T.E., Fisker, M.F., Finsen, B., Pedersen, K.M., Jensen, N.A. J. Biol. Chem. (2002)
- Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX. Ishov, A.M., Vladimirova, O.V., Maul, G.G. J. Cell. Sci. (2004)
- Role of SUMO-1-modified PML in nuclear body formation. Zhong, S., Müller, S., Ronchetti, S., Freemont, P.S., Dejean, A., Pandolfi, P.P. Blood (2000)
- Mouse cytomegalovirus immediate-early protein 1 binds with host cell repressors to relieve suppressive effects on viral transcription and replication during lytic infection. Tang, Q., Maul, G.G. J. Virol. (2003)
- Identification of a tumour suppressor network opposing nuclear Akt function. Trotman, L.C., Alimonti, A., Scaglioni, P.P., Koutcher, J.A., Cordon-Cardo, C., Pandolfi, P.P. Nature (2006)
- The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1. Lalioti, V.S., Vergarajauregui, S., Pulido, D., Sandoval, I.V. J. Biol. Chem. (2002)
- Mouse models of acute promyelocytic leukemia. Kogan, S.C. Curr. Top. Microbiol. Immunol. (2007)