Gene Review:
MAPK13 - mitogen-activated protein kinase 13
Homo sapiens
Synonyms:
MAP kinase 13, MAP kinase p38 delta, MAPK 13, MAPK-13, Mitogen-activated protein kinase 13, ...
- p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity. Pramanik, R., Qi, X., Borowicz, S., Choubey, D., Schultz, R.M., Han, J., Chen, G. J. Biol. Chem. (2003)
- Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils. Nick, J.A., Avdi, N.J., Young, S.K., Lehman, L.A., McDonald, P.P., Frasch, S.C., Billstrom, M.A., Henson, P.M., Johnson, G.L., Worthen, G.S. J. Clin. Invest. (1999)
- A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta. Knebel, A., Morrice, N., Cohen, P. EMBO J. (2001)
- Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. Goedert, M., Cuenda, A., Craxton, M., Jakes, R., Cohen, P. EMBO J. (1997)
- Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways. Knebel, A., Haydon, C.E., Morrice, N., Cohen, P. Biochem. J. (2002)
- Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex. Efimova, T., Broome, A.M., Eckert, R.L. Mol. Cell. Biol. (2004)
- Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase. Wang, X.S., Diener, K., Manthey, C.L., Wang, S., Rosenzweig, B., Bray, J., Delaney, J., Cole, C.N., Chan-Hui, P.Y., Mantlo, N., Lichenstein, H.S., Zukowski, M., Yao, Z. J. Biol. Chem. (1997)
- Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Kumar, S., McDonnell, P.C., Gum, R.J., Hand, A.T., Lee, J.C., Young, P.R. Biochem. Biophys. Res. Commun. (1997)
- Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase. Schoorlemmer, J., Goldfarb, M. J. Biol. Chem. (2002)
- Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta. Jiang, Y., Gram, H., Zhao, M., New, L., Gu, J., Feng, L., Di Padova, F., Ulevitch, R.J., Han, J. J. Biol. Chem. (1997)
- Molecular basis for p38 protein kinase inhibitor specificity. Lisnock, J., Tebben, A., Frantz, B., O'Neill, E.A., Croft, G., O'Keefe, S.J., Li, B., Hacker, C., de Laszlo, S., Smith, A., Libby, B., Liverton, N., Hermes, J., LoGrasso, P. Biochemistry (1998)
- Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope. Yoshida, H., Goedert, M. J. Neurochem. (2006)
- Identification of stathmin as a novel substrate for p38 delta. Parker, C.G., Hunt, J., Diener, K., McGinley, M., Soriano, B., Keesler, G.A., Bray, J., Yao, Z., Wang, X.S., Kohno, T., Lichenstein, H.S. Biochem. Biophys. Res. Commun. (1998)
- A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation. Efimova, T., Broome, A.M., Eckert, R.L. J. Biol. Chem. (2003)
- The L1 retroelement-related p40 protein induces p38delta MAP kinase. Kuchen, S., Seemayer, C.A., Rethage, J., von Knoch, R., Kuenzler, P., Beat, A.M., Gay, R.E., Gay, S., Neidhart, M. Autoimmunity (2004)
- Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines. Hu, M.C., Wang, Y.P., Mikhail, A., Qiu, W.R., Tan, T.H. J. Biol. Chem. (1999)
- Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly. Feijoo, C., Campbell, D.G., Jakes, R., Goedert, M., Cuenda, A. J. Cell. Sci. (2005)
- Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages. Hale, K.K., Trollinger, D., Rihanek, M., Manthey, C.L. J. Immunol. (1999)
- Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways. Börsch-Haubold, A.G., Ghomashchi, F., Pasquet, S., Goedert, M., Cohen, P., Gelb, M.H., Watson, S.P. Eur. J. Biochem. (1999)