Gene Review:
CAPN2 - calpain 2, (m/II) large subunit
Homo sapiens
Synonyms:
CANP 2, CANP2, CANPL2, CANPml, Calcium-activated neutral proteinase 2, ...
- Calcium-activated neutral proteinase of human brain: subunit structure and enzymatic properties of multiple molecular forms. Vitto, A., Nixon, R.A. J. Neurochem. (1986)
- Hydrolytic and autolytic behavior of two forms of calcium-activated neutral protease (CANP). Inomata, M., Hayashi, M., Nakamura, M., Imahori, K., Kawashima, S. J. Biochem. (1985)
- Importance of monitoring calcium & calcium related properties in carrier detection for Duchenne muscular dystrophy. Jagadeesh, G., Shailaja, B., Moses, L., Kumari, C.K., Anjaneyulu, A., Anandaraj, M.P. Indian J. Med. Res. (1994)
- Increased M-calpain expression in the mesencephalon of patients with Parkinson's disease but not in other neurodegenerative disorders involving the mesencephalon: a role in nerve cell death? Mouatt-Prigent, A., Karlsson, J.O., Agid, Y., Hirsch, E.C. Neuroscience (1996)
- Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain. Satish, L., Blair, H.C., Glading, A., Wells, A. Mol. Cell. Biol. (2005)
- Functional properties of recombinant calpain I and of mutants lacking domains III and IV of the catalytic subunit. Vilei, E.M., Calderara, S., Anagli, J., Berardi, S., Hitomi, K., Maki, M., Carafoli, E. J. Biol. Chem. (1997)
- Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease. Hata, A., Ohno, S., Akita, Y., Suzuki, K. J. Biol. Chem. (1989)
- Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2. Liu, J., Yuan, Y., Huan, J., Shen, Z. Oncogene (2001)
- Multiple signaling pathways mediate compaction of collagen matrices by EGF-stimulated fibroblasts. Smith, K.D., Wells, A., Lauffenburger, D.A. Exp. Cell Res. (2006)
- Transactivation of capn2 by myogenic regulatory factors during myogenesis. Dedieu, S., Mazères, G., Dourdin, N., Cottin, P., Brustis, J.J. J. Mol. Biol. (2003)
- Immunoassay and activity of calcium-activated neutral proteinase (mCANP): distribution in soluble and membrane-associated fractions in human and mouse brain. Takeuchi, K.H., Saito, K.I., Nixon, R.A. J. Neurochem. (1992)
- Multiple proteases regulate neurite outgrowth in NB2a/dl neuroblastoma cells. Shea, T.B., Beermann, M.L., Nixon, R.A. J. Neurochem. (1991)
- Ganglioside-modulated proteolysis by Ca2(+)-activated neutral proteinase (CANP): a role of glycoconjugates in CANP regulation. Chakrabarti, A.K., Dasgupta, S., Banik, N.L., Hogan, E.L. J. Neurochem. (1990)
- Calcium-activated neutral proteinase (CANP; calpain) activity in Schwann cells: immunofluorescence localization and compartmentation of mu- and mCANP. Banik, N.L., DeVries, G.H., Neuberger, T., Russell, T., Chakrabarti, A.K., Hogan, E.L. J. Neurosci. Res. (1991)
- Generation of spectrin breakdown products in peripheral nerves by addition of M-calpain. Castejon, M.S., Culver, D.G., Glass, J.D. Muscle Nerve (1999)
- Specificity of calcium-activated neutral proteinase (CANP) inhibitors for human mu CANP and mCANP. Saito, K., Nixon, R.A. Neurochem. Res. (1993)
- Different expression patterns of calpain isozymes 1 and 2 (CAPN1 and 2) in squamous cell carcinomas (SCC) and basal cell carcinomas (BCC) of human skin. Reichrath, J., Welter, C., Mitschele, T., Classen, U., Meineke, V., Tilgen, W., Seifert, M. J. Pathol. (2003)
- Externalization of calpain (calcium-dependent neutral cysteine proteinase) in human arthritic cartilage. Szomor, Z., Shimizu, K., Yamamoto, S., Yasuda, T., Ishikawa, H., Nakamura, T. Clinical and experimental rheumatology. (1999)