Gene Review:
PIM1 - Pim-1 proto-oncogene, serine/threonine kinase
Homo sapiens
Synonyms:
Serine/threonine-protein kinase pim-1
- Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas. Sivertsen, E.A., Galteland, E., Mu, D., Holte, H., Meza-Zepeda, L., Myklebost, O., Patzke, S., Smeland, E.B., Stokke, T. Leukemia (2006)
- Synergism of cytoplasmic kinases in IL6-induced ligand-independent activation of androgen receptor in prostate cancer cells. Kim, O., Jiang, T., Xie, Y., Guo, Z., Chen, H., Qiu, Y. Oncogene (2004)
- Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma. Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R. J. Mol. Biol. (2005)
- Pim-1 expression in prostatic intraepithelial neoplasia and human prostate cancer. Valdman, A., Fang, X., Pang, S.T., Ekman, P., Egevad, L. Prostate (2004)
- Regulated protein degradation in mitochondria. Langer, T., Neupert, W. Experientia (1996)
- Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase. Matsumoto, T., Beach, D. Cell (1991)
- Pim-1 kinase and p100 cooperate to enhance c-Myb activity. Leverson, J.D., Koskinen, P.J., Orrico, F.C., Rainio, E.M., Jalkanen, K.J., Dash, A.B., Eisenman, R.N., Ness, S.A. Mol. Cell (1998)
- The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG. Saris, C.J., Domen, J., Berns, A. EMBO J. (1991)
- Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma. Gaidano, G., Pasqualucci, L., Capello, D., Berra, E., Deambrogi, C., Rossi, D., Maria Larocca, L., Gloghini, A., Carbone, A., Dalla-Favera, R. Blood (2003)
- The YAL017 gene on the left arm of chromosome I of Saccharomyces cerevisiae encodes a putative serine/threonine protein kinase. Clark, M.W., Zhong, W.W., Keng, T., Storms, R.K., Ouellette, B.F., Barton, A., Kaback, D.B., Bussey, H. Yeast (1993)
- The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells. Zemskova, M., Sahakian, E., Bashkirova, S., Lilly, M. J. Biol. Chem. (2008)
- Investigatory and analytical approaches to differential gene expression profiling in mantle cell lymphoma. Zhu, Y., Hollmén, J., Räty, R., Aalto, Y., Nagy, B., Elonen, E., Kere, J., Mannila, H., Franssila, K., Knuutila, S. Br. J. Haematol. (2002)
- Cloning and characterization of the human PIM-1 gene: a putative oncogene related to the protein kinases. Meeker, T.C., Nagarajan, L., ar-Rushdi, A., Croce, C.M. J. Cell. Biochem. (1987)
- Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. Holder, S., Zemskova, M., Zhang, C., Tabrizizad, M., Bremer, R., Neidigh, J.W., Lilly, M.B. Mol. Cancer Ther. (2007)
- ATP-dependent proteases controlling mitochondrial function in the yeast Saccharomyces cerevisiae. Van Dyck, L., Langer, T. Cell. Mol. Life Sci. (1999)
- Transcriptional attenuation of PIM-1 gene. Nagarajan, L., Narayana, L. Biochem. Biophys. Res. Commun. (1993)
- Interactions between RPS19, mutated in Diamond-Blackfan anemia, and the PIM-1 oncoprotein. Chiocchetti, A., Gibello, L., Carando, A., Aspesi, A., Secco, P., Garelli, E., Loreni, F., Angelini, M., Biava, A., Dahl, N., Dianzani, U., Ramenghi, U., Santoro, C., Dianzani, I. Haematologica (2005)
- PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor. Maita, H., Kitaura, H., Keen, T.J., Inglehearn, C.F., Ariga, H., Iguchi-Ariga, S.M. Exp. Cell Res. (2004)
- Translocation (1;6)(p12;p23) in ANLL. Jacob, A.K., Sreekantaiah, C., Baer, M.R., Sandberg, A.A. Cancer Genet. Cytogenet. (1990)
- Gene expression profile predicts patient survival of gastric cancer after surgical resection. Chen, C.N., Lin, J.J., Chen, J.J., Lee, P.H., Yang, C.Y., Kuo, M.L., Chang, K.J., Hsieh, F.J. J. Clin. Oncol. (2005)
- Molecular dynamics study of polarizable ion models for molten AgBr. Bitrian, V., Trullàs, J. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2006)
- Ubiquitous expression and cell cycle regulation of the protein kinase PIM-1. Liang, H., Hittelman, W., Nagarajan, L. Arch. Biochem. Biophys. (1996)
- Overexpression of PIM-1 is a potential biomarker in prostate carcinoma. Xu, Y., Zhang, T., Tang, H., Zhang, S., Liu, M., Ren, D., Niu, Y. Journal of surgical oncology. (2005)