Chemical Compound Review:
sulfanylsulfonylmethane sulfanylsulfonylmethane
Synonyms:
- Cysteine-scanning mutagenesis and thiol modification of the Rickettsia prowazekii ATP/ADP translocase: characterization of TMs IV-VII and IX-XII and their accessibility to the aqueous translocation pathway. Audia, J.P., Roberts, R.A., Winkler, H.H. Biochemistry (2006)
- Two pore residues mediate acidosis-induced enhancement of C-type inactivation of the Kv1.4 K(+) channel. Claydon, T.W., Boyett, M.R., Sivaprasadarao, A., Orchard, C.H. Am. J. Physiol., Cell Physiol. (2002)
- Enhanced replication of herpes simplex virus type 1 in human cells. Miller, C.S., Smith, K.O. J. Dent. Res. (1991)
- Synthesis and preliminary antimicrobial screening of two thiosulfonates. Small, L.D. Journal of pharmaceutical sciences. (1976)
- Sulfhydryl groups are involved in the binding of agonists and antagonists to the human mineralocorticoid receptor. Souque, A., Fagart, J., Couette, B., Rafestin-Oblin, M.E. J. Steroid Biochem. Mol. Biol. (1996)
- S3b amino acid residues do not shuttle across the bilayer in voltage-dependent Shaker K+ channels. Gonzalez, C., Morera, F.J., Rosenmann, E., Alvarez, O., Latorre, R. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method. Wilson, G., Karlin, A. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Conformational changes couple Na+ and glucose transport. Loo, D.D., Hirayama, B.A., Gallardo, E.M., Lam, J.T., Turk, E., Wright, E.M. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Influence of Agonists and Antagonists on the Segmental Motion of Residues near the Agonist Binding Pocket of the Acetylcholine-binding Protein. Hibbs, R.E., Radic, Z., Taylor, P., Johnson, D.A. J. Biol. Chem. (2006)
- A C-terminal lysine that controls human P2X4 receptor desensitization. Fountain, S.J., North, R.A. J. Biol. Chem. (2006)
- Substituted cysteine accessibility of the third transmembrane domain of the creatine transporter: defining a transport pathway. Dodd, J.R., Christie, D.L. J. Biol. Chem. (2005)
- Mutagenesis and derivatization of human vesicle monoamine transporter 2 (VMAT2) cysteines identifies transporter domains involved in tetrabenazine binding and substrate transport. Thiriot, D.S., Ruoho, A.E. J. Biol. Chem. (2001)
- Replacement of Ala-166 with cysteine in the high affinity rabbit sodium/glucose transporter alters transport kinetics and allows methanethiosulfonate ethylamine to inhibit transporter function. Lo, B., Silverman, M. J. Biol. Chem. (1998)
- Substrate-induced conformational changes of extracellular loop 1 in the glycine transporter GLYT2. López-Corcuera, B., Núñez, E., Martínez-Maza, R., Geerlings, A., Aragón, C. J. Biol. Chem. (2001)
- Permanent activation of the human P-glycoprotein by covalent modification of a residue in the drug-binding site. Loo, T.W., Bartlett, M.C., Clarke, D.M. J. Biol. Chem. (2003)
- Cyclic nucleotide-gated channels. Pore topology studied through the accessibility of reporter cysteines. Becchetti, A., Gamel, K., Torre, V. J. Gen. Physiol. (1999)
- Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives. Huynh, P.D., Cui, C., Zhan, H., Oh, K.J., Collier, R.J., Finkelstein, A. J. Gen. Physiol. (1997)
- Steroidal affinity labels of the estrogen receptor. 2. 17 alpha-[(Haloacetamido)alkyl]estradiols. el Garrouj, D., Aliau, S., Aumelas, A., Borgna, J.L. J. Med. Chem. (1995)
- Selected cysteine residues in transmembrane domains of mu-opioid receptor are critical for effects of sulfhydryl reagents. Deng, H.B., Guang, W., Wang, J.B. J. Pharmacol. Exp. Ther. (2000)
- Sodium (2-sulfonatoethyl) methanethiosulfonate prevents S-nitroso-L-cysteine activation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caeca. Lang, R.J., Harvey, J.R., Mulholland, E.L. Br. J. Pharmacol. (2003)
- Alternating access and a pore-loop structure in the Na+-citrate transporter CitS of Klebsiella pneumoniae. Sobczak, I., Lolkema, J.S. J. Biol. Chem. (2004)
- Allosteric regulation of pyruvate kinase M2 isozyme involves a cysteine residue in the intersubunit contact. Ikeda, Y., Noguchi, T. J. Biol. Chem. (1998)
- Different residues in the GABA(A) receptor alpha 1T60-alpha 1K70 region mediate GABA and SR-95531 actions. Holden, J.H., Czajkowski, C. J. Biol. Chem. (2002)
- GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions. Boileau, A.J., Newell, J.G., Czajkowski, C. J. Biol. Chem. (2002)
- Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein. Loo, T.W., Clarke, D.M. J. Biol. Chem. (2002)
- Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods. Hou, Z., Stapels, S.E., Haska, C.L., Matherly, L.H. J. Biol. Chem. (2005)
- Membrane topology of system xc- light subunit reveals a re-entrant loop with substrate-restricted accessibility. Gasol, E., Jiménez-Vidal, M., Chillarón, J., Zorzano, A., Palacín, M. J. Biol. Chem. (2004)
- Chemical modification of the RTEM-1 thiol beta-lactamase by thiol-selective reagents: evidence for activation of the primary nucleophile of the beta-lactamase active site by adjacent functional groups. Knap, A.K., Pratt, R.F. Proteins (1989)
- State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator. Zhang, Z.R., Song, B., McCarty, N.A. J. Biol. Chem. (2005)
- A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating. Guo, Y., Waldron, G.J., Murrell-Lagnado, R. J. Biol. Chem. (2002)
- The role of the putative inactivation lid in sodium channel gating current immobilization. Sheets, M.F., Kyle, J.W., Hanck, D.A. J. Gen. Physiol. (2000)
- Structure of the 5th transmembrane segment of the Na,K-ATPase alpha subunit: a cysteine-scanning mutagenesis study. Guennoun, S., Horisberger, J.D. FEBS Lett. (2000)
- Evaluation of cancer-preventive activity and structure-activity relationships of 3-demethylubiquinone Q2, isolated from the ascidian Aplidium glabrum, and its synthetic analogs. Fedorov, S.N., Radchenko, O.S., Shubina, L.K., Balaneva, N.N., Bode, A.M., Stonik, V.A., Dong, Z. Pharm. Res. (2006)
- Channel-lining residues of the AMPA receptor M2 segment: structural environment of the Q/R site and identification of the selectivity filter. Kuner, T., Beck, C., Sakmann, B., Seeburg, P.H. J. Neurosci. (2001)
- Synthesis of homogenous site-selectively glycosylated proteins. Swanwick, R.S., Daines, A.M., Flitsch, S.L., Allemann, R.K. Org. Biomol. Chem. (2005)