Gene Review:
SERPINC1 - serpin peptidase inhibitor, clade C...
Homo sapiens
Synonyms:
AT3, AT3D, ATIII, Antithrombin-III, MGC22579, ...
- Activation of the fibrinolytic system and utilization of the coagulation inhibitors in sepsis: comparison with severe sepsis and septic shock. Mavrommatis, A.C., Theodoridis, T., Economou, M., Kotanidou, A., El Ali, M., Christopoulou-Kokkinou, V., Zakynthinos, S.G. Intensive care medicine. (2001)
- Hereditary thrombophilia among 217 consecutive patients with thromboembolic disease in Jordan. Awidi, A.S., Abu-Khalaf, M., Herzallah, U., Abu-Rajab, A., Shannak, M.M., Abu-Obeid, T., al-Taher, I., Anshasi, B. Am. J. Hematol. (1993)
- Plasma antithrombin III, alpha 2-plasmin inhibitor and plasminogen activities in cases of various liver diseases. Ito, K., Niwa, M., Kawada, T., Tanaka, Y. Tokai J. Exp. Clin. Med. (1986)
- Multiple organ dysfunction syndrome in bone marrow transplantation. Haire, W.D., Ruby, E.I., Gordon, B.G., Patil, K.D., Stephens, L.C., Kotulak, G.D., Reed, E.C., Vose, J.M., Bierman, P.J., Kessinger, A. JAMA (1995)
- Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease. Kalaria, R.N., Golde, T., Kroon, S.N., Perry, G. Am. J. Pathol. (1993)
- Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Baker, J.B., Low, D.A., Simmer, R.L., Cunningham, D.D. Cell (1980)
- Generation of C5a in the absence of C3: a new complement activation pathway. Huber-Lang, M., Sarma, J.V., Zetoune, F.S., Rittirsch, D., Neff, T.A., McGuire, S.R., Lambris, J.D., Warner, R.L., Flierl, M.A., Hoesel, L.M., Gebhard, F., Younger, J.G., Drouin, S.M., Wetsel, R.A., Ward, P.A. Nat. Med. (2006)
- Molecular characterization of antithrombin III (ATIII) variants using polymerase chain reaction. Identification of the ATIII Charleville as an Ala 384 Pro mutation. Molho-Sabatier, P., Aiach, M., Gaillard, I., Fiessinger, J.N., Fischer, A.M., Chadeuf, G., Clauser, E. J. Clin. Invest. (1989)
- Cloning and expression of the cDNA for human antithrombin III. Bock, S.C., Wion, K.L., Vehar, G.A., Lawn, R.M. Nucleic Acids Res. (1982)
- Oxymetholone therapy in patients with familial antithrombin III deficiency. Shibuya, A., Ninomiya, H., Nakazawa, M., Nagasawa, T., Yoda, Y., Abe, T. Thromb. Haemost. (1988)
- The quick machine--a mathematical model for the extrinsic activation of coagulation. Pohl, B., Beringer, C., Bomhard, M., Keller, F. Haemostasis (1994)
- The MDA-180 coagulation analyser: a laboratory evaluation. Mohammed, A., Mehrabani, P.A., Coombs, R., Molesworth, L., Favaloro, E.J. Pathology. (1997)
- Effect of glycosidase inhibitors on the biosynthesis of alpha 2-plasmin inhibitor and antithrombin III in Hep G2 cells. Mori, K., Wada, Y., Mimuro, J., Matsuda, M., Yoshikuni, Y., Kimura, K., Sakata, Y. Biochim. Biophys. Acta (1994)
- Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. Fourrier, F., Chopin, C., Goudemand, J., Hendrycx, S., Caron, C., Rime, A., Marey, A., Lestavel, P. Chest (1992)
- Intron structure of the human antithrombin III gene differs from that of other members of the serine protease inhibitor superfamily. Prochownik, E.V., Bock, S.C., Orkin, S.H. J. Biol. Chem. (1985)
- Important role of arginine 129 in heparin-binding site of antithrombin III. Identification of a novel mutation arginine 129 to glutamine. Gandrille, S., Aiach, M., Lane, D.A., Vidaud, D., Molho-Sabatier, P., Caso, R., de Moerloose, P., Fiessinger, J.N., Clauser, E. J. Biol. Chem. (1990)
- Isolation of a cDNA clone for human antithrombin III. Prochownik, E.V., Markham, A.F., Orkin, S.H. J. Biol. Chem. (1983)
- Natural anticoagulant pathways in normal and transplanted human hearts. Labarrere, C.A., Pitts, D., Halbrook, H., Faulk, W.P. J. Heart Lung Transplant. (1992)
- Successful detection by in situ cDNA hybridization of three members of the serpin family: angiotensinogen, alpha 1 protease inhibitor, and antithrombin III in human hepatocytes. Gaillard-Sanchez, I., Bruneval, P., Clauser, E., Belair, M.F., Da Silva, J.L., Bariety, J., Camilleri, J.P., Corvol, P. Mod. Pathol. (1990)
