Chemical Compound Review:
Micardis 2-[4-[[4-methyl-6-(1- methylbenzoimidazol-2...
Synonyms:
Kinzal, Kinzalmono, Pritor, Targit, Telmisartan, ...
Janke,
Schupp,
Engeli,
Gorzelniak,
Boschmann,
Sauma,
Nystrom,
Jordan,
Luft,
Sharma,
Kurtz,
Pravenec,
Mori,
Itoh,
Tajima,
Manolis,
Reid,
de Zeeuw,
Murphy,
Seewaldt-Becker,
Köster,
Maillard,
Perregaux,
Centeno,
Stangier,
Wienen,
Brunner,
Burnier,
Nap,
Balt,
Pfaffendorf,
Van Zwieten,
Link,
Lenz,
Legner,
Böhm,
Nickenig,
Balt,
Mathy,
Pfaffendorf,
van Zwieten,
Lijnen,
Petrov,
Fagard,
- Molecular Characterization of New Selective Peroxisome Proliferator-Activated Receptor {gamma} Modulators With Angiotensin Receptor Blocking Activity. Schupp, M., Clemenz, M., Gineste, R., Witt, H., Janke, J., Helleboid, S., Hennuyer, N., Ruiz, P., Unger, T., Staels, B., Kintscher, U. Diabetes (2005)
- Insulin-sensitizing effects of telmisartan: implications for treating insulin-resistant hypertension and cardiovascular disease. Pershadsingh, H.A., Kurtz, T.W. Diabetes Care (2004)
- Telmisartan: a review of its use in the management of hypertension. Battershill, A.J., Scott, L.J. Drugs (2006)
- Telmisartan. McClellan, K.J., Markham, A. Drugs (1998)
- Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions. Böhm, M., Lee, M., Kreutz, R., Kim, S., Schinke, M., Djavidani, B., Wagner, J., Kaling, M., Wienen, W., Bader, M. J. Hypertens. (1995)
- Angiotensin II Receptor Blockers Downsize Adipocytes in Spontaneously Type 2 Diabetic Rats With Visceral Fat Obesity. Mori, Y., Itoh, Y., Tajima, N. Am. J. Hypertens. (2007)
- Inhibition of angiotensin I-converting enzyme induces radioprotection by preserving murine hematopoietic short-term reconstituting cells. Charrier, S., Michaud, A., Badaoui, S., Giroux, S., Ezan, E., Sainteny, F., Corvol, P., Vainchenker, W. Blood (2004)
- Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation. Yoshida, T., Yamagishi, S., Nakamura, K., Matsui, T., Imaizumi, T., Takeuchi, M., Koga, H., Ueno, T., Sata, M. Diabetologia (2006)
- Telmisartan inhibits beta2-integrin MAC-1 expression in human T-lymphocytes. Link, A., Lenz, M., Legner, D., Böhm, M., Nickenig, G. J. Hypertens. (2006)
- Antidiabetic mechanisms of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists: beyond the renin-angiotensin system. Kurtz, T.W., Pravenec, M. J. Hypertens. (2004)
- Telmisartan/hydrochlorothiazide: in the treatment of essential hypertension. Fenton, C., Keating, G.M., Scott, L.J. Drugs (2003)
- Efficacy and safety of telmisartan, a selective AT1 receptor antagonist, compared with enalapril in elderly patients with primary hypertension. TEES Study Group. Karlberg, B.E., Lins, L.E., Hermansson, K. J. Hypertens. (1999)
- Effects of telmisartan 80 mg and valsartan 160 mg on ambulatory blood pressure in patients with essential hypertension. Calvo, C., Hermida, R.C., Ayala, D.E., Ruilope, L.M. J. Hypertens. (2004)
- Neuroprotective Effects of Angiotensin II Type 1 Receptor (AT1R) Blocker, Telmisartan, via Modulating AT1R and AT2R Signaling in Retinal Inflammation. Kurihara, T., Ozawa, Y., Shinoda, K., Nagai, N., Inoue, M., Oike, Y., Tsubota, K., Ishida, S., Okano, H. Invest. Ophthalmol. Vis. Sci. (2006)
- Telmisartan downregulates angiotensin II type 1 receptor through activation of peroxisome proliferator-activated receptor gamma. Imayama, I., Ichiki, T., Inanaga, K., Ohtsubo, H., Fukuyama, K., Ono, H., Hashiguchi, Y., Sunagawa, K. Cardiovasc. Res. (2006)
- Angiotensin type 1 receptor antagonists induce human in-vitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation. Janke, J., Schupp, M., Engeli, S., Gorzelniak, K., Boschmann, M., Sauma, L., Nystrom, F.H., Jordan, J., Luft, F.C., Sharma, A.M. J. Hypertens. (2006)
- Suppression of ocular inflammation in endotoxin-induced uveitis by blocking the angiotensin II type 1 receptor. Nagai, N., Oike, Y., Noda, K., Urano, T., Kubota, Y., Ozawa, Y., Shinoda, H., Koto, T., Shinoda, K., Inoue, M., Tsubota, K., Yamashiro, K., Suda, T., Ishida, S. Invest. Ophthalmol. Vis. Sci. (2005)
- Angiotensin II receptor antagonist telmisartan in isolated systolic hypertension (ARAMIS) study: efficacy and safety of telmisartan 20, 40 or 80 mg versus hydrochlorothiazide 12.5 mg or placebo. Manolis, A.J., Reid, J.L., de Zeeuw, D., Murphy, M.B., Seewaldt-Becker, E., Köster, J. J. Hypertens. (2004)
- Sympatholytic properties of several AT1-receptor antagonists in the isolated rabbit thoracic aorta. Nap, A., Balt, J.C., Pfaffendorf, M., Van Zwieten, P.A. J. Hypertens. (2002)
- In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist. Maillard, M.P., Perregaux, C., Centeno, C., Stangier, J., Wienen, W., Brunner, H.R., Burnier, M. J. Pharmacol. Exp. Ther. (2002)
- Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans. Ishiguro, N., Maeda, K., Kishimoto, W., Saito, A., Harada, A., Ebner, T., Roth, W., Igarashi, T., Sugiyama, Y. Drug Metab. Dispos. (2006)
- Angiotensin II Type 1 Receptor-Mediated Inflammation Is Required for Choroidal Neovascularization. Nagai, N., Oike, Y., Izumi-Nagai, K., Urano, T., Kubota, Y., Noda, K., Ozawa, Y., Inoue, M., Tsubota, K., Suda, T., Ishida, S. Arterioscler. Thromb. Vasc. Biol. (2006)
- Induction of cardiac fibrosis by angiotensin II. Lijnen, P.J., Petrov, V.V., Fagard, R.H. Methods and findings in experimental and clinical pharmacology. (2000)
- The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I). Williams, B., Gosse, P., Lowe, L., Harper, R. J. Hypertens. (2006)
- Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor. Nagai, N., Noda, K., Urano, T., Kubota, Y., Shinoda, H., Koto, T., Shinoda, K., Inoue, M., Shiomi, T., Ikeda, E., Tsubota, K., Suda, T., Oike, Y., Ishida, S. Invest. Ophthalmol. Vis. Sci. (2005)
- Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril. Balt, J.C., Mathy, M.J., Pfaffendorf, M., van Zwieten, P.A. J. Hypertens. (2001)