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MeSH Review

Platyrrhini

 
 
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Disease relevance of Platyrrhini

 

High impact information on Platyrrhini

 

Biological context of Platyrrhini

 

Anatomical context of Platyrrhini

 

Associations of Platyrrhini with chemical compounds

 

Gene context of Platyrrhini

  • These observations suggest that a triplication of the haptoglobin locus occurred after the divergence of the new world monkeys, followed by a deletion of one locus in humans [21].
  • This additional intron is also found in the Surf-5 gene of both Old and New World monkeys, being generated before the divergence of human and prosimians but after the divergence of primates and rodents [22].
  • MHC-G intron 2 from New World monkeys does not show the typical 23 bp deletion found in all other more recent primate species [23].
  • Interesting trends include an unusually low number of synonymous substitutions (Ks) observed among the New World monkey RNase k6 genes [8].
  • Interestingly, acquisition of antiviral activity parallels the evolutionary development of the primate EDN lineage, having emerged some time after the divergence of the Old World from the New World monkeys [24].
 

Analytical, diagnostic and therapeutic context of Platyrrhini

References

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  8. Ribonuclease k6: chromosomal mapping and divergent rates of evolution within the RNase A gene superfamily. Deming, M.S., Dyer, K.D., Bankier, A.T., Piper, M.B., Dear, P.H., Rosenberg, H.F. Genome Res. (1998) [Pubmed]
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  21. Complex events in the evolution of the haptoglobin gene cluster in primates. McEvoy, S.M., Maeda, N. J. Biol. Chem. (1988) [Pubmed]
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  23. Evolution of MHC-G in primates: a different kind of molecule for each group of species. Arnaiz-Villena, A., Morales, P., Gomez-Casado, E., Castro, M.J., Varela, P., Rojo-Amigo, R., Martinez-Laso, J. J. Reprod. Immunol. (1999) [Pubmed]
  24. Evolution of antiviral activity in the ribonuclease A gene superfamily: evidence for a specific interaction between eosinophil-derived neurotoxin (EDN/RNase 2) and respiratory syncytial virus. Domachowske, J.B., Bonville, C.A., Dyer, K.D., Rosenberg, H.F. Nucleic Acids Res. (1998) [Pubmed]
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