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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Self Medication

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Disease relevance of Self Medication

  • The results should not be construed as pointing to a potential way of preventing lung cancer in individuals who continue to smoke or as supporting self-medication with large doses of folate or B12 by smokers [1].
  • The patient treated with DBS developed severe dyskinesia a few days after discharge and began self medication with amantadine but showed no improvement [2].
  • We describe a patient with rheumatoid arthritis and widespread joint and periarticular calcinosis related to self-medication with vitamin D, which was aggravated by oral phosphate therapy prescribed for her hypercalcaemia [3].
  • Patient self-medication with over-the-counter products, including H2-receptor antagonists, may have an impact on the potential for reducing the recurrence of peptic ulcer disease in patients with H pylori infection [4].
  • Evaluation of the 132 cases of chronic hypervitaminosis-A showed that approximately one quarter cannot be considered as genuine cases, whereas the rest is divided almost equally between vitamin A prescription and self-medication [5].

Psychiatry related information on Self Medication


High impact information on Self Medication

  • Self-medication with zidovudine that was not [9].
  • FINDINGS: After losses from follow-up (11) or because of self-medication with quinine (four), 41 patients treated with chloroquine and 40 treated with pyronaridine were analysed [10].
  • 6.6% of all Australian patients attending an antenatal clinic were found to be taking salicylate preparations regularly, most commonly in powder form and almost always as self-medication [11].
  • INTERVENTION: Self-medication with hydrazine sulfate [12].
  • Separate causal mechanisms in each direction might also operate, including self-medication of depressed mood as a factor in smoking progression and neuropharmacologic effects of nicotine and other smoke substances on neurotransmitter systems linked to depression [13].

Chemical compound and disease context of Self Medication


Biological context of Self Medication


Anatomical context of Self Medication


Associations of Self Medication with chemical compounds


Gene context of Self Medication

  • This pattern of cocaine use is consistent with clinical descriptions of self-medication of residual symptoms of ADHD in cocaine abusers [25].
  • These data indicate intranasal glucagon as a possible emergency remedy for self-medication in insulin-treated patients prone to hypoglycemic episodes [26].
  • Comments on the report of the BSAC working party (WP) on self-medication of antibacterials without prescription [27].
  • 4. Knowledge about dosages, the possibility of adverse reactions, and the seriousness of potential poisoning with OTC drugs was inadequate and needs to be corrected for more efficient self-medication [28].
  • CONCLUSIONS: Successful MDI/DED teaching followed by self-medication is feasible in the emergency setting, based on a simple protocol [29].