- Maternal and cord blood hemostasis at delivery. Schneider, D.M., von Tempelhoff, G.F., Herrle, B., Heilmann, L. Journal of perinatal medicine. (1997)
- Blood coagulability and fibrinolytic activity before and after physical training during the recovery phase of acute myocardial infarction. Suzuki, T., Yamauchi, K., Yamada, Y., Furumichi, T., Furui, H., Tsuzuki, J., Hayashi, H., Sotobata, I., Saito, H. Clinical cardiology. (1992)
- The role of the protein C-thrombomodulin system in physiologic anticoagulation during cardiopulmonary bypass. Tanaka, K., Wada, K., Morimoto, T., Shomura, S., Satoh, T., Yada, I., Yuasa, H., Kusagawa, M., Deguchi, K. ASAIO transactions / American Society for Artificial Internal Organs. (1989)
- Protein C, S and antithrombin III levels in patients with acute mechanical valve thrombosis. Tütün, U., Ulus, A.T., Aksöyek, A., Kaplan, S., Ayaz, S., Yilmaz, S., Birincioglu, L., Katircioglu, S.F. Panminerva medica. (2002)
- Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinity. Picard, V., Ersdal-Badju, E., Bock, S.C. Biochemistry (1995)
- Antithrombin III Utah: proline-407 to leucine mutation in a highly conserved region near the inhibitor reactive site. Bock, S.C., Marrinan, J.A., Radziejewska, E. Biochemistry (1988)
- Antithrombin III phenylalanines 122 and 121 contribute to its high affinity for heparin and its conformational activation. Jairajpuri, M.A., Lu, A., Desai, U., Olson, S.T., Bjork, I., Bock, S.C. J. Biol. Chem. (2003)
- Effect of cold storage on the haemostatic cascade systems. Omran, S., Hallouda, M., Essawi, F., el Attar, I., Aboul Enein, A., Gaafar, T., Afifi, N. Transfusion science. (1996)
- Alpha-2-macroglobulin is an important progressive inhibitor of thrombin in neonatal and infant plasma. Schmidt, B., Mitchell, L., Ofosu, F.A., Andrew, M. Thromb. Haemost. (1989)
- Effect of fibronectin on the binding of antithrombin III to immobilized heparin. Byun, Y., Jacobs, H.A., Feijen, J., Kim, S.W. J. Biomed. Mater. Res. (1996)
- Recombinant hirudin for the treatment of disseminated intravascular coagulation in patients with haematological malignancy. Saito, M., Asakura, H., Jokaji, H., Uotani, C., Kumabashiri, I., Morishita, E., Yamazaki, M., Aoshima, K., Matsuda, T. Blood Coagul. Fibrinolysis (1995)
- Protein C activation by recombinant thrombomodulin in plasma. Edano, T., Komine, N., Yoshizaki, H., Ohkuchi, M. Biol. Pharm. Bull. (1998)
- The effect of human thrombomodulin on the inactivation of thrombin by human antithrombin III. Hirahara, K., Koyama, M., Matsuishi, T., Kurata, M. Thromb. Res. (1990)
- Antithrombin III prophylaxis of venous thromboembolic disease after total hip or total knee replacement. Francis, C.W., Pellegrini, V.D., Harris, C.M., Marder, V.J. Am. J. Med. (1989)
- Anticoagulant and antiprotease profiles of a novel natural heparinomimetic mannopentaose phosphate sulfate (PI-88). Demir, M., Iqbal, O., Hoppensteadt, D.A., Piccolo, P., Ahmad, S., Schultz, C.L., Linhardt, R.J., Fareed, J. Clin. Appl. Thromb. Hemost. (2001)
- SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins. Pak, S.C., Kumar, V., Tsu, C., Luke, C.J., Askew, Y.S., Askew, D.J., Mills, D.R., Brömme, D., Silverman, G.A. J. Biol. Chem. (2004)
- Protein C, antithrombin III and plasminogen: effect of age, sex and blood group. Dolan, G., Neal, K., Cooper, P., Brown, P., Preston, F.E. Br. J. Haematol. (1994)
- Inactivation of factor XIa in human plasma assessed by measuring factor XIa-protease inhibitor complexes: major role for C1-inhibitor. Wuillemin, W.A., Minnema, M., Meijers, J.C., Roem, D., Eerenberg, A.J., Nuijens, J.H., ten Cate, H., Hack, C.E. Blood (1995)
- Assignment of the human antithrombin III structural gene to chromosome 1q23-25. Bock, S.C., Harris, J.F., Balazs, I., Trent, J.M. Cytogenet. Cell Genet. (1985)
- Increased endogenous thrombin generation in children with acute lymphoblastic leukemia: risk of thrombotic complications in L'Asparaginase-induced antithrombin III deficiency. Mitchell, L., Hoogendoorn, H., Giles, A.R., Vegh, P., Andrew, M. Blood (1994)