The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Midline Thalamic Nuclei

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Midline Thalamic Nuclei


Biological context of Midline Thalamic Nuclei


Anatomical context of Midline Thalamic Nuclei


Associations of Midline Thalamic Nuclei with chemical compounds

  • Other midline diencephalic structures were found to have high densities of dopamine-beta-hydroxylase immunoreactivity, including the paraventricular nucleus of the thalamus and a discrete subregion of nucleus reuniens, the magnocellular subfascicular nucleus [12].
  • Repeated injection of 25 nmol/0.5 microliters NMDA (experimental group) into the massa intermedia (MI), particularly into the reuniens nucleus, caused tonic and/or clonic generalized convulsion associated with temporal limbic EEG seizure discharge [13].
  • Serotonin and most of the peptides were found throughout paraventricular thalamic nucleus (PV) and in other midline and intralaminar nuclei (type 1 pattern) [14].
  • In the nucleus reuniens, the distribution of 5-HT-, TH-, substance P-, and menkephalin-immunolabelling resembles that seen in the torus semicircularis, but at a lower density [15].
  • For example, E, P and E + P all significantly increased 3H muscimol binding in medial preoptic area, ventromedial hypothalamic nuclei, and vertical diagonal bandmedial septal nucleus, whereas P treatment increased binding in the caudate-putamen and decreased it in reuniens nucleus of the thalamus [16].

Gene context of Midline Thalamic Nuclei

  • Additional CR immunostaining of the subcortical region unveiled retrogradely labeled neurons that were also immunostained for CR only in the supramammillary area and the nucleus reuniens [17].
  • CMS dramatically produced a decrease in NPY expression in several diencephalic regions including the parvocellular subregion of the paraventricular hypothalamic nucleus (PVN), the periventricular hypothalamic nucleus (PE), the paraventricular thalamic nucleus (PV) and the arcuate nucleus (ACN) [18].
  • In contrast, mGluR5 mRNA was more uniformly distributed at weak to moderate levels, except in the reuniens nucleus where a strong signal was detected [19].
  • Fibers projecting from SCN neurons that are immunoreactive for AVP and VIP exhibit a characteristic morphology, and project to the lateral septum, a series of medial hypothalamic areas extending from the preoptic to the posterior hypothalamic area and to the paraventricular thalamic nucleus [20].
  • This increase was not due to methodological factors, since no changes in NR1 labeling density were found in a nearby nucleus, the nucleus reuniens [21].

