Gene Review:
KCNJ6 - potassium channel, inwardly rectifying...
Homo sapiens
Synonyms:
BIR1, G protein-activated inward rectifier potassium channel 2, GIRK-2, GIRK2, Inward rectifier K(+) channel Kir3.2, ...
Saccone,
Hinrichs,
Saccone,
Chase,
Konvicka,
Madden,
Breslau,
Johnson,
Hatsukami,
Pomerleau,
Swan,
Goate,
Rutter,
Bertelsen,
Fox,
Fugman,
Martin,
Montgomery,
Wang,
Ballinger,
Rice,
Bierut,
Lewohl,
Wilson,
Mayfield,
Brozowski,
Morrisett,
Harris,
Plummer,
Dhar,
Cekanova,
Schuller,
Plummer,
Yu,
Cakir,
Schuller,
Kostrouchova,
Kostrouch,
Saudek,
Piatigorsky,
Rall,
- Mutation analysis of the inwardly rectifying K(+) channels KCNJ6 (GIRK2) and KCNJ3 (GIRK1) in juvenile myoclonic epilepsy. Hallmann, K., Durner, M., Sander, T., Steinlein, O.K. Am. J. Med. Genet. (2000)
- Suggestive evidence for association of two potassium channel genes with different idiopathic generalised epilepsy syndromes. Chioza, B., Osei-Lah, A., Wilkie, H., Nashef, L., McCormick, D., Asherson, P., Makoff, A.J. Epilepsy Res. (2002)
- Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines. Plummer, H.K., Dhar, M.S., Cekanova, M., Schuller, H.M. BMC Cancer (2005)
- Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines. Plummer, H.K., Yu, Q., Cakir, Y., Schuller, H.M. BMC Cancer (2004)
- The human homologue of the weaver mouse gene in familial and sporadic Parkinson's disease. Bandmann, O., Davis, M.B., Marsden, C.D., Wood, N.W. Neuroscience (1996)
- Chromosome 21 KIR channels in brain development. Thiery, E., Thomas, S., Vacher, S., Delezoide, A.L., Delabar, J.M., Créau, N. J. Neural Transm. Suppl. (2003)
- The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone. Speliotes, E.K., Uren, A., Vaux, D., Horvitz, H.R. Mol. Cell (2000)
- G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action. Lewohl, J.M., Wilson, W.R., Mayfield, R.D., Brozowski, S.J., Morrisett, R.A., Harris, R.A. Nat. Neurosci. (1999)
- K+ channel selectivity depends on kinetic as well as thermodynamic factors. Grabe, M., Bichet, D., Qian, X., Jan, Y.N., Jan, L.Y. Proc. Natl. Acad. Sci. U.S.A. (2006)
- BIR-1, a Caenorhabditis elegans homologue of Survivin, regulates transcription and development. Kostrouchova, M., Kostrouch, Z., Saudek, V., Piatigorsky, J., Rall, J.E. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Hypothermic responses to 8-OH-DPAT in the Ts65Dn mouse model of Down syndrome. Stasko, M.R., Scott-McKean, J.J., Costa, A.C. Neuroreport (2006)
- Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM. Tsaur, M.L., Menzel, S., Lai, F.P., Espinosa, R., Concannon, P., Spielman, R.S., Hanis, C.L., Cox, N.J., Le Beau, M.M., German, M.S. Diabetes (1995)
- betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation. Finley, M., Arrabit, C., Fowler, C., Suen, K.F., Slesinger, P.A. J. Physiol. (Lond.) (2004)
- Controlling potassium channel activities: Interplay between the membrane and intracellular factors. Yi, B.A., Minor, D.L., Lin, Y.F., Jan, Y.N., Jan, L.Y. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Interaction of G protein beta subunit with inward rectifier K(+) channel Kir3. Zhao, Q., Kawano, T., Nakata, H., Nakajima, Y., Nakajima, S., Kozasa, T. Mol. Pharmacol. (2003)
- Human dopamine D3 and D2L receptors couple to inward rectifier potassium channels in mammalian cell lines. Kuzhikandathil, E.V., Yu, W., Oxford, G.S. Mol. Cell. Neurosci. (1998)
- Kir3.1/3.2 encodes an I(KACh)-like current in gastrointestinal myocytes. Bradley, K.K., Hatton, W.J., Mason, H.S., Walker, R.L., Flynn, E.R., Kenyon, J.L., Horowitz, B. Am. J. Physiol. Gastrointest. Liver Physiol. (2000)
- Distinct Populations of Spinal Cord Lamina II Interneurons Expressing G-Protein-Gated Potassium Channels. Marker, C.L., Luj??n, R., Col??n, J., Wickman, K. J. Neurosci. (2006)
- A glutamate residue at the C terminus regulates activity of inward rectifier K+ channels: implication for Andersen's syndrome. Chen, L., Kawano, T., Bajic, S., Kaziro, Y., Itoh, H., Art, J.J., Nakajima, Y., Nakajima, S. Proc. Natl. Acad. Sci. U.S.A. (2002)
- A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating. Guo, Y., Waldron, G.J., Murrell-Lagnado, R. J. Biol. Chem. (2002)
- Dominant-negative mutants identify a role for GIRK channels in D3 dopamine receptor-mediated regulation of spontaneous secretory activity. Kuzhikandathil, E.V., Oxford, G.S. J. Gen. Physiol. (2000)
- Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels. Ho, I.H., Murrell-Lagnado, R.D. J. Physiol. (Lond.) (1999)
- Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity. Ulens, C., Van Boven, M., Daenens, P., Tytgat, J. J. Pharmacol. Exp. Ther. (2000)
- Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex. Clancy, S.M., Fowler, C.E., Finley, M., Suen, K.F., Arrabit, C., Berton, F., Kosaza, T., Casey, P.J., Slesinger, P.A. Mol. Cell. Neurosci. (2005)
- Signal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channel. Koike-Tani, M., Collins, J.M., Kawano, T., Zhao, P., Zhao, Q., Kozasa, T., Nakajima, S., Nakajima, Y. J. Physiol. (Lond.) (2005)
- Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit. Chan, K.W., Sui, J.L., Vivaudou, M., Logothetis, D.E. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Saccone, S.F., Hinrichs, A.L., Saccone, N.L., Chase, G.A., Konvicka, K., Madden, P.A., Breslau, N., Johnson, E.O., Hatsukami, D., Pomerleau, O., Swan, G.E., Goate, A.M., Rutter, J., Bertelsen, S., Fox, L., Fugman, D., Martin, N.G., Montgomery, G.W., Wang, J.C., Ballinger, D.G., Rice, J.P., Bierut, L.J. Hum. Mol. Genet. (2007)
- Serine 329 of the mu-opioid receptor interacts differently with agonists. Pil, J., Tytgat, J. J. Pharmacol. Exp. Ther. (2003)