Gene Review:
Sep15 - selenoprotein
Mus musculus
Synonyms:
15 kDa selenoprotein, 9430015P09Rik
- Fetal mouse selenophosphate synthetase 2 (SPS2): characterization of the cysteine mutant form overproduced in a baculovirus-insect cell system. Kim, I.Y., Guimarães, M.J., Zlotnik, A., Bazan, J.F., Stadtman, T.C. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model. Diwadkar-Navsariwala, V., Prins, G.S., Swanson, S.M., Birch, L.A., Ray, V.H., Hedayat, S., Lantvit, D.L., Diamond, A.M. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. Burk, R.F., Hill, K.E. Annu. Rev. Nutr. (2005)
- Selenium and brain function: a poorly recognized liaison. Schweizer, U., Bräuer, A.U., Köhrle, J., Nitsch, R., Savaskan, N.E. Brain Res. Brain Res. Rev. (2004)
- Possible involvement of reactive oxygen species in D-galactosamine-induced sensitization against tumor necrosis factor-alpha-induced hepatocyte apoptosis. Osawa, Y., Nagaki, M., Banno, Y., Yamada, Y., Imose, M., Nozawa, Y., Moriwaki, H., Nakashima, S. J. Cell. Physiol. (2001)
- Coupled tRNA(Sec)-dependent assembly of the selenocysteine decoding apparatus. Zavacki, A.M., Mansell, J.B., Chung, M., Klimovitsky, B., Harney, J.W., Berry, M.J. Mol. Cell (2003)
- Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. McClung, J.P., Roneker, C.A., Mu, W., Lisk, D.J., Langlais, P., Liu, F., Lei, X.G. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems. Sun, Q.A., Kirnarsky, L., Sherman, S., Gladyshev, V.N. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp). Bösl, M.R., Takaku, K., Oshima, M., Nishimura, S., Taketo, M.M. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Ghassabeh, G.H., De Baetselier, P., Brys, L., Noël, W., Van Ginderachter, J.A., Meerschaut, S., Beschin, A., Brombacher, F., Raes, G. Blood (2006)
- Cloning of murine SeGpx cDNA and synthesis of mutated GPx proteins in Escherichia coli. Rocher, C., Faucheu, C., Hervé, F., Bénicourt, C., Lalanne, J.L. Gene (1991)
- Selective inhibition of selenocysteine tRNA maturation and selenoprotein synthesis in transgenic mice expressing isopentenyladenosine-deficient selenocysteine tRNA. Moustafa, M.E., Carlson, B.A., El-Saadani, M.A., Kryukov, G.V., Sun, Q.A., Harney, J.W., Hill, K.E., Combs, G.F., Feigenbaum, L., Mansur, D.B., Burk, R.F., Berry, M.J., Diamond, A.M., Lee, B.J., Gladyshev, V.N., Hatfield, D.L. Mol. Cell. Biol. (2001)
- Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element. Korotkov, K.V., Novoselov, S.V., Hatfield, D.L., Gladyshev, V.N. Mol. Cell. Biol. (2002)
- New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements. Kryukov, G.V., Kryukov, V.M., Gladyshev, V.N. J. Biol. Chem. (1999)
- Structure-expression relationships of the 15-kDa selenoprotein gene. Possible role of the protein in cancer etiology. Kumaraswamy, E., Malykh, A., Korotkov, K.V., Kozyavkin, S., Hu, Y., Kwon, S.Y., Moustafa, M.E., Carlson, B.A., Berry, M.J., Lee, B.J., Hatfield, D.L., Diamond, A.M., Gladyshev, V.N. J. Biol. Chem. (2000)
- Multiple controls over the efficiency of translation of the mRNAs encoding transition proteins, protamines, and the mitochondrial capsule selenoprotein in late spermatids in mice. Kleene, K.C. Dev. Biol. (1993)
- Intracellular 58-kd selenoprotein levels correlate with inhibition of DNA synthesis in mammary epithelial cells. Morrison, D.G., Dishart, M.K., Medina, D. Carcinogenesis (1988)
- Differential expression of selenoproteins by human skin cells and protection by selenium from UVB-radiation-induced cell death. Rafferty, T.S., McKenzie, R.C., Hunter, J.A., Howie, A.F., Arthur, J.R., Nicol, F., Beckett, G.J. Biochem. J. (1998)
- A novel cysteine-rich domain of Sep15 mediates the interaction with UDP-glucose:glycoprotein glucosyltransferase. Labunskyy, V.M., Ferguson, A.D., Fomenko, D.E., Chelliah, Y., Hatfield, D.L., Gladyshev, V.N. J. Biol. Chem. (2005)
- Selective rescue of selenoprotein expression in mice lacking a highly specialized methyl group in selenocysteine tRNA. Carlson, B.A., Xu, X.M., Gladyshev, V.N., Hatfield, D.L. J. Biol. Chem. (2005)
- cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis. Mihara, H., Kurihara, T., Watanabe, T., Yoshimura, T., Esaki, N. J. Biol. Chem. (2000)
- Serine and methionine enhancement of selenite inhibition of DNA synthesis in a mouse mammary epithelial cell line. Morrison, D.G., Dishart, M.K., Medina, D. Carcinogenesis (1988)
- Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium. Kumaraswamy, E., Carlson, B.A., Morgan, F., Miyoshi, K., Robinson, G.W., Su, D., Wang, S., Southon, E., Tessarollo, L., Lee, B.J., Gladyshev, V.N., Hennighausen, L., Hatfield, D.L. Mol. Cell. Biol. (2003)
- Characterization of alternative cytosolic forms and cellular targets of mouse mitochondrial thioredoxin reductase. Turanov, A.A., Su, D., Gladyshev, V.N. J. Biol. Chem. (2006)
- Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression. Irons, R., Carlson, B.A., Hatfield, D.L., Davis, C.D. J. Nutr. (2006)
- Knockout of cellular glutathione peroxidase affects selenium-dependent parameters similarly in mice fed adequate and excessive dietary selenium. Cheng, W.H., Combs, G.F., Lei, X.G. Biofactors (1998)
- Genes involved in nonpermissive temperature-induced cell differentiation in Sertoli TTE3 cells bearing temperature-sensitive simian virus 40 large T-antigen. Tabuchi, Y., Kondo, T., Suzuki, Y., Obinata, M. Biochem. Biophys. Res. Commun. (2005)
- Brainstem axonal degeneration in mice with deletion of selenoprotein p. Valentine, W.M., Hill, K.E., Austin, L.M., Valentine, H.L., Goldowitz, D., Burk, R.F. Toxicologic pathology. (2005)
- Expression pattern of the mitochondrial capsule selenoprotein mRNA in the mouse testis after puberty; in situ hybridization study. Nam, S.Y., Maeda, S., Ogawa, K., Kurohmaru, M., Hayashi, Y. J. Vet. Med. Sci. (1997)