Gene Review:
Slc10a2 - solute carrier family 10, member 2
Mus musculus
Synonyms:
ASBT, Apical sodium-dependent bile acid transporter, IBAT, ISBT, Ileal Na(+)/bile acid cotransporter, ...
Bijvelds,
Jorna,
Verkade,
Bot,
Hofmann,
Agellon,
Sinaasappel,
de Jonge,
Ballatori,
Christian,
Lee,
Dawson,
Soroka,
Boyer,
Madejczyk,
Li,
Saeki,
Kuroda,
Matsumoto,
Kanamoto,
Iwami,
Stelzner,
Somasundaram,
Lee,
Kuver,
Saeki,
Matoba,
Furukawa,
Kirifuji,
Kanamoto,
Iwami,
Dawson,
Haywood,
Craddock,
Wilson,
Tietjen,
Kluckman,
Maeda,
Parks,
Dawson,
Hubbert,
Haywood,
Craddock,
Zerangue,
Christian,
Ballatori,
Lyons,
Korstanje,
Li,
Sheehan,
Walsh,
Rollins,
Carey,
Paigen,
Churchill,
- Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. Dawson, P.A., Haywood, J., Craddock, A.L., Wilson, M., Tietjen, M., Kluckman, K., Maeda, N., Parks, J.S. J. Biol. Chem. (2003)
- Ileal mucosal bile acid absorption is increased in Cftr knockout mice. Stelzner, M., Somasundaram, S., Lee, S.P., Kuver, R. BMC gastroenterology [electronic resource]. (2001)
- Inhibition of ileal bile acid transport and reduced atherosclerosis in apoE-/- mice by SC-435. Bhat, B.G., Rapp, S.R., Beaudry, J.A., Napawan, N., Butteiger, D.N., Hall, K.A., Null, C.L., Luo, Y., Keller, B.T. J. Lipid Res. (2003)
- Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Voss-Andreae, A., Murphy, J.G., Ellacott, K.L., Stuart, R.C., Nillni, E.A., Cone, R.D., Fan, W. Endocrinology (2007)
- Depressed expression of adipocyte beta-adrenergic receptors is a common feature of congenital and diet-induced obesity in rodents. Collins, S., Daniel, K.W., Rohlfs, E.M. Int. J. Obes. Relat. Metab. Disord. (1999)
- c-Fos is a critical mediator of inflammatory-mediated repression of the apical sodium-dependent bile acid transporter. Neimark, E., Chen, F., Li, X., Magid, M.S., Alasio, T.M., Frankenberg, T., Sinha, J., Dawson, P.A., Shneider, B.L. Gastroenterology (2006)
- CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Wagner, M., Halilbasic, E., Marschall, H.U., Zollner, G., Fickert, P., Langner, C., Zatloukal, K., Denk, H., Trauner, M. Hepatology (2005)
- OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Ballatori, N., Christian, W.V., Lee, J.Y., Dawson, P.A., Soroka, C.J., Boyer, J.L., Madejczyk, M.S., Li, N. Hepatology (2005)
- The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. Dawson, P.A., Hubbert, M., Haywood, J., Craddock, A.L., Zerangue, N., Christian, W.V., Ballatori, N. J. Biol. Chem. (2005)
- Localization of the ileal sodium-bile salt cotransporter gene (Slc10a2) to mouse chromosome 8. Lammert, F., Paigen, B., Carey, M.C. Mamm. Genome (1998)
- Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM. Lyons, M.A., Korstanje, R., Li, R., Sheehan, S.M., Walsh, K.A., Rollins, J.A., Carey, M.C., Paigen, B., Churchill, G.A. Mamm. Genome (2005)
- Coordinate regulation of bile acid biosynthetic and recovery pathways. Torchia, E.C., Cheema, S.K., Agellon, L.B. Biochem. Biophys. Res. Commun. (1996)
- Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter. Saeki, T., Matoba, K., Furukawa, H., Kirifuji, K., Kanamoto, R., Iwami, K. J. Biochem. (1999)
- Inhibition of the intestinal absorption of bile acids using cationic derivatives: Mechanism and repercussions. Vicens, M., Macias, R.I., Briz, O., Rodriguez, A., El-Mir, M.Y., Medarde, M., Marin, J.J. Biochem. Pharmacol. (2007)
- Orthotopic transplantation of intestinal mucosal organoids in rodents. Avansino, J.R., Chen, D.C., Hoagland, V.D., Woolman, J.D., Stelzner, M. Surgery (2006)
- Activation of CFTR by ASBT-mediated bile salt absorption. Bijvelds, M.J., Jorna, H., Verkade, H.J., Bot, A.G., Hofmann, F., Agellon, L.B., Sinaasappel, M., de Jonge, H.R. Am. J. Physiol. Gastrointest. Liver Physiol. (2005)
- Effects of Cys mutation on taurocholic acid transport by mouse ileal and hepatic sodium-dependent bile acid transporters. Saeki, T., Kuroda, T., Matsumoto, M., Kanamoto, R., Iwami, K. Biosci. Biotechnol. Biochem. (2002)
- Responses of sympathetic nerves innervating blood vessels in interscapular, brown adipose tissue and skin during cold stimulation in anesthetized C57BL/6J mice. Engel, B.T., Sato, A., Sato, Y. Jpn. J. Physiol. (1992)
- Ontogenetic development and spatial distribution of the ileal apical sodium-dependent bile acid transporter and the ileal lipid-binding protein in apoE knockout and C57BL/6 mice. Håkansson, P., Andersson, I., Nyström, S., Löfgren, L., Amrot, L.F., Li, H. Scand. J. Gastroenterol. (2002)
- Adrenalectomy in genetically obese ob/ob and db/db mice increases the proton conductance pathway. Shargill, N.S., Lupien, J.R., Bray, G.A. Horm. Metab. Res. (1989)
- Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage. Tsuboi, K., Tazuma, S., Nishioka, T., Chayama, K. J. Gastroenterol. (2004)