Analytical, diagnostic and therapeutic context of Self Medication


  1. Improvement in bronchial squamous metaplasia in smokers treated with folate and vitamin B12. Report of a preliminary randomized, double-blind intervention trial. Heimburger, D.C., Alexander, C.B., Birch, R., Butterworth, C.E., Bailey, W.C., Krumdieck, C.L. JAMA (1988) [Pubmed]
  2. Dyskinesias induced by subthalamotomy in Parkinson's disease are unresponsive to amantadine. Merello, M., Perez-Lloret, S., Antico, J., Obeso, J.A. J. Neurol. Neurosurg. Psychiatr. (2006) [Pubmed]
  3. Calcinosis of joints and periarticular tissues associated with vitamin D intoxication. Butler, R.C., Dieppe, P.A., Keat, A.C. Ann. Rheum. Dis. (1985) [Pubmed]
  4. Pathogenesis and treatment of acid peptic disorders: comparison of proton pump inhibitors with other antiulcer agents. Sanders, S.W. Clinical therapeutics. (1996) [Pubmed]
  5. New aspects of the tolerance of retinol in humans. Körner, W.F., Völlm, J. International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition. (1975) [Pubmed]
  6. Nicotine treatment of obsessive-compulsive disorder. Lundberg, S., Carlsson, A., Norfeldt, P., Carlsson, M.L. Prog. Neuropsychopharmacol. Biol. Psychiatry (2004) [Pubmed]
  7. Chocolate: food or drug? Bruinsma, K., Taren, D.L. Journal of the American Dietetic Association. (1999) [Pubmed]
  8. Investigation of mechanisms linking depressed mood to nicotine dependence. Lerman, C., Audrain, J., Orleans, C.T., Boyd, R., Gold, K., Main, D., Caporaso, N. Addictive behaviors. (1996) [Pubmed]
  9. Self-medication with zidovudine that was not. Apoola, A., Sriskandabalan, P.S., Wade, A.A. Lancet (2001) [Pubmed]
  10. Randomised trial of pyronaridine versus chloroquine for acute uncomplicated falciparum malaria in Africa. Ringwald, P., Bickii, J., Basco, L. Lancet (1996) [Pubmed]
  11. Maternal effects of regular salicylate ingestion in pregnancy. Collins, E., Turner, G. Lancet (1975) [Pubmed]
  12. Fatal hepatorenal failure associated with hydrazine sulfate. Hainer, M.I., Tsai, N., Komura, S.T., Chiu, C.L. Ann. Intern. Med. (2000) [Pubmed]
  13. Major depression and stages of smoking. A longitudinal investigation. Breslau, N., Peterson, E.L., Schultz, L.R., Chilcoat, H.D., Andreski, P. Arch. Gen. Psychiatry (1998) [Pubmed]
  14. Self-medication with pilocarpine among outpatients in a glaucoma clinic. Norell, S.E., Granström, P.A. The British journal of ophthalmology. (1980) [Pubmed]
  15. Methemoglobinemia and acute hemolysis after tetracaine lozenge use. Lavergne, S., Darmon, M., Levy, V., Azoulay, E. Journal of critical care. (2006) [Pubmed]
  16. Liquorice, growth retardation and Addison's disease. Doeker, B.M., Andler, W. Horm. Res. (1999) [Pubmed]
  17. Psychotherapy of nine successfully treated cocaine abusers: techniques and dynamics. Schiffer, F. Journal of substance abuse treatment. (1988) [Pubmed]
  18. Nicotine psychobiology: how chronic-dose prospective studies can illuminate some of the theoretical issues from acute-dose research. Parrott, A.C. Psychopharmacology (Berl.) (2006) [Pubmed]
  19. A newly devised formulation for self-medication enhances interferon-gamma production and proliferation of splenic lymphocytes. Tega, E., Kiga, C., Chino, A., Sakurai, H., Koizumi, K., Tani, T., Saiki, I. Biol. Pharm. Bull. (2005) [Pubmed]
  20. The effect of compliance with treatment on survival among patients with hematologic malignancies. Richardson, J.L., Shelton, D.R., Krailo, M., Levine, A.M. J. Clin. Oncol. (1990) [Pubmed]
  21. The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. Khantzian, E.J. The American journal of psychiatry. (1985) [Pubmed]
  22. Self-medication with pseudoephedrine in a chronically depressed patient. Diaz, M.A., Wise, T.N., Semchyshyn, G.O. The American journal of psychiatry. (1979) [Pubmed]
  23. Electrophysiological evidence of serotonergic impairment in long-term MDMA ("ecstasy") users. Croft, R.J., Klugman, A., Baldeweg, T., Gruzelier, J.H. The American journal of psychiatry. (2001) [Pubmed]
  24. Effects of 24 hours of aspirin, Bufferin, paracetamol and placebo on normal human gastroduodenal mucosa. Hoftiezer, J.W., O'Laughlin, J.C., Ivey, K.J. Gut (1982) [Pubmed]
  25. History and significance of childhood attention deficit disorder in treatment-seeking cocaine abusers. Carroll, K.M., Rounsaville, B.J. Comprehensive psychiatry. (1993) [Pubmed]
  26. Intranasal glucagon as remedy for hypoglycemia. Studies in healthy subjects and type I diabetic patients. Pontiroli, A.E., Calderara, A., Pajetta, E., Alberetto, M., Pozza, G. Diabetes Care (1989) [Pubmed]
  27. Comments on the report of the BSAC working party (WP) on self-medication of antibacterials without prescription. Alfandari, S., Beaucaire, G. J. Antimicrob. Chemother. (2000) [Pubmed]
  28. Self-medication in urban and rural Zimbabwean communities. Stein, C.M., Gora, N.P., Macheka, B.M. British journal of clinical pharmacology. (1989) [Pubmed]
  29. Teaching time for metered-dose inhalers in the emergency setting. Numata, Y., Bourbeau, J., Ernst, P., Duquette, G., Schwartzman, K. Chest (2002) [Pubmed]
  30. Acute dystonia in labour: side-effect of concealed self-medication attributed to epidural analgesia. Jankowski, S., Arrigoni, P.B. International journal of obstetric anesthesia. (1993) [Pubmed]
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