Analytical, diagnostic and therapeutic context of Midline Thalamic Nuclei


  1. A cholecystokinin-mediated pathway to the paraventricular thalamus is recruited in chronically stressed rats and regulates hypothalamic-pituitary-adrenal function. Bhatnagar, S., Viau, V., Chu, A., Soriano, L., Meijer, O.C., Dallman, M.F. J. Neurosci. (2000) [Pubmed]
  2. Neuronal nicotinic acetylcholine receptor subunits in autism: an immunohistochemical investigation in the thalamus. Ray, M.A., Graham, A.J., Lee, M., Perry, R.H., Court, J.A., Perry, E.K. Neurobiol. Dis. (2005) [Pubmed]
  3. Differential age-related changes of MAO-A and MAO-B in mouse brain and peripheral organs. Saura, J., Richards, J.G., Mahy, N. Neurobiol. Aging (1994) [Pubmed]
  4. Prefrontal cortex-projecting glutamatergic thalamic paraventricular nucleus-excited by hypocretin: a feedforward circuit that may enhance cognitive arousal. Huang, H., Ghosh, P., van den Pol, A.N. J. Neurophysiol. (2006) [Pubmed]
  5. Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development. Austin, C.P., Ky, B., Ma, L., Morris, J.A., Shughrue, P.J. Neuroscience (2004) [Pubmed]
  6. Systemic oxytocin treatment modulates alpha 2-adrenoceptors in telencephalic and diencephalic regions of the rat. Díaz-Cabiale, Z., Petersson, M., Narváez, J.A., Uvnäs-Moberg, K., Fuxe, K. Brain Res. (2000) [Pubmed]
  7. Expression of Fos-related antigens in the nucleus accumbens and associated regions following exposure to a cocaine-paired environment. Franklin, T.R., Druhan, J.P. Eur. J. Neurosci. (2000) [Pubmed]
  8. Excitotoxic lesions of the mediodorsal thalamic nucleus attenuate intravenous cocaine self-administration. Weissenborn, R., Whitelaw, R.B., Robbins, T.W., Everitt, B.J. Psychopharmacology (Berl.) (1998) [Pubmed]
  9. Organization of the thalamostriatal projections in the rat, with special emphasis on the ventral striatum. Berendse, H.W., Groenewegen, H.J. J. Comp. Neurol. (1990) [Pubmed]
  10. Msx1 disruption leads to diencephalon defects and hydrocephalus. Ramos, C., Fernández-Llebrez, P., Bach, A., Robert, B., Soriano, E. Dev. Dyn. (2004) [Pubmed]
  11. Fos expression in the rostral thalamic nuclei and associated cortical regions in response to different spatial memory tests. Vann, S.D., Brown, M.W., Aggleton, J.P. Neuroscience (2000) [Pubmed]
  12. Noradrenergic innervation of the hypothalamus of rhesus monkeys: distribution of dopamine-beta-hydroxylase immunoreactive fibers and quantitative analysis of varicosities in the paraventricular nucleus. Ginsberg, S.D., Hof, P.R., Young, W.G., Morrison, J.H. J. Comp. Neurol. (1993) [Pubmed]
  13. N-methyl-D-aspartate injection into the massa intermedia facilitates development of limbic kindling in rats. Hirayasu, Y., Wada, J.A. Epilepsia (1992) [Pubmed]
  14. Relationship of thalamic basal forebrain projection neurons to the peptidergic innervation of the midline thalamus. Freedman, L.J., Cassell, M.D. J. Comp. Neurol. (1994) [Pubmed]
  15. Evolutionary significance of different neurochemical organisation of the internal and external regions of auditory centres in the reptilian brain: an immunocytochemical and reduced NADPH-diaphorase histochemical study in turtles. Belekhova, M.G., Kenigfest-Rio, N.B., Vesselkin, N.P., Rio, J.P., Repérant, J., Ward, R. Brain Res. (2002) [Pubmed]
  16. GABA[A] receptor level changes in female hamster forebrain following in vivo estrogen progesterone and benzodiazepine treatment: a quantitative autoradiography analysis. Canonaco, M., O'Connor, L.H., Pfaff, D.W., McEwen, B.S. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1989) [Pubmed]
  17. GABAergic neurons in the rat dentate gyrus are innervated by subcortical calretinin-containing afferents. Nitsch, R., Leranth, C. J. Comp. Neurol. (1996) [Pubmed]
  18. Expression of neuropeptide Y and cholecystokinin in the rat brain by chronic mild stress. Kim, H., Whang, W.W., Kim, H.T., Pyun, K.H., Cho, S.Y., Hahm, D.H., Lee, H.J., Shim, I. Brain Res. (2003) [Pubmed]
  19. Differential distribution of metabotropic glutamate receptor subtype mRNAs in the thalamus of the rat. Lourenço Neto, F., Schadrack, J., Berthele, A., Zieglgänsberger, W., Tölle, T.R., Castro-Lopes, J.M. Brain Res. (2000) [Pubmed]
  20. Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections. Abrahamson, E.E., Moore, R.Y. Brain Res. (2001) [Pubmed]
  21. Increased expression of the N-methyl-D-aspartate receptor subunit, NR1, in immunohistochemically identified magnocellular hypothalamic neurons during dehydration. Decavel, C., Curras, M.C. Neuroscience (1997) [Pubmed]
  22. Effects of electrical stimulation of various midline thalamic nuclei on the bilateral release of dopamine from dendrites and nerve terminals of neurons in the nigro-striatal dopaminergic pathways. Chéramy, A., Romo, R., Godeheu, G., Glowinski, J. Neurosci. Lett. (1984) [Pubmed]
WikiGenes - Universities